Functional characteristics of the frontal cortex during the verbal fluency task in subthreshold depression: A fNIRS study

• Published in: Journal of affective disorders Vol. 384; pp. 144 - 150
• Main Authors: Liu, Jingxuan, Hu, Yuhan, Zong, Boyi, Wang, Shiyu, Zheng, Yifan, Guo, Dongxi, Shi, Chengchao, Cai, Ruijin, Li, Lin
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.09.2025
• Subjects: Adult; Brain Mapping; Depression - physiopathology; Depressive Disorder, Major - physiopathology; Female; fNIRS; Frontal cortex; Frontal Lobe - physiopathology; Graph theory; Humans; Oxyhemoglobins - metabolism; Prefrontal Cortex - physiopathology; Psychiatric/Mental Health; Spectroscopy, Near-Infrared; Subthreshold depression; Verbal Behavior - physiology; Verbal fluency task; Young Adult; Verbal fluency task; Graph theory; fNIRS; Frontal cortex; Subthreshold depression

Subthreshold depression (SD), a recognized prodromal stage and major risk factor for major depressive disorder (MDD). Dysfunction of the frontal lobe is associated with the emergence and progression of depression. This study aims to systematically examine the functional characteristics of the fronta...