Garlic lowers blood pressure in hypertensive subjects, improves arterial stiffness and gut microbiota: A review and meta-analysis
Garlic supplements have shown effectiveness in reducing blood pressure in hypertensive patients, similarly to first-line standard anti-hypertensive medications. Kyolic garlic has also shown promise in improving cardiovascular health by reducing arterial stiffness, elevated cholesterol levels and blo...
Saved in:
| Published in | Experimental and therapeutic medicine Vol. 19; no. 2; pp. 1472 - 1478 |
|---|---|
| Main Author | |
| Format | Journal Article |
| Language | English |
| Published |
Greece
Spandidos Publications
01.02.2020
Spandidos Publications UK Ltd D.A. Spandidos |
| Subjects | |
| Online Access | Get full text |
| ISSN | 1792-0981 1792-1015 |
| DOI | 10.3892/etm.2019.8374 |
Cover
Loading…
| Abstract | Garlic supplements have shown effectiveness in reducing blood pressure in hypertensive patients, similarly to first-line standard anti-hypertensive medications. Kyolic garlic has also shown promise in improving cardiovascular health by reducing arterial stiffness, elevated cholesterol levels and blood 'stickiness'. In addition, the prebiotic properties in garlic increase gut microbial richness and diversity. This article systematically reviews previously published trials investigating the effects of garlic on blood pressure, and provides an updated meta-analysis of hypertensive participants. In addition, we summarise the findings of recent clinical trials investigating the effects of Kyolic aged garlic extract on arterial stiffness, and gut microbiota in hypertensive subjects. We searched online electronic databases, including PubMed and Google Scholar for randomised controlled trials (RCTs) published between 1955 and December, 2018 examining the effects of garlic on high blood pressure. The meta-analysis of 12 trials and 553 hypertensive participants confirmed that garlic supplements lower systolic blood pressure (SBP) by an average of 8.3±1.9 mmHg and diastolic blood pressure (DBP, n=8 trials, n=374 subjects) by 5.5±1.9 mmHg, similarly to standard anti-hypertensive medications. This reduction in blood pressure was associated with a 16-40% reduction in the risk of suffering from cardiovascular events. Additionally, this review summarises new evidence for the vitamin B12 status playing an important role in the responsiveness of blood pressure to garlic. Furthermore, Kyolic aged garlic extract significantly lowered central blood pressure, pulse pressure, pulse wave velocity and arterial stiffness, and improved the gut microbiota, evidenced by higher microbial richness and diversity, with a marked increase in the numbers of
and
species found following 3 months of supplementation. Thus, Kyolic aged garlic extract is considered to be highly tolerable with a high safety profile either as a stand-alone or adjunctive anti-hypertensive treatment, with multiple benefits for cardiovascular health. |
|---|---|
| AbstractList | Garlic supplements have shown effectiveness in reducing blood pressure in hypertensive patients, similarly to first-line standard anti-hypertensive medications. Kyolic garlic has also shown promise in improving cardiovascular health by reducing arterial stiffness, elevated cholesterol levels and blood 'stickiness'. In addition, the prebiotic properties in garlic increase gut microbial richness and diversity. This article systematically reviews previously published trials investigating the effects of garlic on blood pressure, and provides an updated meta-analysis of hypertensive participants. In addition, we summarise the findings of recent clinical trials investigating the effects of Kyolic aged garlic extract on arterial stiffness, and gut microbiota in hypertensive subjects. We searched online electronic databases, including PubMed and Google Scholar for randomised controlled trials (RCTs) published between 1955 and December, 2018 examining the effects of garlic on high blood pressure. The meta-analysis of 12 trials and 553 hypertensive participants confirmed that garlic supplements lower systolic blood pressure (SBP) by an average of 8.3±1.9 mmHg and diastolic blood pressure (DBP, n=8 trials, n=374 subjects) by 5.5±1.9 mmHg, similarly to standard anti-hypertensive medications. This reduction in blood pressure was associated with a 16-40% reduction in the risk of suffering from cardiovascular events. Additionally, this review summarises new evidence for the vitamin B12 status playing an important role in the responsiveness of blood pressure to garlic. Furthermore, Kyolic aged garlic extract significantly lowered central blood pressure, pulse pressure, pulse wave velocity and arterial stiffness, and improved the gut microbiota, evidenced by higher microbial richness and diversity, with a marked increase in the numbers of
and
