Applications of Bacillus subtilis Spores in Biotechnology and Advanced Materials
The bacterium Bacillus subtilis has long been an important subject for basic studies. However, this organism has also had industrial applications due to its easy genetic manipulation, favorable culturing characteristics for large‐scale fermentation, superior capacity for protein secretion, and gener...
Saved in:
| Published in | Applied and environmental microbiology Vol. 86; no. 17 |
|---|---|
| Main Authors | , , , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
American Society for Microbiology
18.08.2020
|
| Subjects | |
| Online Access | Get full text |
| ISSN | 0099-2240 1098-5336 1098-5336 |
| DOI | 10.1128/AEM.01096-20 |
Cover
Loading…
| Abstract | The bacterium
Bacillus subtilis
has long been an important subject for basic studies. However, this organism has also had industrial applications due to its easy genetic manipulation, favorable culturing characteristics for large‐scale fermentation, superior capacity for protein secretion, and generally recognized as safe (GRAS) status. In addition, as the metabolically dormant form of
B. subtilis
, its spores have attracted great interest due to their extreme resistance to many environmental stresses, which makes spores a novel platform for a variety of applications.
The bacterium
Bacillus subtilis
has long been an important subject for basic studies. However, this organism has also had industrial applications due to its easy genetic manipulation, favorable culturing characteristics for large‐scale fermentation, superior capacity for protein secretion, and generally recognized as safe (GRAS) status. In addition, as the metabolically dormant form of
B. subtilis
, its spores have attracted great interest due to their extreme resistance to many environmental stresses, which makes spores a novel platform for a variety of applications. In this review, we summarize both conventional and emerging applications of
B. subtilis
spores, with a focus on how their unique characteristics have led to innovative applications in many areas of technology, including generation of stable and recyclable enzymes, synthetic biology, drug delivery, and material sciences. Ultimately, this review hopes to inspire the scientific community to leverage interdisciplinary approaches using spores to address global concerns about food shortages, environmental protection, and health care. |
|---|---|
| AbstractList | The bacterium
Bacillus subtilis
has long been an important subject for basic studies. However, this organism has also had industrial applications due to its easy genetic manipulation, favorable culturing characteristics for large‐scale fermentation, superior capacity for protein secretion, and generally recognized as safe (GRAS) status. In addition, as the metabolically dormant form of
B. subtilis
, its spores have attracted great interest due to their extreme resistance to many environmental stresses, which makes spores a novel platform for a variety of applications.
The bacterium
Bacillus subtilis
has long been an important subject for basic studies. However, this organism has also had industrial applications due to its easy genetic manipulation, favorable culturing characteristics for large‐scale fermentation, superior capacity for protein secretion, and generally recognized as safe (GRAS) status. In addition, as the metabolically dormant form of
B. subtilis
, its spores have attracted great interest due to their extreme resistance to many environmental stresses, which makes spores a novel platform for a variety of applications. In this review, we summarize both conventional and emerging applications of
B. subtilis
