Changes of Th17/Treg ratio in the transition of chronic hepatitis B to liver cirrhosis and correlations with liver function and inflammation

• Published in: Experimental and therapeutic medicine Vol. 17; no. 4; pp. 2963 - 2968
• Main Authors: Mou, Haijuan, Wu, Song, Zhao, Guang, Wang, Jindong
• Format: Journal Article
• Language: English
• Published: Greece Spandidos Publications 01.04.2019; Spandidos Publications UK Ltd; D.A. Spandidos
• Subjects: Biotechnology; Cytokines; Dehydrogenases; Diagnosis; Hepatitis; Hepatitis B; Hospitals; Infectious diseases; Inflammation; Interleukins; Liver cancer; Liver cirrhosis; Liver diseases; Messenger RNA; Necrosis; Polymerase chain reaction; RNA; Sediments; T cells; Tumor necrosis factor-TNF; Tumors; United States > US; China; chronic hepatitis B; inflammation; Th17/Treg; liver cirrhosis; liver function
• ISSN: 1792-0981; 1792-1015
• DOI: 10.3892/etm.2019.7299

The changes in ratio of T helper 17 cells (Th17) to Treg cells in the transition of chronic hepatitis B (CHB) to liver cirrhosis, and the correlations with liver function and inflammation were investigated. A total of 20 normal subjects (control group), 35 CHB patients (CHB group) and 40 post-hepati...