species found following 3 months of supplementation. Thus, Kyolic aged garlic extract is considered to be highly tolerable with a high safety profile either as a stand-alone or adjunctive anti-hypertensive treatment, with multiple benefits for cardiovascular health. Garlic supplements have shown effectiveness in reducing blood pressure in hypertensive patients, similarly to first-line standard anti-hypertensive medications. Kyolic garlic has also shown promise in improving cardiovascular health by reducing arterial stiffness, elevated cholesterol levels and blood 'stickiness'. In addition, the prebiotic properties in garlic increase gut microbial richness and diversity. This article systematically reviews previously published trials investigating the effects of garlic on blood pressure, and provides an updated meta-analysis of hypertensive participants. In addition, we summarise the findings of recent clinical trials investigating the effects of Kyolic aged garlic extract on arterial stiffness, and gut microbiota in hypertensive subjects. We searched online electronic databases, including PubMed and Google Scholar for randomised controlled trials (RCTs) published between 1955 and December, 2018 examining the effects of garlic on high blood pressure. The meta-analysis of 12 trials and 553 hypertensive participants confirmed that garlic supplements lower systolic blood pressure (SBP) by an average of 8.3 [+ or -] 1.9 mmHg and diastolic blood pressure (DBP, n=8 trials, n=374 subjects) by 5.5 [+ or -] 1.9 mmHg, similarly to standard anti-hypertensive medications. This reduction in blood pressure was associated with a 16-40% reduction in the risk of suffering from cardiovascular events. Additionally, this review summarises new evidence for the vitamin B12 status playing an important role in the responsiveness of blood pressure to garlic. Furthermore, Kyolic aged garlic extract significantly lowered central blood pressure, pulse pressure, pulse wave velocity and arterial stiffness, and improved the gut microbiota, evidenced by higher microbial richness and diversity, with a marked increase in the numbers of Lactobacillus and Clostridia species found following 3 months of supplementation. Thus, Kyolic aged garlic extract is considered to be highly tolerable with a high safety profile either as a stand-alone or adjunctive anti-hypertensive treatment, with multiple benefits for cardiovascular health. Garlic supplements have shown effectiveness in reducing blood pressure in hypertensive patients, similarly to first-line standard anti-hypertensive medications. Kyolic garlic has also shown promise in improving cardiovascular health by reducing arterial stiffness, elevated cholesterol levels and blood ‘stickiness’. In addition, the prebiotic properties in garlic increase gut microbial richness and diversity. This article systematically reviews previously published trials investigating the effects of garlic on blood pressure, and provides an updated meta-analysis of hypertensive participants. In addition, we summarise the findings of recent clinical trials investigating the effects of Kyolic aged garlic extract on arterial stiffness, and gut microbiota in hypertensive subjects. We searched online electronic databases, including PubMed and Google Scholar for randomised controlled trials (RCTs) published between 1955 and December, 2018 examining the effects of garlic on high blood pressure. The meta-analysis of 12 trials and 553 hypertensive participants confirmed that garlic supplements lower systolic blood pressure (SBP) by an average of 8.3±1.9 mmHg and diastolic blood pressure (DBP, n=8 trials, n=374 subjects) by 5.5±1.9 mmHg, similarly to standard anti-hypertensive medications. This reduction in blood pressure was associated with a 16–40% reduction in the risk of suffering from cardiovascular events. Additionally, this review summarises new evidence for the vitamin B12 status playing an important role in the responsiveness of blood pressure to garlic. Furthermore, Kyolic aged garlic extract significantly lowered central blood pressure, pulse pressure, pulse wave velocity and arterial stiffness, and improved the gut microbiota, evidenced by higher microbial richness and diversity, with a marked increase in the numbers of Lactobacillus and Clostridia species found following 3 months of supplementation. Thus, Kyolic aged garlic extract is considered to be highly tolerable with a high safety profile either as a stand-alone or adjunctive anti-hypertensive treatment, with multiple benefits for cardiovascular health. Garlic supplements have shown effectiveness in reducing blood pressure in hypertensive patients, similarly to first-line standard anti-hypertensive medications. Kyolic garlic has also shown promise in improving cardiovascular health by reducing arterial stiffness, elevated cholesterol levels and blood 'stickiness'. In addition, the prebiotic properties in garlic increase gut microbial richness and diversity. This article systematically reviews previously published trials investigating the effects of garlic on blood pressure, and provides an updated meta-analysis of hypertensive participants. In addition, we summarise the findings of recent clinical trials investigating the effects of Kyolic aged garlic extract on arterial stiffness, and gut microbiota in hypertensive subjects. We searched online electronic databases, including PubMed and Google Scholar for randomised controlled trials (RCTs) published between 1955 and December, 2018 examining the effects of garlic on high blood pressure. The meta-analysis of 12 trials and 553 hypertensive participants confirmed that garlic supplements lower systolic blood pressure (SBP) by an average of 8.3±1.9 mmHg and diastolic blood pressure (DBP, n=8 trials, n=374 subjects) by 5.5±1.9 mmHg, similarly to standard anti-hypertensive medications. This reduction in blood pressure was associated with a 16-40% reduction in the risk of suffering from cardiovascular events. Additionally, this review summarises new evidence for the vitamin B12 status playing an important role in the responsiveness of blood pressure to garlic. Furthermore, Kyolic aged garlic extract significantly lowered central blood pressure, pulse pressure, pulse wave velocity and arterial stiffness, and improved the gut microbiota, evidenced by higher microbial richness and diversity, with a marked increase in the numbers of Lactobacillus and Clostridia species found following 3 months of supplementation. Thus, Kyolic aged garlic extract is considered to be highly