spores, with a focus on how their unique characteristics have led to innovative applications in many areas of technology, including generation of stable and recyclable enzymes, synthetic biology, drug delivery, and material sciences. Ultimately, this review hopes to inspire the scientific community to leverage interdisciplinary approaches using spores to address global concerns about food shortages, environmental protection, and health care. The bacterium Bacillus subtilis has long been an important subject for basic studies. However, this organism has also had industrial applications due to its easy genetic manipulation, favorable culturing characteristics for large-scale fermentation, superior capacity for protein secretion, and generally recognized as safe (GRAS) status. In addition, as the metabolically dormant form of B. subtilis, its spores have attracted great interest due to their extreme resistance to many environmental stresses, which makes spores a novel platform for a variety of applications. In this review, we summarize both conventional and emerging applications of B. subtilis spores, with a focus on how their unique characteristics have led to innovative applications in many areas of technology, including generation of stable and recyclable enzymes, synthetic biology, drug delivery, and material sciences. Ultimately, this review hopes to inspire the scientific community to leverage interdisciplinary approaches using spores to address global concerns about food shortages, environmental protection, and health care.The bacterium Bacillus subtilis has long been an important subject for basic studies. However, this organism has also had industrial applications due to its easy genetic manipulation, favorable culturing characteristics for large-scale fermentation, superior capacity for protein secretion, and generally recognized as safe (GRAS) status. In addition, as the metabolically dormant form of B. subtilis, its spores have attracted great interest due to their extreme resistance to many environmental stresses, which makes spores a novel platform for a variety of applications. In this review, we summarize both conventional and emerging applications of B. subtilis spores, with a focus on how their unique characteristics have led to innovative applications in many areas of technology, including generation of stable and recyclable enzymes, synthetic biology, drug delivery, and material sciences. Ultimately, this review hopes to inspire the scientific community to leverage interdisciplinary approaches using spores to address global concerns about food shortages, environmental protection, and health care. The bacterium Bacillus subtilis has long been an important subject for basic studies. However, this organism has also had industrial applications due to its easy genetic manipulation, favorable culturing characteristics for large‐scale fermentation, superior capacity for protein secretion, and generally recognized as safe (GRAS) status. In addition, as the metabolically dormant form of B. subtilis, its spores have attracted great interest due to their extreme resistance to many environmental stresses, which makes spores a novel platform for a variety of applications. In this review, we summarize both conventional and emerging applications of B. subtilis spores, with a focus on how their unique characteristics have led to innovative applications in many areas of technology, including generation of stable and recyclable enzymes, synthetic biology, drug delivery, and material sciences. Ultimately, this review hopes to inspire the scientific community to leverage interdisciplinary approaches using spores to address global concerns