Click to Self‐immolation: A “Click” Functionalization Strategy towards Triggerable Self‐Immolative Homopolymers and Block Copolymers

• Published in: Angewandte Chemie International Edition Vol. 63; no. 3; pp. e202317063 - n/a
• Main Authors: Deng, Zhengyu, Liang, Xiaoli, Gillies, Elizabeth R.
• Format: Journal Article
• Language: English
• Published: Germany Wiley Subscription Services, Inc 15.01.2024
• Edition: International ed. in English
• Subjects: Block Copolymer; Block copolymers; Click Chemistry; Controlled release; Depolymerization; Functionalization; Isocyanates; Macromolecules; Nanoparticles; Polymers; Precursors; Self-Immolative Polymer; Stimuli-Responsive; Stimuli-Responsive; Block Copolymer; Functionalization; Self-Immolative Polymer; Click Chemistry

Self‐immolative polymers (SIPs) are a class of degradable macromolecules that undergo stimuli‐triggered head‐to‐tail depolymerization. However, a general approach to readily end‐functionalize SIP precursors for programmed degradation remains elusive, restricting access to complex, functional SIP‐bas...