tolerable with a high safety profile either as a stand-alone or adjunctive anti-hypertensive treatment, with multiple benefits for cardiovascular health.Garlic supplements have shown effectiveness in reducing blood pressure in hypertensive patients, similarly to first-line standard anti-hypertensive medications. Kyolic garlic has also shown promise in improving cardiovascular health by reducing arterial stiffness, elevated cholesterol levels and blood 'stickiness'. In addition, the prebiotic properties in garlic increase gut microbial richness and diversity. This article systematically reviews previously published trials investigating the effects of garlic on blood pressure, and provides an updated meta-analysis of hypertensive participants. In addition, we summarise the findings of recent clinical trials investigating the effects of Kyolic aged garlic extract on arterial stiffness, and gut microbiota in hypertensive subjects. We searched online electronic databases, including PubMed and Google Scholar for randomised controlled trials (RCTs) published between 1955 and December, 2018 examining the effects of garlic on high blood pressure. The meta-analysis of 12 trials and 553 hypertensive participants confirmed that garlic supplements lower systolic blood pressure (SBP) by an average of 8.3±1.9 mmHg and diastolic blood pressure (DBP, n=8 trials, n=374 subjects) by 5.5±1.9 mmHg, similarly to standard anti-hypertensive medications. This reduction in blood pressure was associated with a 16-40% reduction in the risk of suffering from cardiovascular events. Additionally, this review summarises new evidence for the vitamin B12 status playing an important role in the responsiveness of blood pressure to garlic. Furthermore, Kyolic aged garlic extract significantly lowered central blood pressure, pulse pressure, pulse wave velocity and arterial stiffness, and improved the gut microbiota, evidenced by higher microbial richness and diversity, with a marked increase in the numbers of Lactobacillus and Clostridia species found following 3 months of supplementation. Thus, Kyolic aged garlic extract is considered to be highly tolerable with a high safety profile either as a stand-alone or adjunctive anti-hypertensive treatment, with multiple benefits for cardiovascular health. Garlic supplements have shown effectiveness in reducing blood pressure in hypertensive patients, similarly to first-line standard anti-hypertensive medications. Kyolic garlic has also shown promise in improving cardiovascular health by reducing arterial stiffness, elevated cholesterol levels and blood 'stickiness'. In addition, the prebiotic properties in garlic increase gut microbial richness and diversity. This article systematically reviews previously published trials investigating the effects of garlic on blood pressure, and provides an updated meta-analysis of hypertensive participants. In addition, we summarise the findings of recent clinical trials investigating the effects of Kyolic aged garlic extract on arterial stiffness, and gut microbiota in hypertensive subjects. We searched online electronic databases, including PubMed and Google Scholar for randomised controlled trials (RCTs) published between 1955 and December, 2018 examining the effects of garlic on high blood pressure. The meta-analysis of 12 trials and 553 hypertensive participants confirmed that garlic supplements lower systolic blood pressure (SBP) by an average of 8.3 [+ or -] 1.9 mmHg and diastolic blood pressure (DBP, n=8 trials, n=374 subjects) by 5.5 [+ or -] 1.9 mmHg, similarly to standard anti-hypertensive medications. This reduction in blood pressure was associated with a 16-40% reduction in the risk of suffering from cardiovascular events. Additionally, this review summarises new evidence for the vitamin B12 status playing an important role in the responsiveness of blood pressure to garlic. Furthermore, Kyolic aged garlic extract significantly lowered central blood pressure, pulse pressure, pulse wave velocity and arterial stiffness, and improved the gut microbiota, evidenced by higher microbial richness and diversity, with a marked increase in the numbers of Lactobacillus and Clostridia species found following 3 months of supplementation. Thus, Kyolic aged garlic extract is considered to be highly tolerable with a high safety profile either as a stand-alone or adjunctive anti-hypertensive treatment, with multiple benefits for cardiovascular health. Key words: aged garlic extract, blood pressure, hypertension, meta-analysis, pulse wave velocity, arterial stiffness, gut microbiome Garlic supplements have shown effectiveness in reducing blood pressure in hypertensive patients, similarly to first-line standard anti-hypertensive medications. Kyolic garlic has also shown promise in improving cardiovascular health by reducing arterial stiffness, elevated cholesterol levels and blood ‘stickiness’. In addition, the prebiotic properties in garlic increase gut microbial richness and diversity. This article systematically reviews previously published trials investigating the effects of garlic on blood pressure, and provides an updated meta-analysis of hypertensive participants. In addition, we summarise the findings of recent clinical trials investigating the effects of Kyolic aged garlic extract on arterial stiffness, and gut microbiota in hypertensive subjects. We searched online electronic databases, including PubMed and Google Scholar for randomised controlled trials (RCTs) published between 1955 and December, 2018 examining the effects of garlic on high blood pressure. The meta-analysis of 12 trials and 553 hypertensive participants confirmed that garlic supplements lower systolic blood