about food shortages, environmental protection, and health care. The bacterium has long been an important subject for basic studies. However, this organism has also had industrial applications due to its easy genetic manipulation, favorable culturing characteristics for large-scale fermentation, superior capacity for protein secretion, and generally recognized as safe (GRAS) status. In addition, as the metabolically dormant form of , its spores have attracted great interest due to their extreme resistance to many environmental stresses, which makes spores a novel platform for a variety of applications. In this review, we summarize both conventional and emerging applications of spores, with a focus on how their unique characteristics have led to innovative applications in many areas of technology, including generation of stable and recyclable enzymes, synthetic biology, drug delivery, and material sciences. Ultimately, this review hopes to inspire the scientific community to leverage interdisciplinary approaches using spores to address global concerns about food shortages, environmental protection, and health care. |
| Author | Li, Jiahe Al-Dossary, Amal Zhang, Xiaopei Setlow, Peter Hussain, Myer |
| Author_xml | – sequence: 1 givenname: Xiaopei surname: Zhang fullname: Zhang, Xiaopei organization: Department of Bioengineering, Northeastern University, Boston, Massachusetts, USA – sequence: 2 givenname: Amal surname: Al-Dossary fullname: Al-Dossary, Amal organization: Department of Biology, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia – sequence: 3 givenname: Myer surname: Hussain fullname: Hussain, Myer organization: Department of Bioengineering, Northeastern University, Boston, Massachusetts, USA – sequence: 4 givenname: Peter surname: Setlow fullname: Setlow, Peter organization: Department of Molecular Biology and Biophysics, UConn Health, Farmington, Connecticut, USA – sequence: 5 givenname: Jiahe orcidid: 0000-0002-9889-8546 surname: Li fullname: Li, Jiahe organization: Department of Bioengineering, Northeastern University, Boston, Massachusetts, USA |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/32631858$$D View this record in MEDLINE/PubMed |
| BookMark | eNptkctPGzEQxq2KqgTorWdkqRcOXRg_4tiXSgmiDwkEEnC2vI4XjBx7sXeR8t_XCQ-1qKexxr_59M18e2gnpugQ-kLgmBAqT-ZnF8dAQImGwgc0qS_ZTBkTO2gCoFRDKYddtFfKAwBwEPIT2mVUMCKncoKu5n0fvDWDT7Hg1OGFsT6EseAytoMPvuDrPmVXsI944dPg7H1MId2tsYlLPF8-mWjdEl-YwWVvQjlAH7ta3OeXuo9uf5zdnP5qzi9__j6dnzeWEzo0buacYoYwISWztFVcMWqmBpi0lnEFrVEtJaqVU9pBB5Jw0zJSu44ysIrto-_Puv3YrtzSujhkE3Sf_crktU7G639_or_Xd-lJzzgHCaIKHL0I5PQ4ujLolS_WhWCiS2PRlFNCQIDYoF_foQ9pzLGuVynOxWxGBVTq8G9Hb1Zej10B-gzYnErJrtPWD9vLV4M-aAJ6k6iuieptoppuVL-9G3rV_S_-B9rEoMM |
| CitedBy_id | crossref_primary_10_1007_s12602_022_09909_5 crossref_primary_10_1016_j_jenvman_2022_116380 crossref_primary_10_1080_07388551_2021_1888069 crossref_primary_10_1016_j_biortech_2021_125854 crossref_primary_10_1002_jsfa_13140 crossref_primary_10_1016_j_biocontrol_2024_105572 crossref_primary_10_3390_microorganisms12030436 crossref_primary_10_3389_fimmu_2022_1012301 crossref_primary_10_3389_fpls_2024_1287184 crossref_primary_10_3389_fnut_2023_1116982 crossref_primary_10_1016_j_scitotenv_2024_172967 crossref_primary_10_3390_app142411999 crossref_primary_10_1039_D2TB00717G crossref_primary_10_3390_plants12051024 crossref_primary_10_1007_s00253_023_12900_x crossref_primary_10_1186_s44330_024_00012_5 crossref_primary_10_1007_s10904_024_03264_4 crossref_primary_10_3389_frspt_2023_1181843 crossref_primary_10_3390_ijms23063405 crossref_primary_10_1007_s00253_022_12319_w crossref_primary_10_1021_acssynbio_3c00628 crossref_primary_10_3389_fvets_2021_684818 