Interpretation of α-synuclein UV absorption spectra in the peptide bond and the aromatic regions

• Published in: Journal of photochemistry and photobiology. B, Biology Vol. 212; p. 112022
• Main Author: Saraiva, Marco A.
• Format: Journal Article
• Language: English
• Published: Lausanne Elsevier B.V 01.11.2020; Elsevier BV
• Subjects: absorbance; Absorption; Absorption spectra; Agglomeration; Aggregation mechanism; Amino acids; Amyloid; Aromatic region; Hydrogen bonding; Ion concentration; Light scattering; Peptide bond region; Peptides; Perturbation; pH effects; photobiology; photochemistry; Proteins; Residues; spectroscopy; Synuclein; Ultraviolet absorption; Ultraviolet radiation; UV absorption; α-Synuclein; Aggregation mechanism; α-Synuclein; UV absorption; Aromatic region; Peptide bond region

The interpretation of the UV absorption spectra of proteins was a matter of intense debate in the second half of the last century. The study of the spectroscopic characteristics of peptide bonds in proteins was then of particular interest but the absorption of a large number of peptide bonds in a pr...