Endovascular thrombectomy for childhood stroke (Save ChildS Pro): an international, multicentre, prospective registry study
Emerging evidence suggests that endovascular thrombectomy is beneficial for treatment of childhood stroke, but the safety and effectiveness of endovascular thrombectomy has not been compared with best medical treatment. We aimed to prospectively analyse functional outcomes of endovascular thrombecto...
Saved in:
| Published in | The lancet child & adolescent health Vol. 8; no. 12; pp. 882 - 890 |
|---|---|
| Main Authors | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
England
Elsevier Ltd
01.12.2024
|
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | Emerging evidence suggests that endovascular thrombectomy is beneficial for treatment of childhood stroke, but the safety and effectiveness of endovascular thrombectomy has not been compared with best medical treatment. We aimed to prospectively analyse functional outcomes of endovascular thrombectomy versus best medical treatment in children with intracranial arterial occlusion stroke.
In this prospective registry study, 45 centres in 12 countries across Asia and Australia, Europe, North America, and South America reported functional outcomes for children aged between 28 days and 18 years presenting with arterial ischaemic stroke caused by a large-vessel or medium-vessel occlusion who received either endovascular thrombectomy plus best medical practice or best medical treatment alone. Intravenous thrombolysis was considered part of best medical treatment and therefore permitted in both groups. The primary outcome was the difference in median modified Rankin Scale (mRS) score between baseline (pre-stroke) and 90 days (±10 days) post-stroke, assessed by the Wilcoxon rank test (α=0·05). Efficacy outcomes in the endovascular thrombectomy and best medical treatment groups were compared in sensitivity analyses using propensity score matching. The Save ChildS Pro study is registered at the German Clinical Trials Registry, DRKS00018960.
Between Jan 1, 2020, and Aug 31, 2023, of the 241 patients in the Save ChildS Pro registry, 208 were included in the analysis (115 [55%] boys and 93 [45%] girls). 117 patients underwent endovascular thrombectomy (median age 11 years [IQR 6–14]), and 91 patients received best medical treatment (6 years [3–12]; p<0·0001). The median Pediatric National Institutes of Health Stroke Scale (PedNIHSS) score on admission was 14 (IQR 10–19) in the endovascular thrombectomy group and 9 (5–13) in the best medical treatment group (p<0·0001). Both treatment groups had a median pre-stroke mRS score of 0 (IQR 0–0) at baseline. The change in median mRS score between baseline and 90 days was 1 (IQR 0–2) in the endovascular thrombectomy group and 2 (1–3) in the best medical treatment group (p=0·020). One (1%) patient developed a symptomatic intracranial haemorrhage (this patient was in the endovascular thrombectomy group). Six (5%) patients in the endovascular thrombectomy group and four (5%) patients in the best medical treatment group had died by day 90 (p=0·89). After propensity score matching for age, sex, and PedNIHSS score at hospital admission (n=79 from each group), the change in median mRS score between baseline and 90 days was 1 (IQR 0–2) in the endovascular thrombectomy group and 2 (1–3) in the best medical treatment group (p=0·029). Regarding the primary outcome for patients with suspected focal cerebral arteriopathy, endovascular thrombectomy (n=18) and best medical treatment (n=33) showed no difference in 90-day median mRS scores (2 [IQR 1–3] vs 2 [1–4]; p=0·074).
Clinical centres tended to select children with more severe strokes (higher PedNIHSS score) for endovascular thrombectomy. Nevertheless, endovascular thrombectomy was associated with improved functional outcomes in paediatric patients with large-vessel or medium-vessel occlusions compared with best medical treatment. Future studies need to investigate whether the positive effect of endovascular thrombectomy is confined to older and more severely affected children.
None. |
|---|---|
| AbstractList | Emerging evidence suggests that endovascular thrombectomy is beneficial for treatment of childhood stroke, but the safety and effectiveness of endovascular thrombectomy has not been compared with best medical treatment. We aimed to prospectively analyse functional outcomes of endovascular thrombectomy versus best medical treatment in children with intracranial arterial occlusion stroke.BACKGROUNDEmerging evidence suggests that endovascular thrombectomy is beneficial for treatment of childhood stroke, but the safety and effectiveness of endovascular thrombectomy has not been compared with best medical treatment. We aimed to prospectively analyse functional outcomes of endovascular thrombectomy versus best medical treatment in children with intracranial arterial occlusion stroke.In this prospective registry study, 45 centres in 12 countries across Asia and Australia, Europe, North America, and South America reported functional outcomes for children aged between 28 days and 18 years presenting with arterial ischaemic stroke caused by a large-vessel or medium-vessel occlusion who received either endovascular thrombectomy plus best medical practice or best medical treatment alone. Intravenous thrombolysis was considered part of best medical treatment and therefore permitted in both groups. The primary outcome was the difference in median modified Rankin Scale (mRS) score between baseline (pre-stroke) and 90 days (±10 days) post-stroke, assessed by the Wilcoxon rank test (α=0·05). Efficacy outcomes in the endovascular thrombectomy and best medical treatment groups were compared in sensitivity analyses using propensity score matching. The Save ChildS Pro study is registered at the German Clinical Trials Registry, DRKS00018960.METHODSIn this prospective registry study, 45 centres in 12 countries across Asia and Australia, Europe, North