Aortic root dimensions are predominantly determined by genetic factors: a classical twin study

• Published in: European radiology Vol. 27; no. 6; pp. 2419 - 2425
• Main Authors: Celeng, Csilla, Kolossváry, Márton, Kovács, Attila, Molnár, Andrea Ágnes, Szilveszter, Bálint, Horváth, Tamás, Károlyi, Mihály, Jermendy, Ádám L., Tárnoki, Ádám D., Tárnoki, Dávid L., Karády, Júlia, Voros, Szilard, Jermendy, György, Merkely, Béla, Maurovich-Horvat, Pál
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.06.2017; Springer Nature B.V
• Subjects: Aorta - anatomy & histology; Aorta - diagnostic imaging; Atherosclerosis; Body mass index; Cardiovascular disease; Computed Tomography; Computed Tomography Angiography - methods; Coronary vessels; Diagnostic Radiology; Doppler effect; Echocardiography - methods; Estimates; Female; Genetic Determinism; Genotype; Humans; Imaging; Imaging, Three-Dimensional - methods; Internal Medicine; Interventional Radiology; Male; Medical imaging; Medicine; Medicine & Public Health; Middle Aged; Multidetector Computed Tomography - methods; Multimodal Imaging - methods; Neuroradiology; Radiology; Sinus of Valsalva - anatomy & histology; Sinus of Valsalva - diagnostic imaging; Sinuses; Tomography; Twin studies; Twins; Twins, Dizygotic; Twins, Monozygotic; Ultrasound; Hungary; Ascending aorta; Twins; Genetic determinism; Transthoracic echocardiography; Multidetector computed tomography

Objectives Previous studies using transthoracic echocardiography (TTE) observed moderate heritability of aortic root dimensions. Computed tomography angiography (CTA) might provide more accurate heritability estimates. Our primary aim was to assess the heritability of the aortic root with CTA. Our s...