Valproate decreases vitamin D levels in pediatric patients with epilepsy

• Published in: Seizure (London, England) Vol. 71; pp. 60 - 65
• Main Authors: Xu, Zejun, Jing, Xia, Li, Guizhou, Sun, Jieyu, Guo, Hongli, Hu, Yahui, Sun, Fang, Wen, Xiaoyi, Chen, Feng, Wang, Tengfei, Lu, Xiao-Peng
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.10.2019
• Subjects: 25-OH-Vit D; Adolescent; Anticonvulsants - adverse effects; Carbamazepine; Carbamazepine - adverse effects; Child; Child, Preschool; Epilepsy; Epilepsy - drug therapy; Humans; Meta-analysis; Monotherapy; Pediatric; Valproate; Valproic Acid - adverse effects; Vitamin D - blood; Vitamin D Deficiency - chemically induced; 25-OH-Vit D; Epilepsy; Monotherapy; Pediatric; Carbamazepine; Meta-analysis; Valproate

•Effects of antiepileptic drugs on Vit D levels in pediatric patients were pooled.•Vit D levels decreased in children on long-term valproate monotherapy.•Vit D decrease was also observed after carbamazepine monotherapy. To compare Vitamin D (Vit D) levels in children with epilepsy on valproate monot...