America, and South America reported functional outcomes for children aged between 28 days and 18 years presenting with arterial ischaemic stroke caused by a large-vessel or medium-vessel occlusion who received either endovascular thrombectomy plus best medical practice or best medical treatment alone. Intravenous thrombolysis was considered part of best medical treatment and therefore permitted in both groups. The primary outcome was the difference in median modified Rankin Scale (mRS) score between baseline (pre-stroke) and 90 days (±10 days) post-stroke, assessed by the Wilcoxon rank test (α=0·05). Efficacy outcomes in the endovascular thrombectomy and best medical treatment groups were compared in sensitivity analyses using propensity score matching. The Save ChildS Pro study is registered at the German Clinical Trials Registry, DRKS00018960.Between Jan 1, 2020, and Aug 31, 2023, of the 241 patients in the Save ChildS Pro registry, 208 were included in the analysis (115 [55%] boys and 93 [45%] girls). 117 patients underwent endovascular thrombectomy (median age 11 years [IQR 6-14]), and 91 patients received best medical treatment (6 years [3-12]; p<0·0001). The median Pediatric National Institutes of Health Stroke Scale (PedNIHSS) score on admission was 14 (IQR 10-19) in the endovascular thrombectomy group and 9 (5-13) in the best medical treatment group (p<0·0001). Both treatment groups had a median pre-stroke mRS score of 0 (IQR 0-0) at baseline. The change in median mRS score between baseline and 90 days was 1 (IQR 0-2) in the endovascular thrombectomy group and 2 (1-3) in the best medical treatment group (p=0·020). One (1%) patient developed a symptomatic intracranial haemorrhage (this patient was in the endovascular thrombectomy group). Six (5%) patients in the endovascular thrombectomy group and four (5%) patients in the best medical treatment group had died by day 90 (p=0·89). After propensity score matching for age, sex, and PedNIHSS score at hospital admission (n=79 from each group), the change in median mRS score between baseline and 90 days was 1 (IQR 0-2) in the endovascular thrombectomy group and 2 (1-3) in the best medical treatment group (p=0·029). Regarding the primary outcome for patients with suspected focal cerebral arteriopathy, endovascular thrombectomy (n=18) and best medical treatment (n=33) showed no difference in 90-day median mRS scores (2 [IQR 1-3] vs 2 [1-4]; p=0·074).FINDINGSBetween Jan 1, 2020, and Aug 31, 2023, of the 241 patients in the Save ChildS Pro registry, 208 were included in the analysis (115 [55%] boys and 93 [45%] girls). 117 patients underwent endovascular thrombectomy (median age 11 years [IQR 6-14]), and 91 patients received best medical treatment (6 years [3-12]; p<0·0001). The median Pediatric National Institutes of Health Stroke Scale (PedNIHSS) score on admission was 14 (IQR 10-19) in the endovascular thrombectomy group and 9 (5-13) in the best medical treatment group (p<0·0001). Both treatment groups had a median pre-stroke mRS score of 0 (IQR 0-0) at baseline. The change in median mRS score between baseline and 90 days was 1 (IQR 0-2) in the endovascular thrombectomy group and 2 (1-3) in the best medical treatment group (p=0·020). One (1%) patient developed a symptomatic intracranial haemorrhage (this patient was in the endovascular thrombectomy group). Six (5%) patients in the endovascular thrombectomy group and four (5%) patients in the best medical treatment group had died by day 90 (p=0·89). After propensity score matching for age, sex, and PedNIHSS score at hospital admission (n=79 from each group), the change in median mRS score between baseline and 90 days was 1 (IQR 0-2) in the endovascular thrombectomy group and 2 (1-3) in the best medical treatment group (p=0·029). Regarding the primary outcome for patients with suspected focal cerebral arteriopathy, endovascular thrombectomy (n=18) and best medical treatment (n=33) showed no difference in 90-day median mRS scores (2 [IQR 1-3] vs 2 [1-4]; p=0·074).Clinical centres tended to select children with more severe strokes (higher PedNIHSS score) for endovascular thrombectomy. Nevertheless, endovascular thrombectomy was associated with improved functional outcomes in paediatric patients with large-vessel or medium-vessel occlusions compared with best medical treatment. Future studies need to investigate whether the positive effect of endovascular thrombectomy is confined to older and more severely affected children.INTERPRETATIONClinical centres tended to select children with more severe strokes (higher PedNIHSS score) for endovascular thrombectomy. Nevertheless, endovascular thrombectomy was associated with improved functional outcomes in paediatric patients with large-vessel or medium-vessel occlusions compared with best medical treatment. Future studies need to investigate whether the positive effect of endovascular thrombectomy is confined to older and more severely affected children.None.FUNDINGNone. Emerging evidence suggests that endovascular thrombectomy is beneficial for treatment of childhood stroke, but the safety and effectiveness of endovascular thrombectomy has not been compared with best medical treatment. We aimed to prospectively analyse functional outcomes of endovascular thrombectomy versus best medical treatment in children with intracranial arterial occlusion stroke. In this prospective registry study, 45 centres in 12 countries across Asia and Australia, Europe, North America, and South America reported functional outcomes for children aged between 28 days and 18 years presenting with arterial ischaemic stroke caused by a large-vessel or medium-vessel occlusion who received either endovascular thrombectomy plus best medical practice or best medical treatment alone. Intravenous thrombolysis was considered part of best medical treatment and therefore permitted in both groups. The primary outcome was the difference in median modified Rankin Scale (mRS) score between baseline (pre-stroke) and 90 days (±10 days) post-stroke, assessed by the Wilcoxon rank test (α=0·05). Efficacy outcomes in the endovascular thrombectomy and best medical treatment groups were compared in sensitivity analyses using propensity score matching. The Save ChildS Pro study is registered at the German Clinical Trials Registry, DRKS00018960. Between Jan 1, 2020, and Aug 31, 2023, of the 241 patients in the Save ChildS Pro registry, 208 were included in the analysis (115 [55%] boys and 93 [45%] girls). 