The Rule of Thirds: Controlling Junction Chirality and Polarity in 3D DNA Tiles

• Published in: Small (Weinheim an der Bergstrasse, Germany) Vol. 19; no. 12; pp. e2206511 - n/a
• Main Authors: Vecchioni, Simon, Lu, Brandon, Janowski, Jordan, Woloszyn, Karol, Jonoska, Nataša, Seeman, Nadrian C., Mao, Chengde, Ohayon, Yoel P., Sha, Ruojie
• Format: Journal Article
• Language: English
• Published: Germany Wiley Subscription Services, Inc 01.03.2023
• Subjects: 3D DNA crystals; Base Pairing; Biological activity; chiral self‐assembly; Chirality; DNA - chemistry; DNA junctions; DNA nanotechnology; Grooves; Helices; Morphology; Nanomaterials; Nanostructures - chemistry; Nanotechnology; Nucleic Acid Conformation; Segments; Self-assembly; Tensegrity; Topology; DNA junctions; DNA nanotechnology; nanomaterials; chiral self-assembly; 3D DNA crystals

The successful self‐assembly of tensegrity triangle DNA crystals heralded the ability to programmably construct macroscopic crystalline nanomaterials from rationally‐designed, nanoscale components. This 3D DNA tile owes its “tensegrity” nature to its three rotationally stacked double helices locked...