Identification of the Gene Repertoire of the IMD Pathway and Expression of Antimicrobial Peptide Genes in Several Tissues and Hemolymph of the Cockroach Blattella germanica

• Published in: International journal of molecular sciences Vol. 23; no. 15; p. 8444
• Main Authors: Zuber, Leo, Domínguez-Santos, Rebeca, García-Ferris, Carlos, Silva, Francisco J.
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 30.07.2022; MDPI
• Subjects: Animals; Antimicrobial agents; Antimicrobial Peptides; Bacteria; Blattellidae - genetics; Cockroaches; Exocrine glands; Female; Flavobacteriaceae; Gene expression; Genomes; Genomics; Gram-positive bacteria; Hemolymph; Homeostasis; Immune response; Insects; Legumes; Metabolism; Microbiota; Pathogens; Peptides; antimicrobial peptides (AMPs); innate immune response; Blattella germanica; symbiosis; transcriptome; IMD pathway

Antimicrobial peptide (AMP) genes, triggered by Toll and IMD pathways, are essential components of the innate immune system in the German cockroach Blattella germanica. Besides their role in killing pathogenic bacteria, AMPs could be involved in controlling its symbiotic systems (endosymbiont and mi...