117 patients underwent endovascular thrombectomy (median age 11 years [IQR 6-14]), and 91 patients received best medical treatment (6 years [3-12]; p<0·0001). The median Pediatric National Institutes of Health Stroke Scale (PedNIHSS) score on admission was 14 (IQR 10-19) in the endovascular thrombectomy group and 9 (5-13) in the best medical treatment group (p<0·0001). Both treatment groups had a median pre-stroke mRS score of 0 (IQR 0-0) at baseline. The change in median mRS score between baseline and 90 days was 1 (IQR 0-2) in the endovascular thrombectomy group and 2 (1-3) in the best medical treatment group (p=0·020). One (1%) patient developed a symptomatic intracranial haemorrhage (this patient was in the endovascular thrombectomy group). Six (5%) patients in the endovascular thrombectomy group and four (5%) patients in the best medical treatment group had died by day 90 (p=0·89). After propensity score matching for age, sex, and PedNIHSS score at hospital admission (n=79 from each group), the change in median mRS score between baseline and 90 days was 1 (IQR 0-2) in the endovascular thrombectomy group and 2 (1-3) in the best medical treatment group (p=0·029). Regarding the primary outcome for patients with suspected focal cerebral arteriopathy, endovascular thrombectomy (n=18) and best medical treatment (n=33) showed no difference in 90-day median mRS scores (2 [IQR 1-3] vs 2 [1-4]; p=0·074). Clinical centres tended to select children with more severe strokes (higher PedNIHSS score) for endovascular thrombectomy. Nevertheless, endovascular thrombectomy was associated with improved functional outcomes in paediatric patients with large-vessel or medium-vessel occlusions compared with best medical treatment. Future studies need to investigate whether the positive effect of endovascular thrombectomy is confined to older and more severely affected children. None. |
| Author | Fullerton, Heather J Wang, Furene Orlov, Kirill Grieb, Dominik Tomek, Ales Wendl, Christina Liebig, Thomas Möhlenbruch, Markus Abruzzo, Todd Gersing, Alexandra S Naggara, Olivier Lee, Sarah Psychogios, Marios-Nikos Lo, Warren Kleffner, Ilka Schob, Stefan Fox, Christine K Brechbühl, Daniel Limbucci, Nicola Parra-Farinas, Carmen Kraehling, Hermann Alawieh, Ali Jensen-Kondering, Ulf Regenhardt, Robert W Marik, Wolfgang Kaiser, Daniel P O Kauffmann, Birgit Musolino, Patricia Fraser, Stuart Chung, Melissa G Burkard, Tanja Chapot, René Pabst, Lisa Hafeez, Muhammad Ubaid Muthusami, Prakash Wilson, Jenny Schwabova, Jaroslava Paulasova Yilmaz, Umut Henkes, Hans Nguyen-Kim, Thi Dan Linh Martinez, Mesha Bhatia, Kartik Kuznetsova, Alexandra Dmytriw, Adam A Fiehler, Jens Papanagiotou, Panagiotis Requejo, Flavio Othman, Ahmed Steinmetz, Sebastian Schellinger, Peter D Hassan, Ameer E Kemmling, André Sporns, Peter B Olivieri, Martin Wildgruber, Moritz Boulouis, Grégoire Steinlin, Maja Sun, Lisa R Nikoubashman, Omid |
| Author_xml | – sequence: 1 givenname: Peter B surname: Sporns fullname: Sporns, Peter B email: peter.sporns@hotmail.de organization: Department of Neuroradiology, University Hospital Basel, Basel, Switzerland – sequence: 2 givenname: Kartik surname: Bhatia fullname: Bhatia, Kartik organization: Department of Medical Imaging, Children's Hospital at Westmead, Sydney, NSW, Australia – sequence: 3 givenname: Todd surname: Abruzzo fullname: Abruzzo, Todd organization: Department of Neurosurgery, Barrow Neurological Institute, Phoenix, AZ, USA – sequence: 4 givenname: Lisa surname: Pabst fullname: Pabst, Lisa organization: Division of Pediatric Neurology, Department of Pediatrics, University of Utah School of Medicine, Salt Lake City, UT, USA – sequence: 5 givenname: Stuart surname: Fraser fullname: Fraser, Stuart organization: Division of Child and Adolescent Neurology, Department of Pediatrics, The University of Texas McGovern Medical School, Houston, TX, USA – sequence: 6 givenname: Melissa G surname: Chung fullname: Chung, Melissa G organization: Division of Critical Care Medicine and Division of Pediatric Neurology, Department of Pediatrics, Nationwide Children's Hospital and The Ohio State University, Columbus, OH, USA – sequence: 7 givenname: Warren surname: Lo fullname: Lo, Warren organization: Department of Pediatrics and Department of Neurology, Nationwide Children's Hospital and The Ohio State University, Columbus, OH, USA – sequence: 8 givenname: Ahmed surname: Othman fullname: Othman, Ahmed organization: Department of Neuroradiology, University Medical Center of the Johannes Gutenberg University, Mainz, Germany – sequence: 9 givenname: Sebastian surname: Steinmetz fullname: Steinmetz, Sebastian organization: Department of Neuroradiology, University Medical Center of the Johannes Gutenberg University, Mainz, Germany – sequence: 10 givenname: Ulf surname: Jensen-Kondering fullname: Jensen-Kondering, Ulf organization: Department of Radiology and Neuroradiology, University Medical Center Schleswig-Holstein, Kiel, Germany – sequence: 11 givenname: Stefan surname: Schob fullname: Schob, Stefan organization: Department of Radiology and Neuroradiology, University Hospital Halle, Halle, Germany – sequence: 12 givenname: Daniel P O surname: Kaiser fullname: Kaiser, Daniel P O organization: Institute of Neuroradiology, Medical Faculty and University Hospital Carl Gustav Carus, Dresden University of Technology, Dresden, Germany – sequence: 13 givenname: Wolfgang surname: Marik fullname: Marik, Wolfgang organization: Department of Neuroradiology, Medical University of Vienna, Vienna, Austria – sequence: 14 givenname: Christina surname: Wendl fullname: Wendl, Christina organization: Institute of Radiology, University Hospital Regensburg, Regensburg, Germany – sequence: 15 givenname: Ilka surname: Kleffner fullname: Kleffner, Ilka organization: Department of Neurology, University Hospital Knappschaftskrankenhaus, Ruhr University Bochum, Bochum, Germany – sequence: 16 givenname: Hans surname: Henkes fullname: Henkes, Hans organization: Neuroradiological Clinic, Katharinenhospital, Klinikum Stuttgart, Stuttgart, Germany – sequence: 17 givenname: Hermann surname: Kraehling fullname: Kraehling, Hermann organization: Clinic for Radiology, Department for Interventional Neuroradiology, University of Münster, Münster, Germany – sequence: 18 givenname: Thi Dan Linh surname: Nguyen-Kim fullname: Nguyen-Kim, Thi Dan Linh organization: Department of Radiology and Neuroradiology, Stadtspital Zürich, Zürich, Switzerland – sequence: 19 givenname: René surname: Chapot fullname: Chapot, René organization: Department of Neuroradiology, Alfried-Krupp-Krankenhaus, Essen, Germany – sequence: 20 givenname: Umut surname: Yilmaz fullname: Yilmaz, Umut organization: Department of Neuroradiology, Saarland University Hospital, Homburg, Germany – sequence: 21 givenname: Furene surname: Wang fullname: Wang, Furene organization: Department of Paediatrics, Khoo Teck Puat-National University Children's Medical Institute, National University Hospital, Singapore – sequence: 22 givenname: Muhammad Ubaid surname: Hafeez fullname: Hafeez, Muhammad Ubaid organization: Department of Neurology, Baylor College of Medicine, Houston, TX, USA – sequence: 23 givenname: Flavio surname: Requejo fullname: Requejo, Flavio organization: Department of Neuroradiology, Hospital de Pediatría J.P. Garrahan, Buenos Aires, Argentina – sequence: 24 givenname: Nicola surname: Limbucci fullname: Limbucci, Nicola organization: Department of Interventional Neuroradiology, Careggi University Hospital, Florence, Italy – sequence: 25 givenname: Birgit surname: Kauffmann fullname: Kauffmann, Birgit organization: Department of Pediatrics and Adolescent Medicine, Eltern-Kind-Zentrum Prof Hess, Klinikum Bremen Mitte, Bremen, Germany – sequence: 26 givenname: Markus surname: Möhlenbruch fullname: Möhlenbruch, Markus organization: Department of Neuroradiology, Heidelberg University Hospital, Heidelberg, Germany – sequence: 27 givenname: Omid surname: Nikoubashman fullname: Nikoubashman, Omid organization: Department of Neuroradiology, Aachen University, Aachen, Germany – sequence: 28 givenname: Peter D surname: Schellinger fullname: Schellinger, Peter D organization: Department of Neurology and Neurogeriatrics, University Clinic of the Ruhr-Universität Bochum, Minden, Germany – sequence: 29 givenname: Patricia surname: Musolino fullname: Musolino, Patricia organization: Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA – sequence: 30 givenname: Ali surname: Alawieh fullname: Alawieh, Ali organization: Department of Neurosurgery, Emory University School of Medicine, Atlanta, GA, USA – sequence: 31 givenname: Jenny surname: Wilson fullname: Wilson, Jenny organization: Division of Pediatric Neurology, Oregon Health & Science University, Portland, OR, USA – sequence: 32 givenname: Dominik surname: Grieb fullname: Grieb, Dominik organization: Department of Radiology and Neuroradiology, Sana Kliniken Duisburg, Duisburg, Germany – sequence: 33 givenname: Alexandra S surname: Gersing fullname: Gersing, Alexandra S organization: Department of Neuroradiology, LMU University Hospital, LMU Munich, Munich, Germany – sequence: 34 givenname: Thomas surname: Liebig fullname: Liebig, Thomas organization: Department of Neuroradiology, LMU University Hospital, LMU Munich, Munich, Germany – sequence: 35 givenname: Martin surname: Olivieri fullname: Olivieri, Martin organization: Pediatric Thrombosis and Hemostasis Unit, Dr von Hauner Children's Hospital, LMU Munich, Munich, Germany – sequence: 36 givenname: Jaroslava Paulasova surname: Schwabova fullname: Schwabova, Jaroslava Paulasova organization: Department of Paediatric Neurology, Comprehensive Stroke Center, Second Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic – sequence: 37 givenname: Ales surname: Tomek fullname: Tomek, Ales organization: Department of Neurology, Comprehensive Stroke Center, Second Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic – sequence: 38 givenname: Panagiotis surname: Papanagiotou fullname: Papanagiotou, Panagiotis organization: Department of Diagnostic and Interventional Neuroradiology, Hospital Bremen-Mitte/Bremen-Ost, Bremen, Germany – sequence: 39 givenname: Grégoire surname: Boulouis fullname: Boulouis, Grégoire organization: Diagnostic and Interventional Neuroradiology Department, University Hospital of Tours, Tours, France – sequence: 40 givenname: Olivier surname: Naggara fullname: Naggara, Olivier organization: French Center for Pediatric Stroke, Paris, France – sequence: 41 givenname: Christine K surname: Fox fullname: Fox, Christine K organization: Department of Neurology and Department of Pediatrics, University of California San Francisco, San Francisco, CA, USA – sequence: 42 givenname: Kirill surname: Orlov fullname: Orlov, Kirill organization: Research Center of Endovascular Neurosurgery, Federal Center of Brain Research and Neuro Technologies of FMBA, Moscow, Russia – sequence: 43 givenname: Alexandra surname: Kuznetsova fullname: Kuznetsova, Alexandra organization: Morozov Moscow Children Clinical Hospital, Moscow, Russia – sequence: 44 givenname: Carmen surname: Parra-Farinas fullname: Parra-Farinas, Carmen organization: Division of Neuroradiology and Division of Neurointervention, Hospital for Sick Children, University of Toronto, Toronto, ON, Canada – sequence: 45 givenname: Prakash surname: Muthusami fullname: Muthusami, Prakash