Roles and regulatory mechanisms of miR-30b in cancer, cardiovascular disease, and metabolic disorders (Review)

• Published in: Experimental and therapeutic medicine Vol. 21; no. 1; p. 44
• Main Authors: Zhang, Qing, Liu, Shousheng, Zhang, Jie, Ma, Xuefeng, Dong, Mengzhen, Sun, Baokai, Xin, Yongning
• Format: Journal Article
• Language: English
• Published: Greece Spandidos Publications 01.01.2021; Spandidos Publications UK Ltd; D.A. Spandidos
• Subjects: Angiogenesis; Apoptosis; Autophagy; Biomarkers; Bladder cancer; Cancer; Cardiovascular diseases; Cell cycle; Cell growth; Colorectal cancer; Development and progression; Diagnosis; Drug dosages; Drug resistance; Gastric cancer; Gene expression; Genetic aspects; Growth factors; Health aspects; Kinases; Liver cancer; Lung cancer; Medical prognosis; Metabolic diseases; Metabolic disorders; Metastasis; MicroRNA; MicroRNAs; Mortality; Physiology; Review; Roles; Stem cells; Tumors; China; miRNA-30b; metabolism; cardiovascular diseases; biomarker; tumor

MicroRNAs (miRNAs) are non-coding RNAs 21-23 nucleotides in length that regulate gene expression, and thereby modulate signaling pathways and protein synthesis in both physiological and pathogenic processes. miR-30b inhibits cell proliferation, migration, invasion and epithelial-mesenchymal transfor...