Functional Tumor Volume by Fast Dynamic Contrast‐Enhanced MRI for Predicting Neoadjuvant Systemic Therapy Response in Triple‐Negative Breast Cancer

• Published in: Journal of magnetic resonance imaging Vol. 54; no. 1; pp. 251 - 260
• Main Authors: Musall, Benjamin C., Abdelhafez, Abeer H., Adrada, Beatriz E., Candelaria, Rosalind P., Mohamed, Rania M.M., Boge, Medine, Le‐Petross, Huong, Arribas, Elsa, Lane, Deanna L., Spak, David A., Leung, Jessica W.T., Hwang, Ken‐Pin, Son, Jong Bum, Elshafeey, Nabil A., Mahmoud, Hagar S., Wei, Peng, Sun, Jia, Zhang, Shu, White, Jason B., Ravenberg, Elizabeth E., Litton, Jennifer K., Damodaran, Senthil, Thompson, Alastair M., Moulder, Stacy L., Yang, Wei T., Pagel, Mark D., Rauch, Gaiane M., Ma, Jingfei
• Format: Journal Article
• Language: English
• Published: Hoboken, USA John Wiley & Sons, Inc 01.07.2021; Wiley Subscription Services, Inc
• Subjects: Auditory discrimination; Biopsy; Breast cancer; breast MRI; Breast Neoplasms - diagnostic imaging; Breast Neoplasms - drug therapy; Confidence intervals; Contrast Media; DCE MRI; Female; Field strength; functional tumor volume; Humans; Injection; Magnetic Resonance Imaging; Neoadjuvant Therapy; Patients; Perfusion; Population studies; Prospective Studies; Statistical analysis; Statistical tests; Surgery; treatment response; Triple Negative Breast Neoplasms - diagnostic imaging; Triple Negative Breast Neoplasms - drug therapy; Triple‐negative breast cancer; Tumor Burden; Tumors; breast MRI; DCE MRI; functional tumor volume; treatment response; Triple-negative breast cancer

Background Dynamic contrast‐enhanced (DCE) MRI is useful for diagnosis and assessment of treatment response in breast cancer. Fast DCE MRI offers a higher sampling rate of contrast enhancement curves in comparison to conventional DCE MRI, potentially characterizing tumor perfusion kinetics more accu...