pressure (SBP) by an average of 8.3±1.9 mmHg and diastolic blood pressure (DBP, n=8 trials, n=374 subjects) by 5.5±1.9 mmHg, similarly to standard anti-hypertensive medications. This reduction in blood pressure was associated with a 16–40% reduction in the risk of suffering from cardiovascular events. Additionally, this review summarises new evidence for the vitamin B12 status playing an important role in the responsiveness of blood pressure to garlic. Furthermore, Kyolic aged garlic extract significantly lowered central blood pressure, pulse pressure, pulse wave velocity and arterial stiffness, and improved the gut microbiota, evidenced by higher microbial richness and diversity, with a marked increase in the numbers of Lactobacillus and Clostridia species found following 3 months of supplementation. Thus, Kyolic aged garlic extract is considered to be highly tolerable with a high safety profile either as a stand-alone or adjunctive anti-hypertensive treatment, with multiple benefits for cardiovascular health. |
| Audience | Academic |
| Author | Ried, Karin |
| AuthorAffiliation | 2 Department of General Practice, The University of Adelaide, South Australia 5000, Australia 3 Torrens University, Melbourne, Victoria 3000, Australia 1 National Institute of Integrative Medicine (NIIM), Hawthorn, Melbourne, Victoria 3122, Australia |
| AuthorAffiliation_xml | – name: 3 Torrens University, Melbourne, Victoria 3000, Australia – name: 2 Department of General Practice, The University of Adelaide, South Australia 5000, Australia – name: 1 National Institute of Integrative Medicine (NIIM), Hawthorn, Melbourne, Victoria 3122, Australia |
| Author_xml | – sequence: 1 givenname: Karin surname: Ried fullname: Ried, Karin organization: National Institute of Integrative Medicine (NIIM), Hawthorn, Melbourne, Victoria 3122, Australia |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/32010325$$D View this record in MEDLINE/PubMed |
| BookMark | eNptUk1v1DAQjVAR_aBHrsgSFw7NYieO43CotKqgIFXiAmfLccZbrxw72M5We-Sf49At0Kr2wZbnvTd-M3NaHDnvoCjeELyqeVd9gDSuKky6Fa9b-qI4IW1XlQST5uhwxx0nx8V5jFucV8MI582r4rjOJFxXzUnx61oGaxSy_g5CRL31fkBTgBjnAMg4dLufICRw0ewAxbnfgkrxAplxCn4HEckcDEZaFJPR2mUikm5Amzmh0ajge-OT_IjWKMDOwN2f4AhJltJJu48mvi5eamkjnB_Os-LH50_fr76UN9-uv16tb0pFSZVKqhnFjQTadrwBaAbdyo72A-9xS1lPKqgHqWraAae640zrbHZQpNXdwHrd1mfF5b3uNPcjDApcCtKKKZhRhr3w0ojHEWduxcbvBOsYy9XKAu8PAsH_nCEmMZqowFrpwM9RVHWDcxswXnK9ewLd-jlkwwuKErr0rP6H2kgLwjjtc161iIo1I6zlvGU0o1bPoPIeIBc4z4M2-f0R4e3_Rv86fGh6BtT3gNyeGANooUySyfjFt7GCYLFMl8jTJZafimW6Mqt8wnoQfh7_G5OH0q0 |
| CitedBy_id | crossref_primary_10_2174_2772432819666230504093227 crossref_primary_10_1007_s00394_023_03110_2 crossref_primary_10_1186_s12944_023_01809_z crossref_primary_10_3389_fvets_2023_1277272 crossref_primary_10_1007_s40292_022_00507_8 crossref_primary_10_1155_2022_6960211 crossref_primary_10_1016_j_mvr_2023_104601 crossref_primary_10_1155_2021_6636875 crossref_primary_10_26599_JFB_2024_95027386 crossref_primary_10_3892_br_2024_1733 crossref_primary_10_1007_s42535_025_01184_3 crossref_primary_10_3892_etm_2024_12791 crossref_primary_10_3389_fphar_2024_1321523 crossref_primary_10_1016_j_prmcm_2023_100273 crossref_primary_10_20960_nh_04471 |
| Cites_doi | 10.1073/pnas.1412008111 10.1007/s00281-012-0337-5 10.1161/HYPERTENSIONAHA.115.05315 10.3892/etm.2012.819 10.1152/physrev.00045.2009 10.1097/00004872-199404000-00017 10.1016/S0140-6736(02)11911-8 10.1136/gutjnl-2015-309990 10.1186/1471-2261-8-13 10.1016/j.nut.2012.03.016 10.1093/jn/136.3.793S 10.2147/IBPC.S51434 10.1093/eurheartj/ehl254 10.1097/MIB.0000000000000345 10.1002/mnfr.200700058 10.1016/S0140-6736(15)01225-8 10.1093/jn/136.3.716S 10.1080/080370599438266 10.1093/jn/131.3.955S 10.3945/jn.114.202192 10.1186/1471-2261-12-48 10.1111/nure.12012 10.1073/pnas.0705710104 10.1093/ajh/hpu165 10.5812/ircmj.23871 10.5551/jat.E550 10.1161/HYPERTENSIONAHA.114.03469 10.1016/j.phymed.2012.02.018 10.1152/ajpheart.00598.2010 10.1161/01.HYP.15.4.339 10.3390/nu5041417 10.1016/j.aimed.2015.11.002 10.3389/fnut.2018.00122 10.1038/hr.2009.36 10.1016/j.maturitas.2010.06.001 10.2147/IBPC.S93335 10.1097/MBP.0000000000000066 10.1111/jgh.12306 10.1345/aph.1L319 10.1038/ejcn.2012.178 |
| ContentType | Journal Article |
| Copyright | Copyright: © Ried et al. COPYRIGHT 2020 Spandidos Publications Copyright Spandidos Publications UK Ltd. 2020 Copyright: © Ried et al. 2020 |
| Copyright_xml | – notice: Copyright: © Ried et al. – notice: COPYRIGHT 2020 Spandidos Publications – notice: Copyright Spandidos Publications UK Ltd. 2020 – notice: Copyright: © Ried et al. 2020 |
| DBID | AAYXX CITATION NPM 3V. 7RV 7X7 7XB 8FI 8FJ 8FK ABUWG AFKRA AN0 BENPR CCPQU FYUFA GHDGH K9. KB0 M0S NAPCQ PHGZM PHGZT PKEHL PPXIY PQEST PQQKQ PQUKI PRINS 7X8 5PM |
| DOI | 10.3892/etm.2019.8374 |
| DatabaseName | CrossRef PubMed ProQuest Central (Corporate) ProQuest Nursing and Allied Health Journals - PSU access expires 11/30/25. Health & Medical Collection ProQuest Central (purchase pre-March 2016) ProQuest Hospital Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) ProQuest Central (Alumni) ProQuest Central UK/Ireland British Nursing Index ProQuest Central ProQuest One Community College Health Research Premium Collection Health Research Premium Collection (Alumni) ProQuest Health & Medical Complete (Alumni) Nursing & Allied Health Database (Alumni Edition) Health & Medical Collection (Alumni) Nursing & Allied Health Premium ProQuest Central Premium ProQuest One Academic ProQuest One Academic Middle East (New) ProQuest One Health & Nursing ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Academic ProQuest One Academic UKI Edition ProQuest Central China MEDLINE - Academic PubMed Central (Full Participant titles) |