organization: Division of Neuroradiology and Division of Neurointervention, Hospital for Sick Children, University of Toronto, Toronto, ON, Canada – sequence: 46 givenname: Robert W surname: Regenhardt fullname: Regenhardt, Robert W organization: Neuroendovascular Program, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA – sequence: 47 givenname: Adam A surname: Dmytriw fullname: Dmytriw, Adam A organization: Neuroendovascular Program, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA – sequence: 48 givenname: Tanja surname: Burkard fullname: Burkard, Tanja organization: Department of Radiology, LMU University Hospital, LMU Munich, Munich, Germany – sequence: 49 givenname: Mesha surname: Martinez fullname: Martinez, Mesha organization: University Hospital, LMU Munich, Germany – sequence: 50 givenname: Daniel surname: Brechbühl fullname: Brechbühl, Daniel organization: Division of Neuropaediatrics, Development and Rehabilitation, Department of Paediatrics, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland – sequence: 51 givenname: Maja surname: Steinlin fullname: Steinlin, Maja organization: Division of Neuropaediatrics, Development and Rehabilitation, Department of Paediatrics, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland – sequence: 52 givenname: Lisa R surname: Sun fullname: Sun, Lisa R organization: Department of Neurology, Johns Hopkins School of Medicine, Baltimore, MD, USA – sequence: 53 givenname: Ameer E surname: Hassan fullname: Hassan, Ameer E organization: Department of Neurology, University of Texas Rio Grande Valley, Harlingen, TX, USA – sequence: 54 givenname: André surname: Kemmling fullname: Kemmling, André organization: Department of Neuroradiology, University of Marburg, Marburg, Germany – sequence: 55 givenname: Sarah surname: Lee fullname: Lee, Sarah organization: Division of Child Neurology, Department of Neurology, Stanford University, Stanford, CA, USA – sequence: 56 givenname: Heather J surname: Fullerton fullname: Fullerton, Heather J organization: Department of Neurology and Department of Pediatrics, University of California San Francisco, San Francisco, CA, USA – sequence: 57 givenname: Jens surname: Fiehler fullname: Fiehler, Jens organization: Department of Diagnostic and Interventional Neuroradiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany – sequence: 58 givenname: Marios-Nikos surname: Psychogios fullname: Psychogios, Marios-Nikos organization: Department of Neuroradiology, University Hospital Basel, Basel, Switzerland – sequence: 59 givenname: Moritz surname: Wildgruber fullname: Wildgruber, Moritz organization: Department of Radiology, LMU University Hospital, LMU Munich, Munich, Germany |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/39401507$$D View this record in MEDLINE/PubMed |
| BookMark | eNqFUcluFDEUtFAQCSGfAPJxIqXBay_kgNAoLFIkkCZ3y22_Zgzd9mC7Rxrx83iWcOCSk63nqnquqpfozAcPCL2m5C0ltH63YlyyStSCLZi4JoRxXsln6OI0luTs312wc3SV0k9CCG1b2hDxAp3zThAqSXOB_tx5G7Y6mXnUEed1DFMPJodph4cQsVm70a5DsDjlGH4BXqz0FvByP17h7zFcv8faY-czRK-zC16PN3iax-wM-BzhBm9iSJsi6Qovwg9XhHZFbba7V-j5oMcEV6fzEj18untYfqnuv33-uvx4XxlBWa7oAHKoO85ZL2BoG2N71hczpOl130lbE00M1bYrvjXUdXluNBnajgNY0_BLtDjKlp_8niFlNblkYBy1hzAnxSmt60ZK0hbomxN07iewahPdpONOPeZVALdHgCmuUoRBGZcPvnPUblSUqH1B6lCQ2qevmFCHgpQsbPkf-3HBU7wPRx6UlLYOokrGgTdgXSzJKhvcEwp_AccaqZc |
| CitedBy_id | crossref_primary_10_1016_j_pediatrneurol_2025_01_004 crossref_primary_10_1016_S2352_4642_24_00257_8 crossref_primary_10_1055_a_2503_3994 |
| Cites_doi | 10.1002/ana.10423 10.1016/S2352-4642(21)00167-X 10.1161/JAHA.118.011335 10.1038/s41572-022-00337-x 10.3389/fneur.2021.736092 10.1159/000441087 10.1212/WNL.0000000000011107 10.1111/dmcn.12092 10.1212/WNL.59.1.34 10.1212/WNL.0000000000013081 10.3171/2019.5.PEDS19126 10.1161/STROKEAHA.118.023060 10.1016/S0140-6736(16)00163-X 10.1038/nrneurol.2009.228 10.1001/jamaneurol.2023.2303 10.1016/S0140-6736(23)02032-9 10.1161/STROKEAHA.119.028221 10.1001/jamanetworkopen.2022.31343 10.3389/fneur.2021.790486 10.1161/STROKEAHA.120.031133 10.1161/STROKEAHA.114.008210 10.1001/jamaneurol.2022.0323 10.1177/1756286421998905 10.1056/NEJMoa1706442 10.1161/STROKEAHA.111.624585 10.1007/s00062-020-00988-x 10.1111/j.1469-8749.2009.03425.x 10.1016/j.pediatrneurol.2023.01.009 10.1016/S0140-6736(23)01142-X 10.1001/jamaneurol.2019.3403 10.1136/svn-2022-002257 10.1016/j.jpeds.2019.09.027 |
| ContentType | Journal Article |
| Copyright | 2024 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license Copyright © 2024 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license. Published by Elsevier Ltd.. All rights reserved. |
| Copyright_xml | – notice: 2024 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license – notice: Copyright © 2024 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license. Published by Elsevier Ltd.. All rights reserved. |
| DBID | 6I. AAFTH AAYXX CITATION CGR CUY CVF ECM EIF NPM 7X8 |
| DOI | 10.1016/S2352-4642(24)00233-5 |
| DatabaseName | ScienceDirect Open Access Titles Elsevier:ScienceDirect:Open Access CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed MEDLINE - Academic |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) MEDLINE - Academic |
| DatabaseTitleList | MEDLINE - Academic MEDLINE |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Medicine |
| EISSN | 2352-4650 |
| EndPage | 890 |
| ExternalDocumentID | 39401507 10_1016_S2352_4642_24_00233_5 S2352464224002335 |
| Genre | Clinical Trial Multicenter Study Journal Article |
| GrantInformation | None. |
| GroupedDBID | 0R~ 53G 6I. AAEDW AAFTH AALRI AAMRU AAQFI AAXUO ABMAC ADBBV ADVLN AFTJW AITUG AKRWK ALMA_UNASSIGNED_HOLDINGS AMRAJ EBS EJD FDB HX~ K-O ROL AAYWO AAYXX ACVFH ADCNI AEUPX AFPUW AGCQF AIGII AKBMS AKYEP APXCP CITATION CGR CUY CVF ECM EIF NPM 7X8 |
| ID | FETCH-LOGICAL-c412t-1fe5f69332b4ef87cdb2b01807bab95d60a0c1ad9650ae66db27a0f893eedc73 |
| ISSN | 2352-4642 2352-4650 |