crossref_primary_10_3390_bacteria3030017 crossref_primary_10_1016_j_cofs_2023_101122 crossref_primary_10_3390_ani13081383 crossref_primary_10_1186_s13068_025_02635_4 crossref_primary_10_3389_frfst_2023_1075789 crossref_primary_10_1002_jobm_202300614 crossref_primary_10_3390_molecules26041186 crossref_primary_10_1128_Spectrum_00754_21 crossref_primary_10_1016_j_cemconcomp_2021_104334 crossref_primary_10_1016_j_jwpe_2024_105789 crossref_primary_10_1051_bioconf_20236801011 crossref_primary_10_1016_j_jece_2025_115426 crossref_primary_10_3390_toxins16110478 crossref_primary_10_1016_j_jclepro_2022_131785 crossref_primary_10_1016_j_biotechadv_2023_108300 crossref_primary_10_1016_j_csbj_2023_02_007 crossref_primary_10_1080_17460913_2025_2480933 crossref_primary_10_1007_s00253_021_11289_9 crossref_primary_10_1021_acsbiomaterials_2c01209 crossref_primary_10_1016_j_aqrep_2024_102490 crossref_primary_10_3390_buildings15060943 crossref_primary_10_1016_j_ab_2023_115315 crossref_primary_10_1134_S1062359021150085 crossref_primary_10_3390_ddc3040044 crossref_primary_10_1016_j_tim_2022_03_003 crossref_primary_10_3389_fpls_2023_1205894 crossref_primary_10_3390_toxins15050308 crossref_primary_10_1142_S179398442440004X |
| Cites_doi | 10.1039/C5RA20858K 10.1016/j.cej.2017.10.143 10.1038/s41392-017-0004-3 10.1371/journal.pone.0191627 10.1099/jmm.0.057372-0 10.1128/9781555819323.ch10 10.3390/resources3040614 10.1021/acs.estlett.6b00064 10.1021/acssuschemeng.9b03257 10.1128/AEM.02938-19 10.4014/jmb.1608.08026 10.1186/s12934-019-1094-0 10.1038/nmat4930 10.1128/JB.05154-11 10.1021/acs.jafc.6b03347 10.1146/annurev-micro-090816-093558 10.1128/IAI.00786-13 10.1038/nnano.2013.290 10.1128/AEM.01489-06 10.1128/AEM.05219-11 10.1007/s10068-015-0228-3 10.1016/j.molliq.2018.10.134 10.4014/jmb.1807.06066 10.1016/j.nbt.2011.05.007 10.1128/JB.05310-11 10.1128/aem.68.5.2344-2352.2002 10.1016/s0168-1605(02)00311-2 10.1111/j.1365-2672.2005.02736.x 10.1016/j.scitotenv.2019.135007 10.1002/pmic.201100003 10.1111/jam.13421 10.1128/AEM.00956-19 10.1111/mmi.14194 10.1007/s00018-009-0067-6 10.1016/j.hydromet.2016.01.035 10.1016/j.jconrel.2016.02.014 10.1128/AEM.01103-10 10.3109/1061186X.2013.778262 10.1155/2018/2568038 10.3390/su12020696 10.1016/j.biotechadv.2018.02.016 10.1007/s13201-018-0661-6 10.1002/anie.201708459 10.1128/microbiolspec.TBS-0011-2012 10.1007/s10439-016-1611-9 10.1016/j.jbiotec.2016.04.027 10.1016/j.vaccine.2006.09.013 10.1089/3dp.2015.0033 10.1016/j.jconrel.2017.12.013 10.1007/s12010-018-2855-7 10.1016/j.compositesb.2016.11.034 10.1016/j.vaccine.2012.03.016 10.1002/jobm.201600203 10.1186/s12934-019-1152-7 10.1016/j.cub.2010.03.060 10.1002/eji.200636875 10.3390/polym3031377 10.1007/s00284-013-0440-4 10.1016/B978-0-12-391500-9.00006-1 10.1093/femsle/fny190 10.1002/adsc.200700082 10.1016/j.mattod.2018.12.039 10.1002/slct.201902206 10.1128/AEM.64.4.1385-1389.1998 10.1038/s41598-019-49002-6 10.1016/j.drudis.2016.04.003 10.1111/1574-6968.12546 10.3389/fmicb.2017.01490 10.1007/s00253-014-5897-y 10.3389/fimmu.2018.00346 10.1016/j.vaccine.2003.09.031 10.1111/j.1467-7652.2011.00595.x 10.1016/j.vaccine.2009.10.127 10.1128/aem.69.8.4901-4909.2003 10.1128/JB.00321-19 10.1016/j.biotechadv.2015.02.014 10.1007/s00253-020-10348-x 10.1128/9781555819972.ch2 10.1038/s41589-019-0412-5 10.1186/s12934-017-0765-y 10.1002/adma.201704847 10.1111/jam.14192 10.1080/14786419.2014.939083 10.1007/s00792-015-0755-0 10.1186/s13765-019-0448-y 10.1128/JB.183.21.6294-6301.2001 10.1128/microbiolspec.TBS-0023-2016 10.1128/JB.188.7.2692-2700.2006 10.1371/journal.pone.0175255 10.1128/JB.01103-09 10.1016/j.resmic.2010.07.008 10.1186/s13071-018-2757-0 10.1177/1535370219881129 10.1007/s00284-019-01723-7 10.1016/j.fsi.2018.12.060 10.1021/acssynbio.7b00285 10.1007/s10658-011-9905-0 10.1016/j.pestbp.2017.05.008 |