| DatabaseTitle | CrossRef PubMed ProQuest One Academic Middle East (New) ProQuest One Academic Eastern Edition ProQuest Health & Medical Complete (Alumni) British Nursing Index with Full Text ProQuest Central (Alumni Edition) ProQuest One Community College ProQuest One Health & Nursing ProQuest Nursing & Allied Health Source ProQuest Hospital Collection Health Research Premium Collection (Alumni) ProQuest Central China ProQuest Hospital Collection (Alumni) ProQuest Central Nursing & Allied Health Premium ProQuest Health & Medical Complete Health Research Premium Collection ProQuest One Academic UKI Edition Health and Medicine Complete (Alumni Edition) ProQuest Nursing & Allied Health Source (Alumni) ProQuest Central (New) ProQuest One Academic ProQuest One Academic (New) ProQuest Central (Alumni) MEDLINE - Academic |
| DatabaseTitleList | PubMed ProQuest One Academic Middle East (New) MEDLINE - Academic |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: BENPR name: ProQuest Central url: https://www.proquest.com/central sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Pharmacy, Therapeutics, & Pharmacology |
| EISSN | 1792-1015 |
| EndPage | 1478 |
| ExternalDocumentID | PMC6966103 A616788764 32010325 10_3892_etm_2019_8374 |
| Genre | Journal Article |
| GeographicLocations | Australia |
| GeographicLocations_xml | – name: Australia |
| GroupedDBID | --- 0R~ 53G 7RV 7X7 8FI 8FJ AAKDD AAYXX ABDBF ABJNI ABUWG ACGFS ACUHS ADBBV AENEX AFKRA AHMBA ALIPV ALMA_UNASSIGNED_HOLDINGS AN0 BENPR BKEYQ BNQBC BPHCQ BVXVI C45 CCPQU CITATION EBD EBS EJD ESX F5P FYUFA H13 HMCUK HUR HZ~ IAO IHR IPNFZ ITC NAPCQ O9- OVD PHGZM PHGZT PQQKQ PROAC RIG RPM TEORI UKHRP 3V. NPM OK1 PMFND 7XB 8FK K9. PKEHL PPXIY PQEST PQUKI PRINS 7X8 5PM |
| ID | FETCH-LOGICAL-c412t-4f6405ae47985ee5df7a94bd8b0746b12e3dac349e84f986ff618dc17f9d6bf73 |
| IEDL.DBID | 7X7 |
| ISSN | 1792-0981 |
| IngestDate | Thu Aug 21 18:28:15 EDT 2025 Fri Jul 11 03:50:44 EDT 2025 Sat Aug 23 14:01:59 EDT 2025 Tue Jun 17 20:58:44 EDT 2025 Tue Jun 10 20:36:23 EDT 2025 Thu Jan 02 22:59:34 EST 2025 Tue Jul 01 02:59:54 EDT 2025 Thu Apr 24 23:09:20 EDT 2025 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | false |
| IsScholarly | true |
| Issue | 2 |
| Keywords | arterial stiffness blood pressure gut microbiome meta-analysis pulse wave velocity hypertension aged garlic extract |
| Language | English |
| License | Copyright: © Ried et al. This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c412t-4f6405ae47985ee5df7a94bd8b0746b12e3dac349e84f986ff618dc17f9d6bf73 |
| Notes | ObjectType-Article-2 SourceType-Scholarly Journals-1 content type line 14 ObjectType-Feature-3 ObjectType-Evidence Based Healthcare-1 ObjectType-Article-1 ObjectType-Feature-2 content type line 23 |
| OpenAccessLink | https://pubmed.ncbi.nlm.nih.gov/PMC6966103 |
| PMID | 32010325 |
| PQID | 2341420193 |
| PQPubID | 2044959 |
| PageCount | 7 |
| ParticipantIDs | pubmedcentral_primary_oai_pubmedcentral_nih_gov_6966103 proquest_miscellaneous_2350374007 proquest_journals_2341420193 gale_infotracmisc_A616788764 gale_infotracacademiconefile_A616788764 pubmed_primary_32010325 crossref_citationtrail_10_3892_etm_2019_8374 crossref_primary_10_3892_etm_2019_8374 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | 2020-02-01 |
| PublicationDateYYYYMMDD | 2020-02-01 |
| PublicationDate_xml | – month: 02 year: 2020 text: 2020-02-01 day: 01 |
| PublicationDecade | 2020 |
| PublicationPlace | Greece |
| PublicationPlace_xml | – name: Greece – name: Athens |
| PublicationTitle | Experimental and therapeutic medicine |
| PublicationTitleAlternate | Exp Ther Med |
| PublicationYear | 2020 |
| Publisher | Spandidos Publications Spandidos Publications UK Ltd D.A. Spandidos |
| Publisher_xml | – name: Spandidos Publications – name: Spandidos Publications UK Ltd – name: D.A. Spandidos |
| References | Ried (key20200713005728_b4-etm-0-0-8374) 2016; 146 Olsen (key20200713005728_b10-etm-0-0-8374) 1999; 8 Khalesi (key20200713005728_b25-etm-0-0-8374) 2014; 64 Ng (key20200713005728_b24-etm-0-0-8374) 2013; 28 Larijani (key20200713005728_b12-etm-0-0-8374) 2013; 29 key20200713005728_b38-etm-0-0-8374 Ried (key20200713005728_b1-etm-0-0-8374) 2008; 8 Marchesi (key20200713005728_b19-etm-0-0-8374) 2016; 65 Silagy (key20200713005728_b26-etm-0-0-8374) 1994; 12 Nakasone (key20200713005728_b35-etm-0-0-8374) 2013; 5 Sekirov (key20200713005728_b20-etm-0-0-8374) 2010; 90 Laurent (key20200713005728_b11-etm-0-0-8374) 2006; 27 Sobenin (key20200713005728_b34-etm-0-0-8374) 2009; 32 Rohner (key20200713005728_b3-etm-0-0-8374) 2015; 28 Yang (key20200713005728_b18-etm-0-0-8374) 2015; 65 Nunan (key20200713005728_b13-etm-0-0-8374) 2012; 12 Travica (key20200713005728_b17-etm-0-0-8374) 2015; 2 Santos (key20200713005728_b32-etm-0-0-8374) 1993; 4 Ried (key20200713005728_b16-etm-0-0-8374) 2014; 7 Ried (key20200713005728_b8-etm-0-0-8374) 2018; 5 Macan (key20200713005728_b46-etm-0-0-8374) 2006; 136 Beard (key20200713005728_b43-etm-0-0-8374) 2011; 300 (key20200713005728_b9-etm-0-0-8374) 2012; 61 Kandziora (key20200713005728_b28-etm-0-0-8374) 1988; 35 Reinhart (key20200713005728_b2-etm-0-0-8374) 2008; 42 Motta (key20200713005728_b23-etm-0-0-8374) 2015; 21 Slavin (key20200713005728_b47-etm-0-0-8374) 2013; 5 O'Rourke (key20200713005728_b15-etm-0-0-8374) 1990; 15 Mahdavi-Roshan (key20200713005728_b36-etm-0-0-8374) 2016; 18 Holzgartner (key20200713005728_b31-etm-0-0-8374) 1992; 42 Lewington (key20200713005728_b41-etm-0-0-8374) 2002; 360 Nunan (key20200713005728_b14-etm-0-0-8374) 2014; 19 Benavides (key20200713005728_b21-etm-0-0-8374) 2007; 104 Vorberg (key20200713005728_b30-etm-0-0-8374) 1990; 69 Stefka (key20200713005728_b48-etm-0-0-8374) 2014; 111 Amagase (key20200713005728_b40-etm-0-0-8374) 2001; 131 Ried (key20200713005728_b44-etm-0-0-8374) 2013; 71 Filocamo (key20200713005728_b22-etm-0-0-8374) 2012; 19 Amagase (key20200713005728_b39-etm-0-0-8374) 2006; 136 Ried (key20200713005728_b7-etm-0-0-8374) 2016; 9 Rahman (key20200713005728_b45-etm-0-0-8374) 2007; 51 Ried (key20200713005728_b5-etm-0-0-8374) 2010; 67 Ettehad (key20200713005728_b42-etm-0-0-8374) 2016; 387 Manager (key20200713005728_b27-etm-0-0-8374) 2014 Zeb (key20200713005728_b37-etm-0-0-8374) 2018; 31 Auer (key20200713005728_b29-etm-0-0-8374) 1990; 69 Feehley (key20200713005728_b49-etm-0-0-8374) 2012; 34 Sobenin (key20200713005728_b33-etm-0-0-8374) 2008; 15 Ried (key20200713005728_b6-etm-0-0-8374) 2013; 67 |
