Adaptive Optical Two-Photon Fluorescence Microscopy Probes Cellular Organization of Ocular Lenses In Vivo

• Published in: Investigative ophthalmology & visual science Vol. 64; no. 7; p. 20
• Main Authors: Paidi, Santosh Kumar, Zhang, Qinrong, Yang, Yuhan, Xia, Chun-Hong, Ji, Na, Gong, Xiaohua
• Format: Journal Article
• Language: English
• Published: United States Association for Research in Vision and Ophthalmology 12.06.2023; The Association for Research in Vision and Ophthalmology
• Subjects: 60 APPLIED LIFE SCIENCES; Animals; Epithelial Cells; Eye; Lens; Lens, Crystalline; Mammals; Microscopy, Fluorescence; Ophthalmology; Photons

The mammalian ocular lens is an avascular multicellular organ that grows continuously throughout life. Traditionally, its cellular organization is investigated using dissected lenses, which eliminates in vivo environmental and structural support. Therefore, in vivo optical imaging methods for studyi...