VarEPS: an evaluation and prewarning system of known and virtual variations of SARS-CoV-2 genomes

• Published in: Nucleic acids research Vol. 50; no. D1; pp. D888 - D897
• Main Authors: Sun, Qinglan, Shu, Chang, Shi, Wenyu, Luo, Yingfeng, Fan, Guomei, Nie, Jingyi, Bi, Yuhai, Wang, Qihui, Qi, Jianxun, Lu, Jian, Zhou, Yuanchun, Shen, Zhihong, Meng, Zhen, Zhang, Xinjiao, Yu, Zhengfei, Gao, Shenghan, Wu, Linhuan, Ma, Juncai, Hu, Songnian
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 07.01.2022
• Subjects: Algorithms; Angiotensin-Converting Enzyme 2 - metabolism; Antibodies, Neutralizing - metabolism; Artificial Intelligence; COVID-19 - virology; Database Issue; Databases, Factual; DNA Primers; Genome, Viral; Humans; Mutation; SARS-CoV-2 - genetics

Abstract The genomic variations of SARS-CoV-2 continue to emerge and spread worldwide. Some mutant strains show increased transmissibility and virulence, which may cause reduced protection provided by vaccines. Thus, it is necessary to continuously monitor and analyze the genomic variations of SARS-...