| IngestDate | Fri Jul 11 12:07:31 EDT 2025 Thu May 22 05:05:13 EDT 2025 Thu Apr 24 23:00:55 EDT 2025 Tue Jul 01 00:54:50 EDT 2025 Sat Nov 23 15:53:53 EST 2024 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 12 |
| Language | English |
| License | This is an open access article under the CC BY license. Copyright © 2024 The Author(s). Published by Elsevier Ltd. This is an Open Access article under the CC BY 4.0 license. Published by Elsevier Ltd.. All rights reserved. |
| LinkModel | OpenURL |
| MergedId | FETCHMERGED-LOGICAL-c412t-1fe5f69332b4ef87cdb2b01807bab95d60a0c1ad9650ae66db27a0f893eedc73 |
| Notes | ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 |
| OpenAccessLink | https://dx.doi.org/10.1016/S2352-4642(24)00233-5 |
| PMID | 39401507 |
| PQID | 3116675508 |
| PQPubID | 23479 |
| PageCount | 9 |
| ParticipantIDs | proquest_miscellaneous_3116675508 pubmed_primary_39401507 crossref_citationtrail_10_1016_S2352_4642_24_00233_5 crossref_primary_10_1016_S2352_4642_24_00233_5 elsevier_sciencedirect_doi_10_1016_S2352_4642_24_00233_5 |
| ProviderPackageCode | CITATION AAYXX |
| PublicationCentury | 2000 |
| PublicationDate | December 2024 2024-12-00 20241201 |
| PublicationDateYYYYMMDD | 2024-12-01 |
| PublicationDate_xml | – month: 12 year: 2024 text: December 2024 |
| PublicationDecade | 2020 |
| PublicationPlace | England |
| PublicationPlace_xml | – name: England |
| PublicationTitle | The lancet child & adolescent health |
| PublicationTitleAlternate | Lancet Child Adolesc Health |
| PublicationYear | 2024 |
| Publisher | Elsevier Ltd |
| Publisher_xml | – name: Elsevier Ltd |
| References | Tan, Zhang, Huang (bib30) 2024; 9 Ganesan, Prengler, McShane, Wade, Kirkham (bib2) 2003; 53 Sporns, Psychogios, Straeter (bib10) 2021; 96 Sporns, Kemmling, Lee (bib13) 2021; 12 Stracke, Meyer, Schwindt, Ranft, Straeter (bib26) 2022; 12 deVeber (bib18) 2010; 6 Rivkin, deVeber, Ichord (bib5) 2015; 46 Sporns, Fiehler, Ospel (bib22) 2021; 14 Harrar, Salussolia, Kapur (bib17) 2020; 216 Bhatia, Briest, Goetti (bib15) 2022; 79 Bhatia, Chowdhury, Andrews (bib16) 2023; 80 Feldman, Beslow, Felling (bib31) 2023; 141 Chabrier, Ozanne, Naggara, Boulouis, Husson, Kossorotoff (bib11) 2021; 52 Lagman-Bartolome, Pontigon, Moharir (bib19) 2013; 55 Bhatia, Kortman, Blair (bib7) 2019; 24 Fullerton, Chetkovich, Wu, Smith, Johnston (bib3) 2002; 59 Sporns, Fullerton, Lee (bib1) 2022; 8 van Horn, Kniep, Broocks (bib28) 2021; 31 Nogueira, Jadhav, Haussen (bib32) 2018; 378 Böhmer, Niederstadt, Heindel (bib21) 2019; 50 Sporns, Fullerton, Lee, Kirton, Wildgruber (bib14) 2021; 5 Krishnamurthi, deVeber, Feigin (bib4) 2015; 45 Lee, Jiang, Wintermark (bib25) 2022; 98 Majoie, Cavalcante, Gralla (bib29) 2023; 402 Bernard, Manco-Johnson, Lo (bib20) 2012; 43 Bendszus, Fiehler, Subtil (bib23) 2023; 402 Wittenberg (bib24) 2009; 51 Kossorotoff, Kerleroux, Boulouis (bib12) 2022; 5 Sporns, Straeter, Minnerup (bib9) 2020; 51 Sporns, Sträter, Minnerup (bib8) 2020; 77 Goyal, Menon, van Zwam (bib6) 2016; 387 Bhatia (10.1016/S2352-4642(24)00233-5_bib16) 2023; 80 Feldman (10.1016/S2352-4642(24)00233-5_bib31) 2023; 141 Nogueira (10.1016/S2352-4642(24)00233-5_bib32) 2018; 378 Krishnamurthi (10.1016/S2352-4642(24)00233-5_bib4) 2015; 45 Sporns (10.1016/S2352-4642(24)00233-5_bib14) 2021; 5 Sporns (10.1016/S2352-4642(24)00233-5_bib9) 2020; 51 Sporns (10.1016/S2352-4642(24)00233-5_bib1) 2022; 8 Sporns (10.1016/S2352-4642(24)00233-5_bib10) 2021; 96 Lee (10.1016/S2352-4642(24)00233-5_bib25) 2022; 98 Chabrier (10.1016/S2352-4642(24)00233-5_bib11) 2021; 52 Ganesan (10.1016/S2352-4642(24)00233-5_bib2) 2003; 53 van Horn (10.1016/S2352-4642(24)00233-5_bib28) 2021; 31 Stracke (10.1016/S2352-4642(24)00233-5_bib26) 2022; 12 Fullerton (10.1016/S2352-4642(24)00233-5_bib3) 2002; 59 Rivkin (10.1016/S2352-4642(24)00233-5_bib5) 2015; 46 Kossorotoff (10.1016/S2352-4642(24)00233-5_bib12) 2022; 5 Bhatia (10.1016/S2352-4642(24)00233-5_bib7) 2019; 24 Harrar (10.1016/S2352-4642(24)00233-5_bib17) 2020; 216 Bernard (10.1016/S2352-4642(24)00233-5_bib20) 2012; 43 Sporns (10.1016/S2352-4642(24)00233-5_bib27) 2019; 8 Bendszus (10.1016/S2352-4642(24)00233-5_bib23) 2023; 402 Bhatia (10.1016/S2352-4642(24)00233-5_bib15) 2022; 79 Sporns (10.1016/S2352-4642(24)00233-5_bib22) 2021; 14 Goyal (10.1016/S2352-4642(24)00233-5_bib6) 2016; 387 Lagman-Bartolome (10.1016/S2352-4642(24)00233-5_bib19) 2013; 55 Majoie (10.1016/S2352-4642(24)00233-5_bib29) 2023; 402 Sporns (10.1016/S2352-4642(24)00233-5_bib8) 2020; 77 deVeber (10.1016/S2352-4642(24)00233-5_bib18) 2010; 6 Sporns (10.1016/S2352-4642(24)00233-5_bib13) 2021; 12 Tan (10.1016/S2352-4642(24)00233-5_bib30) 2024; 9 Böhmer (10.1016/S2352-4642(24)00233-5_bib21) 2019; 50 Wittenberg (10.1016/S2352-4642(24)00233-5_bib24) 2009; 51 39401506 - Lancet Child Adolesc Health. 2024 Dec;8(12):844-845. doi: 10.1016/S2352-4642(24)00257-8. |
| References_xml | – volume: 46 start-page: 880 year: 2015 end-page: 885 ident: bib5 article-title: Thrombolysis in pediatric stroke study publication-title: Stroke – volume: 55 start-page: 434 year: 2013 end-page: 439 ident: bib19 article-title: Basilar artery strokes in children: good outcomes with conservative medical treatment publication-title: Dev Med Child Neurol – volume: 9 start-page: 126 year: 2024 end-page: 133 ident: bib30 article-title: Thrombus migration in patients with acute ischaemic stroke undergoing endovascular thrombectomy publication-title: Stroke Vasc Neurol – volume: 96 start-page: e343 year: 2021 end-page: e351 ident: bib10 article-title: Clinical diffusion mismatch to select pediatric patients for embolectomy 6 to 24 hours after stroke: an analysis of the Save ChildS study publication-title: Neurology – volume: 77 start-page: 25 year: 2020 end-page: 34 ident: bib8 article-title: Feasibility, safety, and outcome of endovascular recanalization in childhood stroke: the Save ChildS study publication-title: JAMA Neurol – volume: 45 start-page: 177 year: 2015 end-page: 189 ident: bib4 article-title: Stroke Prevalence, mortality and disability-adjusted life years