Dysregulated Metabolic Pathways in Subjects with Obesity and Metabolic Syndrome

• Published in: International journal of molecular sciences Vol. 23; no. 17; p. 9821
• Main Authors: Mir, Fayaz Ahmad, Ullah, Ehsan, Mall, Raghvendra, Iskandarani, Ahmad, Samra, Tareq A., Cyprian, Farhan, Parray, Aijaz, Alkasem, Meis, Abdalhakam, Ibrahem, Farooq, Faisal, Abou-Samra, Abdul-Badi
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 29.08.2022; MDPI
• Subjects: Cardiovascular disease; Humans; Insulin Resistance; Lipids; Metabolic Networks and Pathways; Metabolic Syndrome; Metabolites; Obesity; Obesity - complications; Triglycerides; metabolic syndrome; sphingomyelins; inflammation; metabolomics; obesity

Background: Obesity coexists with variable features of metabolic syndrome, which is associated with dysregulated metabolic pathways. We assessed potential associations between serum metabolites and features of metabolic syndrome in Arabic subjects with obesity. Methods: We analyzed a dataset of 39 s...