Polyvinyl-Pyrrolidone-Coated Silver Nanoparticles—The Colloidal, Chemical, and Biological Consequences of Steric Stabilization under Biorelevant Conditions

• Published in: International journal of molecular sciences Vol. 22; no. 16; p. 8673
• Main Authors: Rónavári, Andrea, Bélteky, Péter, Boka, Eszter, Zakupszky, Dalma, Igaz, Nóra, Szerencsés, Bettina, Pfeiffer, Ilona, Kónya, Zoltán, Kiricsi, Mónika
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 12.08.2021; MDPI
• Subjects: Anti-Infective Agents - chemistry; Anti-Infective Agents - pharmacology; Antimicrobial agents; Antineoplastic Agents - chemistry; Antineoplastic Agents - pharmacology; Biological activity; Cell Line, Tumor; Cell Survival - drug effects; Dynamic Light Scattering; Gram-Negative Bacteria - drug effects; Gram-Positive Bacteria - drug effects; HeLa Cells; Humans; Hydrogen-Ion Concentration; Metal Nanoparticles; Microbial Sensitivity Tests; Microscopy, Electron, Transmission; Molecular weight; Morphology; Nanomaterials; Nanoparticles; Particle size; Polymers; Povidone - chemistry; Silver; Silver - chemistry; Silver - pharmacology; chemical stability; steric stabilization; anticancer activity; antimicrobial activity; aggregation behavior; cytotoxicity

(1) Background: Several properties of silver nanoparticles (AgNPs), such as cytotoxic, anticancer, and antimicrobial activities, have been subjects of intense research; however, important aspects such as nanoparticle aggregation are generally neglected, although a decline in colloidal stability lead...