Treatment of experimental allergic neuritis with prednisolone

• Published in: Canadian journal of neurological sciences Vol. 14; no. 1; p. 46
• Main Authors: Feasby, T E, Gilbert, J J, Hahn, A F, Lovgren, D S
• Format: Journal Article
• Language: English
• Published: England 01.02.1987
• Subjects: Animals; Drug Administration Schedule; Male; Neuritis, Autoimmune, Experimental - drug therapy; Neuritis, Autoimmune, Experimental - pathology; Prednisolone - therapeutic use; Rats; Rats, Inbred Lew; Sciatic Nerve - drug effects; Sciatic Nerve - pathology; Spinal Nerve Roots - drug effects; Spinal Nerve Roots - pathology; Time Factors

Experimental allergic neuritis (EAN) in Lewis rats was treated with prednisolone given prophylactically or therapeutically. Rats treated from the time of immunization with myelin or after the establishment of clinical disease improved more rapidly than controls. Treatment at the onset of clinical si...