in children and youth aged 0–19 years: data from the Global and Regional Burden of Stroke 2013 publication-title: Neuroepidemiology – volume: 402 start-page: 965 year: 2023 end-page: 974 ident: bib29 article-title: Value of intravenous thrombolysis in endovascular treatment for large-vessel anterior circulation stroke: individual participant data meta-analysis of six randomised trials publication-title: Lancet – volume: 80 start-page: 910 year: 2023 end-page: 918 ident: bib16 article-title: Association between thrombectomy and functional outcomes in pediatric patients with acute ischemic stroke from large vessel occlusion publication-title: JAMA Neurol – volume: 12 year: 2022 ident: bib26 article-title: Case report: successful mechanical thrombectomy in a newborn with basilar artery occlusion publication-title: Front Neurol – volume: 53 start-page: 167 year: 2003 end-page: 173 ident: bib2 article-title: Investigation of risk factors in children with arterial ischemic stroke publication-title: Ann Neurol – volume: 59 start-page: 34 year: 2002 end-page: 39 ident: bib3 article-title: Deaths from stroke in US children, 1979 to 1998 publication-title: Neurology – volume: 51 start-page: 1182 year: 2020 end-page: 1189 ident: bib9 article-title: Does device selection impact recanalization rate and neurological outcome? An analysis of the Save ChildS study publication-title: Stroke – volume: 79 start-page: 488 year: 2022 end-page: 497 ident: bib15 article-title: Incidence and natural history of pediatric large vessel occlusion stroke: a population study publication-title: JAMA Neurol – volume: 6 start-page: 64 year: 2010 end-page: 66 ident: bib18 article-title: Delays in the timely diagnosis of stroke in children publication-title: Nat Rev Neurol – volume: 43 start-page: 371 year: 2012 end-page: 377 ident: bib20 article-title: Towards a consensus-based classification of childhood arterial ischemic stroke publication-title: Stroke – volume: 50 start-page: 83 year: 2019 end-page: 87 ident: bib21 article-title: Impact of Childhood Arterial Ischemic Stroke Standardized Classification and Diagnostic Evaluation classification on further course of arteriopathy and recurrence of childhood stroke publication-title: Stroke – volume: 98 start-page: e352 year: 2022 end-page: e363 ident: bib25 article-title: Cerebrovascular collateral integrity in pediatric large vessel occlusion: analysis of the Save ChildS study publication-title: Neurology – volume: 24 start-page: 558 year: 2019 end-page: 571 ident: bib7 article-title: Mechanical thrombectomy in pediatric stroke: systematic review, individual patient data meta-analysis, and case series publication-title: J Neurosurg Pediatr – volume: 31 start-page: 1093 year: 2021 end-page: 1100 ident: bib28 article-title: ASPECTS interobserver agreement of 100 investigators from the TENSION study publication-title: Clin Neuroradiol – volume: 216 start-page: 136 year: 2020 end-page: 141 ident: bib17 article-title: A stroke alert protocol decreases the time to diagnosis of brain attack symptoms in a pediatric emergency department publication-title: J Pediatr – volume: 141 start-page: 118 year: 2023 end-page: 132 ident: bib31 article-title: Consensus-based evaluation of outcome measures in pediatric stroke care: a toolkit publication-title: Pediatr Neurol – volume: 51 start-page: 130 year: 2009 end-page: 133 ident: bib24 article-title: Neural plasticity and treatment across the lifespan for motor deficits in cerebral palsy publication-title: Dev Med Child Neurol – volume: 8 start-page: 12 year: 2022 ident: bib1 article-title: Childhood stroke publication-title: Nat Rev Dis Primers – volume: 378 start-page: 11 year: 2018 end-page: 21 ident: bib32 article-title: Thrombectomy 6 to 24 hours after stroke with a mismatch between deficit and infarct publication-title: N Engl J Med – volume: 12 year: 2021 ident: bib13 article-title: A prospective multicenter registry on feasibility, safety, and outcome of endovascular recanalization in childhood stroke (Save ChildS Pro) publication-title: Front Neurol – volume: 14 year: 2021 ident: bib22 article-title: Expanding indications for endovascular thrombectomy—how to leave no patient behind publication-title: Ther Adv Neurol Disord – volume: 387 start-page: 1723 year: 2016 end-page: 1731 ident: bib6 article-title: Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials publication-title: Lancet – volume: 52 start-page: 381 year: 2021 end-page: 384 ident: bib11 article-title: Hyperacute recanalization strategies and childhood stroke in the evidence age publication-title: Stroke – volume: 5 year: 2022 ident: bib12 article-title: Recanalization treatments for pediatric acute ischemic stroke in France publication-title: JAMA Netw Open – volume: 5 start-page: 825 year: 2021 end-page: 836 ident: bib14 article-title: Current treatment for childhood arterial ischaemic stroke publication-title: Lancet Child Adolesc Health – volume: 402 start-page: 1753 year: 2023 end-page: 1763 ident: bib23 article-title: Endovascular thrombectomy for acute ischaemic stroke with established large infarct: multicentre, open-label, randomised trial publication-title: Lancet – volume: 53 start-page: 167 year: 2003 ident: 10.1016/S2352-4642(24)00233-5_bib2 article-title: Investigation of risk factors in children with arterial ischemic stroke publication-title: Ann Neurol doi: 10.1002/ana.10423 – volume: 5 start-page: 825 year: 2021 ident: 10.1016/S2352-4642(24)00233-5_bib14 article-title: Current treatment for childhood arterial ischaemic stroke publication-title: Lancet Child Adolesc Health doi: 10.1016/S2352-4642(21)00167-X – volume: 8 year: 2019 ident: 10.1016/S2352-4642(24)00233-5_bib27 article-title: Thrombectomy in childhood stroke publication-title: J Am Heart Assoc doi: 10.1161/JAHA.118.011335 – volume: 8 start-page: 12 year: 2022 ident: 10.1016/S2352-4642(24)00233-5_bib1 article-title: Childhood stroke publication-title: Nat Rev Dis Primers doi: 