Cellular and Molecular Targets for Non-Invasive, Non-Pharmacological Therapeutic/Rehabilitative Interventions in Acute Ischemic Stroke

• Published in: International journal of molecular sciences Vol. 23; no. 2; p. 907
• Main Authors: Onose, Gelu, Anghelescu, Aurelian, Blendea, Dan, Ciobanu, Vlad, Daia, Cristina, Firan, Florentina, Oprea, Mihaela, Spinu, Aura, Popescu, Cristina, Ionescu, Anca, Busnatu, Ștefan, Munteanu, Constantin
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 14.01.2022; MDPI
• Subjects: Acupuncture; Biomarkers; Brain - blood supply; Brain - metabolism; Brain - pathology; Clinical Decision-Making; Clinical trials; Combined Modality Therapy; Cytokines - metabolism; Disease Management; Disease Susceptibility; Embolisms; Gene Expression Regulation; Growth factors; Humans; Hypothermia; Inflammation Mediators - metabolism; Ischemia; Ischemic Stroke - etiology; Ischemic Stroke - metabolism; Ischemic Stroke - rehabilitation; Ischemic Stroke - therapy; Literature reviews; Neovascularization, Pathologic; Oxidative Stress; Physiology; Review; Signal Transduction; Stroke; Systematic review; non-invasive; brain repair; neuroregeneration; neurorestorative; non-pharmacological interventions; systematic review; cellular and molecular targets

BACKGROUND: Cerebral circulation delivers the blood flow to the brain through a dedicated network of sanguine vessels. A healthy human brain can regulate cerebral blood flow (CBF) according to any physiological or pathological challenges. The brain is protected by its self-regulatory mechanisms, whi...