| References_xml | – volume: 111 start-page: 13145 year: 2014 ident: key20200713005728_b48-etm-0-0-8374 article-title: Commensal bacteria protect against food allergen sensitization publication-title: Proc Natl Acad Sci USA doi: 10.1073/pnas.1412008111 – volume: 34 start-page: 671 year: 2012 ident: key20200713005728_b49-etm-0-0-8374 article-title: Microbial regulation of allergic responses to food publication-title: Semin Immunopathol doi: 10.1007/s00281-012-0337-5 – volume: 65 start-page: 1331 year: 2015 ident: key20200713005728_b18-etm-0-0-8374 article-title: Gut dysbiosis is linked to hypertension publication-title: Hypertension doi: 10.1161/HYPERTENSIONAHA.115.05315 – volume: 5 start-page: 399 year: 2013 ident: key20200713005728_b35-etm-0-0-8374 article-title: Effect of a traditional Japanese garlic preparation on blood pressure in prehypertensive and mildly hypertensive adults publication-title: Exp Ther Med doi: 10.3892/etm.2012.819 – volume: 90 start-page: 859 year: 2010 ident: key20200713005728_b20-etm-0-0-8374 article-title: Gut microbiota in health and disease publication-title: Physiol Rev doi: 10.1152/physrev.00045.2009 – volume: 12 start-page: 463 year: 1994 ident: key20200713005728_b26-etm-0-0-8374 article-title: A meta-analysis of the effect of garlic on blood pressure publication-title: J Hypertens doi: 10.1097/00004872-199404000-00017 – year: 2014 ident: key20200713005728_b27-etm-0-0-8374 article-title: (RevMan) [Computer program]. Version 5.3 Copenhagen: The Nordic Cochrane Centre, The Cochrane Collaboration – volume: 42 start-page: 1473 year: 1992 ident: key20200713005728_b31-etm-0-0-8374 article-title: Comparison of the efficacy and tolerance of a garlic preparation vs. bezafibrate publication-title: Arzneimittelforschung – volume: 360 start-page: 1903 year: 2002 ident: key20200713005728_b41-etm-0-0-8374 article-title: Age-specific relevance of usual blood pressure to vascular mortality: A meta-analysis of individual data for one million adults in 61 prospective studies publication-title: Lancet doi: 10.1016/S0140-6736(02)11911-8 – volume: 69 start-page: 3 year: 1990 ident: key20200713005728_b29-etm-0-0-8374 article-title: Hypertension and hyperlipidaemia: Garlic helps in mild cases publication-title: Br J Clin Pract Suppl – volume: 65 start-page: 330 year: 2016 ident: key20200713005728_b19-etm-0-0-8374 article-title: The gut microbiota and host health: A new clinical frontier publication-title: Gut doi: 10.1136/gutjnl-2015-309990 – volume: 8 start-page: 13 year: 2008 ident: key20200713005728_b1-etm-0-0-8374 article-title: Effect of garlic on blood pressure: A systematic review and meta-analysis publication-title: BMC Cardiovasc Disord doi: 10.1186/1471-2261-8-13 – volume: 29 start-page: 71 year: 2013 ident: key20200713005728_b12-etm-0-0-8374 article-title: Beneficial effects of aged garlic extract and coenzyme Q10 on vascular elasticity and endothelial function: The FAITH randomized clinical trial publication-title: Nutrition doi: 10.1016/j.nut.2012.03.016 – volume: 136 start-page: 793S year: 2006 ident: key20200713005728_b46-etm-0-0-8374 article-title: Aged garlic extract may be safe for patients on warfarin therapy publication-title: J Nutr doi: 10.1093/jn/136.3.793S – volume: 7 start-page: 71 year: 2014 ident: key20200713005728_b16-etm-0-0-8374 article-title: Potential of garlic (Allium sativum) in lowering high blood pressure: Mechanisms of action and clinical relevance publication-title: Integr Blood Press Control doi: 10.2147/IBPC.S51434 – volume: 27 start-page: 2588 year: 2006 ident: key20200713005728_b11-etm-0-0-8374 article-title: Expert consensus document on arterial stiffness: Methodological issues and clinical applications publication-title: Eur Heart J doi: 10.1093/eurheartj/ehl254 – volume: 21 start-page: 1006 year: 2015 ident: key20200713005728_b23-etm-0-0-8374 article-title: Hydrogen sulfide protects from colitis and restores intestinal microbiota biofilm and mucus production publication-title: Inflamm Bowel Dis doi: 10.1097/MIB.0000000000000345 – volume: 51 start-page: 1335 year: 2007 ident: key20200713005728_b45-etm-0-0-8374 article-title: Effects of garlic on platelet biochemistry and physiology publication-title: Mol Nutr Food Res doi: 10.1002/mnfr.200700058 – volume: 387 start-page: 957 year: 2016 ident: key20200713005728_b42-etm-0-0-8374 article-title: Blood pressure lowering for prevention of cardiovascular disease and death: A systematic review and meta-analysis publication-title: Lancet doi: 10.1016/S0140-6736(15)01225-8 – volume: 136 start-page: 716S year: 2006 ident: key20200713005728_b39-etm-0-0-8374 article-title: Clarifying the real bioactive constituents of garlic publication-title: J Nutr doi: 10.1093/jn/136.3.716S – volume: 8 start-page: 94 year: 1999 ident: key20200713005728_b10-etm-0-0-8374 article-title: Adverse drug reactions in current antihypertensive therapy: A general practice survey of 2586 patients in Norway publication-title: Blood