Dynamic changes in cis-regulatory occupancy by Six1 and its cooperative interactions with distinct cofactors drive lineage-specific gene expression programs during progressive differentiation of the auditory sensory epithelium - Li, Jun; Zhang, Ting; Ramakrishnan, Aarthi; Fritzsch, Bernd; Xu, Jinshu; Wong, Elaine Y M; Loh, Yong-Hwee Eddie; Ding, Jianqiang; Shen, Li; Xu, Pin-Xian (Nucleic acids research, 2020)
Keywords: Base Sequence; Cell Differentiation - genetics; Cell Lineage - genetics; Cell Polarity; Consensus Sequence; DNA - metabolism; Dual Specificity Phosphatase 6 - genetics; Dual Specificity Phosphatase 6 - metabolism; Enhancer Elements, Genetic - genetics; Epithelium - metabolism; Fibroblast Growth Factor 8 - genetics; Fibroblast Growth Factor 8 - metabolism; Gene Expression Regulation, Developmental; Gene regulation, Chromatin and Epigenetics; Genetic Loci; Genome; Hair Cells, Auditory - cytology; Hair Cells, Auditory - metabolism; Hair Cells, Auditory - ultrastructure; Homeodomain Proteins - metabolism; Humans; Multiprotein Complexes - metabolism; Nucleotide Motifs - genetics; Protein Binding; Signal Transduction - genetics