Basophil Activation Test Utility as a Diagnostic Tool in LTP Allergy

• Published in: International journal of molecular sciences Vol. 23; no. 9; p. 4979
• Main Authors: Cañas, José A., Pérez-Sánchez, Natalia, Lopera-Doblas, Leticia, Palomares, Francisca, Molina, Ana, Bartra, Joan, Torres, María J., Gómez, Francisca, Mayorga, Cristobalina
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 29.04.2022; MDPI
• Subjects: Allergens; Allergens - metabolism; Allergies; Anaphylaxis; Arachis; Basophil Degranulation Test - methods; Basophils; Flow cytometry; Food allergies; Food Hypersensitivity - diagnosis; Food Hypersensitivity - metabolism; Humans; Immunoglobulin E - metabolism; Patients; Principal components analysis; Urticaria; basophil activation test; diagnosis; nonspecific lipid transfer proteins; flow cytometry; Pru p 3

Plant-food allergy is an increasing problem, with nonspecific lipid transfer proteins (nsLTPs) triggering mild/severe reactions. Pru p 3 is the major sensitizer in LTP food allergy (FA). However, in vivo and in vitro diagnosis is hampered by the need for differentiating between asymptomatic sensitiz...