Elevated levels of vitamin B12 and folate in vertically infected children with HIV-1

• Published in: AIDS (London) Vol. 23; no. 3; pp. 403 - 407
• Main Authors: MALIK, Zainab A, ABADI, Jacobo, SANSARY, Jorge, ROSENBERG, Michael
• Format: Journal Article
• Language: English
• Published: Hagerstown, MD Lippincott Williams & Wilkins 28.01.2009
• Subjects: Adolescent; AIDS/HIV; Anti-HIV Agents - therapeutic use; Antibiotics. Antiinfectious agents. Antiparasitic agents; Antiviral agents; Biological and medical sciences; CD4 Lymphocyte Count; Child; Cross-Sectional Studies; Female; Folic Acid - blood; Folic Acid Deficiency - virology; HIV Infections - blood; HIV Infections - complications; HIV Infections - drug therapy; HIV Infections - transmission; HIV-1; Human immunodeficiency virus 1; Human viral diseases; Humans; Immunodeficiencies; Immunodeficiencies. Immunoglobulinopathies; Immunopathology; Infectious Disease Transmission, Vertical; Infectious diseases; Male; Medical sciences; Pharmacology. Drug treatments; Retrospective Studies; Viral diseases; Viral diseases of the lymphoid tissue and the blood. Aids; Viral Load; Vitamin B 12 - blood; Vitamin B 12 Deficiency - virology; Pediatrics; Antiretroviral agent; HIV-1 virus; antiretroviral therapy; Vitamin; Maternal diseases; Microbiological investigation; cobalamin; Reverse transcriptase inhibitor; protease inhibitors; Antiviral; nutrition/ wasting; vitamin B12; Viral load; Child; Human; Immunopathology; Hematology; Nutrition; Weight loss; Retroviridae; AIDS; Immune deficiency; Lentivirus; Cyanocobalamin; Feeding; Infection; Virus; Chemotherapy; folate; reverse transcriptase inhibitors; Treatment; Denutrition; Viral disease; Vertical transmission; Human immunodeficiency virus; Protease inhibitor

Neurologic and hematologic abnormalities are common in HIV-infected children and may be related to concomitant deficiencies in serum B12 and folate, which are highly prevalent in HIV-infected adults. We sought to determine the prevalence of B12 and folate deficiencies in HIV-infected children in the...