Prevalence of clinically significant liver disease within the general population, as defined by non-invasive markers of liver fibrosis: a systematic review

• Published in: The lancet. Gastroenterology & hepatology Vol. 2; no. 4; p. 288
• Main Authors: Harris, Rebecca, Harman, David J, Card, Timothy R, Aithal, Guruprasad P, Guha, Indra Neil
• Format: Journal Article
• Language: English
• Published: Netherlands 01.04.2017
• Subjects: Asymptomatic Diseases - epidemiology; Chronic Disease; Early Diagnosis; Humans; Liver Cirrhosis - diagnosis; Liver Cirrhosis - epidemiology; Liver Diseases - diagnosis; Liver Diseases - epidemiology; Liver Function Tests - methods; Mass Screening - methods; Prevalence; Risk Assessment; Risk Factors

As of 2016, there is no evidence-based pathway to stratify the risk of chronic liver disease in a general population setting. Non-invasive tests of liver fibrosis might provide a mechanism for earlier diagnosis. These tests have been extensively validated in the hospital setting but their performanc...