Opioid Release after High-Intensity Interval Training in Healthy Human Subjects

• Published in: Neuropsychopharmacology (New York, N.Y.) Vol. 43; no. 2; pp. 246 - 254
• Main Authors: Saanijoki, Tiina, Tuominen, Lauri, Tuulari, Jetro J, Nummenmaa, Lauri, Arponen, Eveliina, Kalliokoski, Kari, Hirvonen, Jussi
• Format: Journal Article
• Language: English
• Published: England Nature Publishing Group 01.01.2018
• Subjects: Affect - physiology; Analgesics, Opioid - metabolism; Cerebral Cortex - diagnostic imaging; Cerebral Cortex - metabolism; Cortex (cingulate); Emotions; Exercise; Exercise - physiology; Fentanyl - analogs & derivatives; Fentanyl - metabolism; Gyrus Cinguli - diagnostic imaging; Gyrus Cinguli - metabolism; Healthy Volunteers; High-Intensity Interval Training; Hippocampus - diagnostic imaging; Hippocampus - metabolism; Human subjects; Humans; Interval training; Male; Mood; Narcotics; Opioid receptors; Original; Pain; Physical training; Positron emission tomography; Positron-Emission Tomography - methods; Prefrontal Cortex - diagnostic imaging; Prefrontal Cortex - metabolism; Receptors, Opioid, mu - metabolism; Reinforcement; Thalamus; Thalamus - diagnostic imaging; Thalamus - metabolism; Young Adult

Central opioidergic mechanisms may modulate the positive effects of physical exercise such as mood elevation and stress reduction. How exercise intensity and concomitant effective changes affect central opioidergic responses is unknown. We studied the effects of acute physical exercise on the cerebr...