| ContentType | Journal Article |
| Copyright | Copyright © 2020 American Society for Microbiology. Copyright American Society for Microbiology Sep 2020 Copyright © 2020 American Society for Microbiology. 2020 American Society for Microbiology |
| Copyright_xml | – notice: Copyright © 2020 American Society for Microbiology. – notice: Copyright American Society for Microbiology Sep 2020 – notice: Copyright © 2020 American Society for Microbiology. 2020 American Society for Microbiology |
| DBID | AAYXX CITATION CGR CUY CVF ECM EIF NPM 7QL 7QO 7SN 7SS 7ST 7T7 7TM 7U9 8FD C1K FR3 H94 M7N P64 RC3 SOI 7X8 5PM |
| DOI | 10.1128/AEM.01096-20 |
| DatabaseName | CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed Bacteriology Abstracts (Microbiology B) Biotechnology Research Abstracts Ecology Abstracts Entomology Abstracts (Full archive) Environment Abstracts Industrial and Applied Microbiology Abstracts (Microbiology A) Nucleic Acids Abstracts Virology and AIDS Abstracts Technology Research Database Environmental Sciences and Pollution Management Engineering Research Database AIDS and Cancer Research Abstracts Algology Mycology and Protozoology Abstracts (Microbiology C) Biotechnology and BioEngineering Abstracts Genetics Abstracts Environment Abstracts MEDLINE - Academic PubMed Central (Full Participant titles) |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) Virology and AIDS Abstracts Technology Research Database Nucleic Acids Abstracts Ecology Abstracts Biotechnology and BioEngineering Abstracts Environmental Sciences and Pollution Management Entomology Abstracts Genetics Abstracts Biotechnology Research Abstracts Bacteriology Abstracts (Microbiology B) Algology Mycology and Protozoology Abstracts (Microbiology C) AIDS and Cancer Research Abstracts Engineering Research Database Industrial and Applied Microbiology Abstracts (Microbiology A) Environment Abstracts MEDLINE - Academic |
| DatabaseTitleList | CrossRef MEDLINE - Academic Virology and AIDS Abstracts MEDLINE |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Economics Engineering Biology |
| DocumentTitleAlternate | Minireview |
| EISSN | 1098-5336 |
| ExternalDocumentID | PMC7440806 32631858 10_1128_AEM_01096_20 |
| Genre | Research Support, Non-U.S. Gov't Journal Article Review |
| GrantInformation_xml | – fundername: ; grantid: W81XWH18PRMRPDA |
| GroupedDBID | --- -~X 0R~ 23M 2WC 39C 4.4 53G 5GY 5RE 5VS 6J9 85S AAGFI AAYXX AAZTW ABOGM ABPPZ ACBTR ACGFO ACIWK ACNCT ACPRK ADBBV ADUKH AENEX AFRAH AGVNZ ALMA_UNASSIGNED_HOLDINGS AOIJS BAWUL BKOMP BTFSW CITATION CS3 D0L DIK E.- E3Z EBS F5P GX1 H13 HYE HZ~ K-O KQ8 L7B O9- P2P PQQKQ RHI RNS RPM RSF RXW TAE TN5 TR2 TWZ UHB W8F WH7 WOQ X6Y ~02 ~KM CGR CUY CVF ECM EIF NPM OK1 RHF UCJ Z5M 7QL 7QO 7SN 7SS 7ST 7T7 7TM 7U9 8FD C1K FR3 H94 M7N P64 RC3 SOI 7X8 5PM |
| ID | FETCH-LOGICAL-c412t-e7ee93a136883c2b94932a5a038cc3490ba9b219b852f0f0814ab31ba9e230c93 |
| ISSN | 0099-2240 1098-5336 |
| IngestDate | Thu Aug 21 14:09:52 EDT 2025 Fri Jul 11 13:09:23 EDT 2025 Mon Jun 30 10:22:42 EDT 2025 Wed Feb 19 02:28:45 EST 2025 Thu Apr 24 23:12:14 EDT 2025 Tue Jul 01 04:29:19 EDT 2025 |
| IsDoiOpenAccess | false |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 17 |
| Keywords | biotechnology endospores material sciences Bacillus subtilis |
| Language | English |
| License | Copyright © 2020 American Society for Microbiology. All Rights Reserved. |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-LOGICAL-c412t-e7ee93a136883c2b94932a5a038cc3490ba9b219b852f0f0814ab31ba9e230c93 |
| Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 14 ObjectType-Review-3 content type line 23 Citation Zhang X, Al-Dossary A, Hussain M, Setlow P, Li J. 2020. Applications of Bacillus subtilis spores in biotechnology and advanced materials. Appl Environ Microbiol 86:e01096-20. https://doi.org/10.1128/AEM.01096-20. |
| ORCID | 0000-0002-9889-8546 |
| OpenAccessLink | https://www.ncbi.nlm.nih.gov/pmc/articles/7440806 |
| PMID | 32631858 |
| PQID | 2444677260 |
| PQPubID | 42251 |
| ParticipantIDs | pubmedcentral_primary_oai_pubmedcentral_nih_gov_7440806 proquest_miscellaneous_2421106066 proquest_journals_2444677260 pubmed_primary_32631858 crossref_citationtrail_10_1128_AEM_01096_20 crossref_primary_10_1128_AEM_01096_20 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 20200818 |
| PublicationDateYYYYMMDD | 2020-08-18 |
| PublicationDate_xml | – month: 8 year: 2020 text: 20200818 day: 18 |
| PublicationDecade | 2020 |
| PublicationPlace | United States |
| PublicationPlace_xml | – name: United States – name: Washington – name: 1752 N St., N.W., Washington, DC |
| PublicationTitle | Applied and environmental microbiology |
| PublicationTitleAlternate | Appl Environ Microbiol |
| PublicationYear | 2020 |
| Publisher | American Society for Microbiology |
| Publisher_xml | – name: American Society for Microbiology |
| References | e_1_3_2_28_2 e_1_3_2_20_2 e_1_3_2_43_2 e_1_3_2_62_2 e_1_3_2_85_2 Rohini I (e_1_3_2_78_2) 2018; 9 e_1_3_2_47_2 e_1_3_2_66_2 e_1_3_2_89_2 e_1_3_2_100_2 e_1_3_2_81_2 e_1_3_2_16_2 e_1_3_2_7_2 e_1_3_2_39_2 e_1_3_2_54_2 e_1_3_2_31_2 e_1_3_2_73_2 e_1_3_2_12_2 e_1_3_2_58_2 e_1_3_2_96_2 e_1_3_2_3_2 e_1_3_2_35_2 e_1_3_2_77_2 e_1_3_2_92_2 e_1_3_2_50_2 e_1_3_2_48_2 e_1_3_2_29_2 e_1_3_2_40_2 e_1_3_2_86_2 e_1_3_2_21_2 e_1_3_2_63_2 e_1_3_2_44_2 e_1_3_2_25_2 e_1_3_2_67_2 e_1_3_2_82_2 e_1_3_2_17_2 e_1_3_2_59_2 e_1_3_2_6_2 e_1_3_2_32_2 e_1_3_2_51_2 e_1_3_2_74_2 e_1_3_2_13_2 e_1_3_2_36_2 e_1_3_2_55_2 e_1_3_2_97_2 e_1_3_2_2_2 e_1_3_2_93_2 e_1_3_2_70_2 e_1_3_2_26_2 e_1_3_2_49_2 e_1_3_2_41_2 e_1_3_2_64_2 e_1_3_2_87_2 e_1_3_2_22_2 e_1_3_2_45_2 e_1_3_2_68_2 e_1_3_2_60_2 e_1_3_2_83_2 e_1_3_2_9_2 e_1_3_2_37_2 e_1_3_2_18_2 e_1_3_2_75_2 e_1_3_2_10_2 e_1_3_2_52_2 e_1_3_2_5_2 e_1_3_2_33_2 e_1_3_2_79_2 e_1_3_2_14_2 e_1_3_2_56_2 e_1_3_2_98_2 e_1_3_2_94_2 e_1_3_2_71_2 e_1_3_2_90_2 Nicks TB (e_1_3_2_24_2) 2019 e_1_3_2_27_2 e_1_3_2_65_2 e_1_3_2_42_2 e_1_3_2_84_2 e_1_3_2_23_2 e_1_3_2_69_2 e_1_3_2_46_2 e_1_3_2_88_2 e_1_3_2_61_2 e_1_3_2_80_2 e_1_3_2_101_2 e_1_3_2_15_2 e_1_3_2_38_2 e_1_3_2_8_2 e_1_3_2_19_2 e_1_3_2_30_2 e_1_3_2_53_2 e_1_3_2_76_2 e_1_3_2_99_2 e_1_3_2_11_2 e_1_3_2_34_2 e_1_3_2_57_2 e_1_3_2_95_2 e_1_3_2_4_2 e_1_3_2_91_2 e_1_3_2_72_2 |
| References_xml | – ident: e_1_3_2_81_2 doi: 10.1039/C5RA20858K – ident: e_1_3_2_83_2 doi: 10.1016/j.cej.2017.10.143 – ident: e_1_3_2_62_2 doi: 10.1038/s41392-017-0004-3 – ident: e_1_3_2_51_2 doi: 10.1371/journal.pone.0191627 – ident: e_1_3_2_47_2 doi: 10.1099/jmm.0.057372-0 – ident: e_1_3_2_9_2 doi: 10.1128/9781555819323.ch10 – ident: e_1_3_2_84_2 doi: 10.3390/resources3040614 – ident: e_1_3_2_87_2 doi: 10.1021/acs.estlett.6b00064 – ident: e_1_3_2_28_2 doi: 10.1021/acssuschemeng.9b03257 – ident: e_1_3_2_61_2 doi: 10.1128/AEM.02938-19 – ident: e_1_3_2_44_2 doi: 10.4014/jmb.1608.08026 – ident: e_1_3_2_60_2 doi: 10.1186/s12934-019-1094-0 – ident: e_1_3_2_74_2 doi: 10.1038/nmat4930 – ident: e_1_3_2_93_2 doi: 10.1128/JB.05154-11 – ident: e_1_3_2_27_2 doi: 10.1021/acs.jafc.6b03347 – ident: e_1_3_2_4_2 doi: 10.1146/annurev-micro-090816-093558 – ident: e_1_3_2_97_2 doi: 10.1128/IAI.00786-13 – ident: e_1_3_2_73_2 doi: 10.1038/nnano.2013.290 – ident: e_1_3_2_35_2 doi: 10.1128/AEM.01489-06 – ident: e_1_3_2_12_2 doi: 10.1128/AEM.05219-11 – ident: e_1_3_2_34_2 doi: 10.1007/s10068-015-0228-3 – ident: e_1_3_2_86_2 doi: 10.1016/j.molliq.2018.10.134 – ident: e_1_3_2_49_2 doi: 10.4014/jmb.1807.06066 – ident: e_1_3_2_95_2 doi: 10.1016/j.nbt.2011.05.007 – ident: e_1_3_2_19_2 doi: 10.1128/JB.05310-11 – ident: e_1_3_2_65_2 doi: 10.1128/aem.68.5.2344-2352.2002 – ident: e_1_3_2_11_2 doi: 10.1016/s0168-1605(02)00311-2 – volume-title: Anchoring proteins for spore-display of enzymes are best selected using surface availability of the anchoring terminus as opposed to loading density of the anchor protein year: 2019 ident: e_1_3_2_24_2 – ident: e_1_3_2_5_2 doi: 10.1111/j.1365-2672.2005.02736.x – ident: e_1_3_2_101_2 doi: 10.1016/j.scitotenv.2019.135007 – ident: e_1_3_2_20_2 doi: 10.1002/pmic.201100003 – ident: e_1_3_2_79_2 doi: 10.1111/jam.13421 – ident: e_1_3_2_88_2 doi: 10.1128/AEM.00956-19 – ident: e_1_3_2_7_2 doi: 10.1111/mmi.14194 – ident: e_1_3_2_15_2 doi: 10.1007/s00018-009-0067-6 – ident: e_1_3_2_82_2 doi: 10.1016/j.hydromet.2016.01.035 – ident: e_1_3_2_43_2 doi: 10.1016/j.jconrel.2016.02.014 – ident: e_1_3_2_17_2 doi: 10.1128/AEM.01103-10 – ident: e_1_3_2_66_2 doi: 10.3109/1061186X.2013.778262 – ident: e_1_3_2_89_2 doi: 10.1155/2018/2568038 – ident: e_1_3_2_75_2 doi: 10.3390/su12020696 – ident: e_1_3_2_54_2 doi: 10.1016/j.biotechadv.2018.02.016 – ident: e_1_3_2_90_2 doi: 10.1007/s13201-018-0661-6 – ident: e_1_3_2_57_2 doi: 10.1002/anie.201708459 – ident: e_1_3_2_16_2 doi: 10.1128/microbiolspec.TBS-0011-2012 – ident: e_1_3_2_70_2 doi: 10.1007/s10439-016-1611-9 – ident: e_1_3_2_98_2 doi: 10.1016/j.jbiotec.2016.04.027 – ident: e_1_3_2_50_2 doi: 10.1016/j.vaccine.2006.09.013 – ident: e_1_3_2_71_2 doi: 10.1089/3dp.2015.0033 – ident: e_1_3_2_64_2 doi: 10.1016/j.jconrel.2017.12.013 – ident: e_1_3_2_32_2 doi: 10.1007/s12010-018-2855-7 – ident: e_1_3_2_67_2 doi: 10.1016/j.compositesb.2016.11.034 – ident: e_1_3_2_100_2 doi: 10.1016/j.vaccine.2012.03.016 – ident: e_1_3_2_30_2 doi: 10.1002/jobm.201600203 – ident: e_1_3_2_33_2 doi: 10.1186/s12934-019-1152-7 – ident: e_1_3_2_8_2 doi: 10.1016/j.cub.2010.03.060 – ident: e_1_3_2_99_2 doi: 10.1002/eji.200636875 – ident: e_1_3_2_63_2 doi: 10.3390/polym3031377 – ident: e_1_3_2_37_2 doi: 10.1007/s00284-013-0440-4 – ident: e_1_3_2_36_2 doi: 10.1016/B978-0-12-391500-9.00006-1 – ident: e_1_3_2_56_2 doi: 10.1093/femsle/fny190 – ident: e_1_3_2_22_2 doi: 10.1002/adsc.200700082 – ident: e_1_3_2_69_2 doi: 10.1016/j.mattod.2018.12.039 – ident: e_1_3_2_76_2 doi: 10.1002/slct.201902206 – ident: e_1_3_2_41_2 doi: 10.1128/AEM.64.4.1385-1389.1998 – ident: e_1_3_2_80_2 doi: 10.1038/s41598-019-49002-6 – ident: e_1_3_2_58_2 doi: 10.1016/j.drudis.2016.04.003 – ident: e_1_3_2_52_2 doi: 10.1111/1574-6968.12546 – ident: e_1_3_2_3_2 doi: 10.3389/fmicb.2017.01490 – ident: e_1_3_2_23_2 doi: 10.1007/s00253-014-5897-y – ident: e_1_3_2_45_2 doi: 10.3389/fimmu.2018.00346 – ident: e_1_3_2_48_2 doi: 10.1016/j.vaccine.2003.09.031 – ident: e_1_3_2_42_2 doi: 10.1111/j.1467-7652.2011.00595.x – volume: 9 start-page: 230 year: 2018 ident: e_1_3_2_78_2 article-title: Effect of bateria subtilis on conrete substituted fully and partially with demolition wastes publication-title: Int J Civ Eng – ident: e_1_3_2_55_2 doi: 10.1016/j.vaccine.2009.10.127 – ident: e_1_3_2_77_2 doi: 10.1128/aem.69.8.4901-4909.2003 – ident: e_1_3_2_25_2 doi: 10.1128/JB.00321-19 – ident: e_1_3_2_21_2 doi: 10.1016/j.biotechadv.2015.02.014 – ident: e_1_3_2_13_2 doi: 10.1007/s00253-020-10348-x – ident: e_1_3_2_10_2 doi: 10.1128/9781555819972.ch2 – ident: e_1_3_2_72_2 doi: 10.1038/s41589-019-0412-5 – ident: e_1_3_2_46_2 doi: 10.1186/s12934-017-0765-y – ident: e_1_3_2_68_2 doi: 10.1002/adma.201704847 – ident: e_1_3_2_2_2 doi: 10.1111/jam.14192 – ident: e_1_3_2_38_2 doi: 10.1080/14786419.2014.939083 – ident: e_1_3_2_26_2 doi: 10.1007/s00792-015-0755-0 – ident: e_1_3_2_29_2 doi: 10.1186/s13765-019-0448-y – ident: e_1_3_2_14_2 doi: 10.1128/JB.183.21.6294-6301.2001 – ident: e_1_3_2_6_2 doi: 10.1128/microbiolspec.TBS-0023-2016 – ident: e_1_3_2_94_2 doi: 10.1128/JB.188.7.2692-2700.2006 – ident: e_1_3_2_85_2 doi: 10.1371/journal.pone.0175255 – ident: e_1_3_2_91_2 doi: 10.1128/JB.01103-09 – ident: e_1_3_2_92_2 doi: 10.1016/j.resmic.2010.07.008 – ident: e_1_3_2_96_2 doi: 10.1186/s13071-018-2757-0 – ident: e_1_3_2_59_2 doi: 10.1177/1535370219881129 – ident: e_1_3_2_31_2 doi: 10.1007/s00284-019-01723-7 – ident: e_1_3_2_53_2 doi: 10.1016/j.fsi.2018.12.060 – ident: e_1_3_2_18_2 doi: 10.1021/acssynbio.7b00285 – ident: e_1_3_2_40_2 doi: 10.1007/s10658-011-9905-0 – ident: e_1_3_2_39_2 doi: 10.1016/j.pestbp.2017.05.008 |
| SSID | ssj0004068 |
| Score | 2.559079 |
| SecondaryResourceType | review_article |
| Snippet | The bacterium
Bacillus subtilis
has long been an important subject for basic studies. However, this organism has also had industrial applications due to its... The bacterium has long been an important subject for basic studies. However, this organism has also had industrial applications due to its easy genetic... The bacterium Bacillus subtilis has long been an important subject for basic studies. However, this organism has also had industrial applications due to its... |
| SourceID | pubmedcentral proquest pubmed crossref |
| SourceType | Open Access Repository Aggregation Database Index Database Enrichment Source |
| SubjectTerms | Bacillus subtilis Biotechnology Construction Materials - microbiology Drug delivery Drug delivery systems Environmental protection Environmental stress Fermentation Industrial applications Minireview Spores Spores, Bacterial |
| Title | Applications of Bacillus subtilis Spores in Biotechnology and Advanced Materials |
| URI | https://www.ncbi.nlm.nih.gov/pubmed/32631858 https://www.proquest.com/docview/2444677260 https://www.proquest.com/docview/2421106066 https://pubmed.ncbi.nlm.nih.gov/PMC7440806 |
| Volume | 86 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3fj5QwEG7WM8bzweiqJ3qamujThhMKC-URdS8X3T012U32jZRuiSTIXgQe9K93Bsovb01OXwgpDRDmo_2m0_mGkNdceDBJ2YGZyJ1nusA4zCC2EhPrQbo7z4-Zwmzk1aV3sXE_bufbyWQ52LVUlfGZ_HUwr-R_rAptYFfMkv0Hy3Y3hQY4B_vCESwMxxvZOBxEn5H1vRMyzbKqmBVVXKZZWsywiHm95QqLTpbdMnodMgjb8P9KlM3bDplqS0-x5yAbDpNN0l686dq68zYV-yuVdjjKzA8wDYsmWB9-F1mPI2huBAyw8ES30qPKrAk39TuH9aIEq7fEjcZRlCkFJqlVrg-06cFX62BrkPmHB3WGiQrhYnWGcTzPZFY_ebUB-8vP0flmuYzWi-36FrnNwGnAehafvg604y2dGKlfo02DYPzt8N5jgnLN6_hz8-yAjawfkPvajaBhg4mHZKLyKbnTFBb9OSV323zzYkruDSQnH5EvQ8zQfUJbzNAWM7TBDE1zOsIMBSTQFjO0w8xjsjlfrN9fmLqqhildm5Wm8pUKHGE7HueOZHHgAoUXc2E5XErHDaxYBDHMYzGfs8RKgDK6InZsaFXgrsrAeUKO8n2unhKaiGRnu3NHcF9iCWsOVCewcOcct7hMfIPM2k8ZSS05j5VPsqh2PRmP4MNH9YePmGWQN13vq0Zq5S_9TlurRPpnLCJgqTDl--CdG-RVdxmGSox_iVztK-yDqx3osRvkpDFi9yDwYlBHgBvEH5m364Ay7OMrefqtlmNHiU1uec9u8Nzn5Lj_W07JUfmjUi-A1JbxyxqrvwGrcKON |
| linkProvider | Colorado Alliance of Research Libraries |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Applications+of+Bacillus+subtilis+Spores+in+Biotechnology+and+Advanced+Materials&rft.jtitle=Applied+and+environmental+microbiology&rft.au=Zhang%2C+Xiaopei&rft.au=Al-Dossary%2C+Amal&rft.au=Hussain%2C+Myer&rft.au=Setlow%2C+Peter&rft.date=2020-08-18&rft.issn=1098-5336&rft.eissn=1098-5336&rft.volume=86&rft.issue=17&rft_id=info:doi/10.1128%2FAEM.01096-20&rft.externalDBID=NO_FULL_TEXT |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0099-2240&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0099-2240&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0099-2240&client=summon |