Pressure doi: 10.1080/080370599438266 – volume: 131 start-page: 955S year: 2001 ident: key20200713005728_b40-etm-0-0-8374 article-title: Intake of garlic and its bioactive components publication-title: J Nutr doi: 10.1093/jn/131.3.955S – volume: 146 start-page: 3895 year: 2016 ident: key20200713005728_b4-etm-0-0-8374 article-title: Effect of garlic on blood pressure, serum cholesterol and immunity: Updated meta-analyses and review publication-title: J Nutr doi: 10.3945/jn.114.202192 – volume: 12 start-page: 48 year: 2012 ident: key20200713005728_b13-etm-0-0-8374 article-title: Assessment of central haemomodynamics from a brachial cuff in a community setting publication-title: BMC Cardiovasc Disord doi: 10.1186/1471-2261-12-48 – volume: 71 start-page: 282 year: 2013 ident: key20200713005728_b44-etm-0-0-8374 article-title: Effect of garlic on serum lipids: An updated meta-analysis publication-title: Nutr Rev doi: 10.1111/nure.12012 – volume: 35 start-page: 3 year: 1988 ident: key20200713005728_b28-etm-0-0-8374 article-title: Blutdruck und Lipidsenkende Wirkung eines Knoblauch-Präparates in Kombination mit einem Diuretikum. Blood pressure and lipid reducing effect of a garlic supplement in combination with a diuretic publication-title: Arztl Forsch – volume: 104 start-page: 17977 year: 2007 ident: key20200713005728_b21-etm-0-0-8374 article-title: Hydrogen sulfide mediates the vasoactivity of garlic publication-title: Proc Natl Acad Sci USA doi: 10.1073/pnas.0705710104 – volume: 4 start-page: 37 year: 1993 ident: key20200713005728_b32-etm-0-0-8374 article-title: Effect of garlic powder tablets on blood lipids and blood pressure: A six-month placebo-controlled, double-blind study publication-title: Br J Clin Res – volume: 28 start-page: 414 year: 2015 ident: key20200713005728_b3-etm-0-0-8374 article-title: A systematic review and meta-analysis on the effects of garlic preparations on blood pressure in individuals with hypertension publication-title: Am J Hypertens doi: 10.1093/ajh/hpu165 – volume: 18 start-page: e23871 year: 2016 ident: key20200713005728_b36-etm-0-0-8374 article-title: Does garlic supplementation control blood pressure in patients with severe coronary artery disease? A clinical trial study publication-title: Iran Red Crescent Med J doi: 10.5812/ircmj.23871 – volume: 15 start-page: 334 year: 2008 ident: key20200713005728_b33-etm-0-0-8374 article-title: Lipid-lowering effects of time-released garlic powder tablets in double-blinded placebo-controlled randomized study publication-title: J Atheroscler Thromb doi: 10.5551/jat.E550 – volume: 64 start-page: 897 year: 2014 ident: key20200713005728_b25-etm-0-0-8374 article-title: Effect of probiotics on blood pressure: A systematic review and meta-analysis of randomized, controlled trials publication-title: Hypertension doi: 10.1161/HYPERTENSIONAHA.114.03469 – volume: 19 start-page: 707 year: 2012 ident: key20200713005728_b22-etm-0-0-8374 article-title: Effect of garlic powder on the growth of commensal bacteria from the gastrointestinal tract publication-title: Phytomedicine doi: 10.1016/j.phymed.2012.02.018 – volume: 300 start-page: H13 year: 2011 ident: key20200713005728_b43-etm-0-0-8374 article-title: Vascular complications of cystathionine β-synthase deficiency: Future directions for homocysteine-to-hydrogen sulfide research publication-title: Am J Physiol Heart Circ Physiol doi: 10.1152/ajpheart.00598.2010 – volume: 15 start-page: 339 year: 1990 ident: key20200713005728_b15-etm-0-0-8374 article-title: Arterial stiffness, systolic blood pressure, and logical treatment of arterial hypertension publication-title: Hypertension doi: 10.1161/01.HYP.15.4.339 – volume: 5 start-page: 1417 year: 2013 ident: key20200713005728_b47-etm-0-0-8374 article-title: Fiber and prebiotics: Mechanisms and health benefits publication-title: Nutrients doi: 10.3390/nu5041417 – volume: 69 start-page: 7 year: 1990 ident: key20200713005728_b30-etm-0-0-8374 article-title: Therapy with garlic: Results of a placebo-controlled, double-blind study publication-title: Br J Clin Pract Suppl – volume: 2 start-page: 135 year: 2015 ident: key20200713005728_b17-etm-0-0-8374 article-title: Integrative Health Check reveals suboptimal levels in a number of vital biomarkers publication-title: Adv Integr Med doi: 10.1016/j.aimed.2015.11.002 – volume: 5 start-page: 122 year: 2018 ident: key20200713005728_b8-etm-0-0-8374 article-title: The effect of kyolic aged garlic extract on gut microbiota, inflammation, and cardiovascular markers in hypertensives: The GarGIC Trial publication-title: Front Nutr doi: 10.3389/fnut.2018.00122 – volume: 32 start-page: 433 year: 2009 ident: key20200713005728_b34-etm-0-0-8374 article-title: Time-released garlic powder tablets lower systolic and diastolic blood pressure in men with mild and moderate arterial hypertension publication-title: Hypertens Res doi: 10.1038/hr.2009.36 – volume: 67 start-page: 144 year: 2010 ident: key20200713005728_b5-etm-0-0-8374 article-title: Aged garlic extract lowers blood pressure in patients with treated but uncontrolled hypertension: A randomised controlled trial publication-title: Maturitas doi: 10.1016/j.maturitas.2010.06.001 – ident: key20200713005728_b38-etm-0-0-8374 article-title: Kyolic Aged Garlic Extract Reserve formula – volume: 31 start-page: 1935 year: 2018 ident: key20200713005728_b37-etm-0-0-8374 article-title: Supplementation of garlic and coriander seed powder: Impact on body mass index, lipid profile and blood pressure of hyperlipidemic patients publication-title: Pak J Pharm Sci – volume: 9 start-page: 9 year: 2016 ident: key20200713005728_b7-etm-0-0-8374 article-title: The effect of aged garlic extract on blood pressure and other cardiovascular risk factors in uncontrolled hypertensives: The AGE at Heart trial publication-title: Integr Blood Press Control doi: 10.2147/IBPC.S93335 – volume: 61 start-page: 703 year: 2012 ident: key20200713005728_b9-etm-0-0-8374 article-title: Centers for Disease Control and Prevention (CDC): Vital signs: Awareness and treatment of uncontrolled hypertension among adults - United States, 2003–2010 publication-title: MMWR Morb Mortal Wkly Rep – volume: 19 start-page: 315 year: 2014 ident: key20200713005728_b14-etm-0-0-8374 article-title: Performance of pulse wave velocity measured using a brachial cuff in a community setting publication-title: Blood Press Monit doi: 10.1097/MBP.0000000000000066 – volume: 28 start-page: 1624 year: 2013 ident: key20200713005728_b24-etm-0-0-8374 article-title: Effect of probiotic bacteria on the intestinal microbiota in irritable bowel syndrome publication-title: J Gastroenterol Hepatol doi: 10.1111/jgh.12306 – volume: 42 start-page: 1766 year: 2008 ident: key20200713005728_b2-etm-0-0-8374 article-title: Effects of garlic on blood pressure in patients with and without systolic hypertension: A meta-analysis publication-title: Ann Pharmacother doi: 10.1345/aph.1L319 – volume: 67 start-page: 64 year: 2013 ident: key20200713005728_b6-etm-0-0-8374 article-title: Aged garlic extract reduces blood pressure in hypertensives: A dose-response trial publication-title: Eur J Clin Nutr doi: 10.1038/ejcn.2012.178 |
| SSID | ssj0000561885 |
| Score | 2.4086726 |
| Snippet | Garlic supplements have shown effectiveness in reducing blood pressure in hypertensive patients, similarly to first-line standard anti-hypertensive... |
| SourceID | pubmedcentral proquest gale pubmed crossref |
| SourceType | Open Access Repository Aggregation Database Index Database Enrichment Source |
| StartPage | 1472 |
| SubjectTerms | Analysis Antihypertensive agents Bias Blood pressure Cardiovascular agents Cardiovascular disease Cholesterol Clinical trials Digestive system Garlic Gut microbiota Health Hypertension Medical research Meta-analysis Microbiota Microbiota (Symbiotic organisms) Online searching Probiotics Retirement benefits Studies Suffering Wave propagation |
| Title | Garlic lowers blood pressure in hypertensive subjects, improves arterial stiffness and gut microbiota: A review and meta-analysis |
| URI | https://www.ncbi.nlm.nih.gov/pubmed/32010325 https://www.proquest.com/docview/2341420193 https://www.proquest.com/docview/2350374007 https://pubmed.ncbi.nlm.nih.gov/PMC6966103 |
| Volume | 19 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1Na9wwEBVtcuml9Ltu0qBC2V7WxJZly-6lbEvSUGhYSgJ7M5IsJQsbb7K2Dzn2n3dG1nrjQnvW2AjPaGY0fvOGkI_SgOXaSITSsCzkVZSGMtUcbimWMyVtoVzf2s_z7OyS_1ikC19wazyscusTnaOu1hpr5McM3C2HaFUkX27vQpwahX9X_QiNx2QfqcsQ0iUWYqixYHacu6mcYHYsjIo87mk2IUqzY9NiJ3oMtpIIPgpLfzvnB9FpjJx8EIpOn5GnPoeks17pz8kjU78gk3lPQn0_pRe7nqpmSid0vqOnvn9Jfn-Xm9VS05Wbj0Ydcp06OGy3MXRZ02u4mm48sJ02ncJKDbxn6coPpqEOBQpmS8E7WIuuksq6olddS2-WPa9TKz_TGe3bYtzijWllKD0ByityeXpy8e0s9IMYQs1j1obcZpDXScNFkafGpJUVsuCqyhVOK1ExM0kldcILk3Nb5Jm18N0rHQtbVJmyInlN9up1bd4SmnAdca0k01JwpZWyWQpWkuvKFiaKbECmWz2U2rOU47CMVQm3FVRbCWorUW0lqi0gk0H8tqfn-JfgJ1RqiccW3qel7z6AXSEBVjnL4gyBlRlIHo4k4bjp8fLWLEp_3JtyZ5wB-TAs45MIYavNukOZFLl-ICcLyJveioYtJ4hJSFgaEDGyr0EAScDHK_Xy2pGBZ3BfhWff_X9bB-QJw0KBg5sfkr1205n3kE216sgdmSOy__XkfP7rD_FhJBc |
| linkProvider | ProQuest |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV3db9MwELdG9wAviG-6DTASlJdGSxzHSZAQKrDRsa2qUCftLdiOzSp16WhToT7yD_E3cuek7YIEb3v2xbJ035e73xHyShqQXOvHnjRMeDz3I09GmkOWYjlT0qbKza2dDkT_jH85j863yO_VLAy2Va5sojPU-VRjjXyfgbnl4K3S8P3VDw-3RuHf1dUKjUosjs3yJ6Rs83dHn4C_rxk7PBh97Hv1VgFP84CVHrcCghRpeJwmkTFRbmOZcpUnCldvqICZMJc65KlJuE0TYa0IklwHsU1zoWwcwr23yDYPIZVpke0PB4Ph13VVB-PxxO0BBUFnnp8mQQXsCXEB2zclzr4HIJ1hzBuO8G93cM0fNns1rzm_w3vkbh210l4lZvfJlikekM6wgr1eduloM8U179IOHW4AsZcPya_PcjYZazpxG9mo65WnrgF3MTN0XNALSIZndSs9nS8U1obgnrEreJg5dX2noCgU7JG1aJypLHL6fVHSy3GFJFXKt7RHq0Ecd3hpSunJGnLlETm7ESY9Jq1iWpinhIZc-1wrybSMudJKWRGBXCY6t6nxfdsm3RUfMl3jouN6jkkG-RGyLQO2Zci2DNnWJp01-VUFCPIvwjfI1AwNBdynZT3vAK9CyK2sJwKBrZwCKPcalKDgunm8EousNjDzbKMObfJyfYxfYtNcYaYLpIkQXQiiwDZ5UknR-skhdkGELGqTuCFfawKEHW-eFOMLBz8uIEOGb3f-_6wX5HZ_dHqSnRwNjnfJHYZlCtfsvkda5WxhnkEsV6rntQJR8u2mdfYPkXJhlg |
| linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV3Nb9MwFLfGkBAXxDeFAUaCcmnUxHHsBAmhilE2BlMPm9RbZjs2q9Slo02FeuTf4q_jPSdtFyS47ewXy9L7tPN7v0fIa2XBcl0oA2WZCHgRJoFKDIdbiuNMK5dp37f27VgcnPIv42S8Q36ve2EQVrmOiT5QFzODb-R9BuGWQ7bK4r5rYBGj_eGHyx8BTpDCP63rcRq1iRzZ1U-4vi3eH-6Drt8wNvx08vEgaCYMBIZHrAq4E1CwKMtllibWJoWTKuO6SDWO4dARs3GhTMwzm3KXpcI5EaWFiaTLCqGdjGHfG-SmjJMIfUyO5eZ9Byvz1E8EBZNnQZilUU3xCRUC69sKu-AjsNNY8lZK_DsxXMmMbdTmlTQ4vEvuNPUrHdQGd4_s2PI-6Y5qAuxVj55s-7kWPdqloy019uoB-fVZzacTQ6d-Nhv1qHnqobjLuaWTkp7DtXjegOrpYqnxlQj2mfinD7ugHoEKLkMhMjmHYZqqsqDflxW9mNScUpV6Rwe0bsnxixe2UoFqyFcektNrUdEjslvOSvuE0JibkButmFGSa6O1EwlYaGoKl9kwdB3SW-shNw1DOg7qmOZwU0K15aC2HNWWo9o6pLsRv6ypQf4l-BaVmmPIgP2Majof4FRIvpUPRCQQ1ClAcq8lCa5u2strs8ibULPIt47RIa82y_glwudKO1uiTII8Q1APdsjj2oo2R44RDxGzpENky742AkhA3l4pJ-eeiFzAXRm-ffr_Y70kt8BT86-Hx0fPyG2G7xUe9b5Hdqv50j6Hoq7SL7z3UHJ23e76B9LxZGY |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Garlic+lowers+blood+pressure+in+hypertensive+subjects%2C+improves+arterial+stiffness+and+gut+microbiota%3A+A+review+and+meta-analysis&rft.jtitle=Experimental+and+therapeutic+medicine&rft.au=Ried%2C+Karin&rft.date=2020-02-01&rft.issn=1792-0981&rft.volume=19&rft.issue=2&rft.spage=1472&rft_id=info:doi/10.3892%2Fetm.2019.8374&rft.externalDBID=NO_FULL_TEXT |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=1792-0981&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=1792-0981&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=1792-0981&client=summon |