10.1038/s41572-022-00337-x – volume: 12 year: 2021 ident: 10.1016/S2352-4642(24)00233-5_bib13 article-title: A prospective multicenter registry on feasibility, safety, and outcome of endovascular recanalization in childhood stroke (Save ChildS Pro) publication-title: Front Neurol doi: 10.3389/fneur.2021.736092 – volume: 45 start-page: 177 year: 2015 ident: 10.1016/S2352-4642(24)00233-5_bib4 article-title: Stroke Prevalence, mortality and disability-adjusted life years in children and youth aged 0–19 years: data from the Global and Regional Burden of Stroke 2013 publication-title: Neuroepidemiology doi: 10.1159/000441087 – volume: 96 start-page: e343 year: 2021 ident: 10.1016/S2352-4642(24)00233-5_bib10 article-title: Clinical diffusion mismatch to select pediatric patients for embolectomy 6 to 24 hours after stroke: an analysis of the Save ChildS study publication-title: Neurology doi: 10.1212/WNL.0000000000011107 – volume: 55 start-page: 434 year: 2013 ident: 10.1016/S2352-4642(24)00233-5_bib19 article-title: Basilar artery strokes in children: good outcomes with conservative medical treatment publication-title: Dev Med Child Neurol doi: 10.1111/dmcn.12092 – volume: 59 start-page: 34 year: 2002 ident: 10.1016/S2352-4642(24)00233-5_bib3 article-title: Deaths from stroke in US children, 1979 to 1998 publication-title: Neurology doi: 10.1212/WNL.59.1.34 – volume: 98 start-page: e352 year: 2022 ident: 10.1016/S2352-4642(24)00233-5_bib25 article-title: Cerebrovascular collateral integrity in pediatric large vessel occlusion: analysis of the Save ChildS study publication-title: Neurology doi: 10.1212/WNL.0000000000013081 – volume: 24 start-page: 558 year: 2019 ident: 10.1016/S2352-4642(24)00233-5_bib7 article-title: Mechanical thrombectomy in pediatric stroke: systematic review, individual patient data meta-analysis, and case series publication-title: J Neurosurg Pediatr doi: 10.3171/2019.5.PEDS19126 – volume: 50 start-page: 83 year: 2019 ident: 10.1016/S2352-4642(24)00233-5_bib21 article-title: Impact of Childhood Arterial Ischemic Stroke Standardized Classification and Diagnostic Evaluation classification on further course of arteriopathy and recurrence of childhood stroke publication-title: Stroke doi: 10.1161/STROKEAHA.118.023060 – volume: 387 start-page: 1723 year: 2016 ident: 10.1016/S2352-4642(24)00233-5_bib6 article-title: Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials publication-title: Lancet doi: 10.1016/S0140-6736(16)00163-X – volume: 6 start-page: 64 year: 2010 ident: 10.1016/S2352-4642(24)00233-5_bib18 article-title: Delays in the timely diagnosis of stroke in children publication-title: Nat Rev Neurol doi: 10.1038/nrneurol.2009.228 – volume: 80 start-page: 910 year: 2023 ident: 10.1016/S2352-4642(24)00233-5_bib16 article-title: Association between thrombectomy and functional outcomes in pediatric patients with acute ischemic stroke from large vessel occlusion publication-title: JAMA Neurol doi: 10.1001/jamaneurol.2023.2303 – volume: 402 start-page: 1753 year: 2023 ident: 10.1016/S2352-4642(24)00233-5_bib23 article-title: Endovascular thrombectomy for acute ischaemic stroke with established large infarct: multicentre, open-label, randomised trial publication-title: Lancet doi: 10.1016/S0140-6736(23)02032-9 – volume: 51 start-page: 1182 year: 2020 ident: 10.1016/S2352-4642(24)00233-5_bib9 article-title: Does device selection impact recanalization rate and neurological outcome? An analysis of the Save ChildS study publication-title: Stroke doi: 10.1161/STROKEAHA.119.028221 – volume: 5 year: 2022 ident: 10.1016/S2352-4642(24)00233-5_bib12 article-title: Recanalization treatments for pediatric acute ischemic stroke in France publication-title: JAMA Netw Open doi: 10.1001/jamanetworkopen.2022.31343 – volume: 12 year: 2022 ident: 10.1016/S2352-4642(24)00233-5_bib26 article-title: Case report: successful mechanical thrombectomy in a newborn with basilar artery occlusion publication-title: Front Neurol doi: 10.3389/fneur.2021.790486 – volume: 52 start-page: 381 year: 2021 ident: 10.1016/S2352-4642(24)00233-5_bib11 article-title: Hyperacute recanalization strategies and childhood stroke in the evidence age publication-title: Stroke doi: 10.1161/STROKEAHA.120.031133 – volume: 46 start-page: 880 year: 2015 ident: 10.1016/S2352-4642(24)00233-5_bib5 article-title: Thrombolysis in pediatric stroke study publication-title: Stroke doi: 10.1161/STROKEAHA.114.008210 – volume: 79 start-page: 488 year: 2022 ident: 10.1016/S2352-4642(24)00233-5_bib15 article-title: Incidence and natural history of pediatric large vessel occlusion stroke: a population study publication-title: JAMA Neurol doi: 10.1001/jamaneurol.2022.0323 – volume: 14 year: 2021 ident: 10.1016/S2352-4642(24)00233-5_bib22 article-title: Expanding indications for endovascular thrombectomy—how to leave no patient behind publication-title: Ther Adv Neurol Disord doi: 10.1177/1756286421998905 – volume: 378 start-page: 11 year: 2018 ident: 10.1016/S2352-4642(24)00233-5_bib32 article-title: Thrombectomy 6 to 24 hours after stroke with a mismatch between deficit and infarct publication-title: N Engl J Med doi: 10.1056/NEJMoa1706442 – volume: 43 start-page: 371 year: 2012 ident: 10.1016/S2352-4642(24)00233-5_bib20 article-title: Towards a consensus-based classification of childhood arterial ischemic stroke publication-title: Stroke doi: 10.1161/STROKEAHA.111.624585 – volume: 31 start-page: 1093 year: 2021 ident: 10.1016/S2352-4642(24)00233-5_bib28 article-title: ASPECTS interobserver agreement of 100 investigators from the TENSION study publication-title: Clin Neuroradiol doi: 10.1007/s00062-020-00988-x – volume: 51 start-page: 130 issue: suppl 4 year: 2009 ident: 10.1016/S2352-4642(24)00233-5_bib24 article-title: Neural plasticity and treatment across the lifespan for motor deficits in cerebral palsy publication-title: Dev Med Child Neurol doi: 10.1111/j.1469-8749.2009.03425.x – volume: 141 start-page: 118 year: 2023 ident: 10.1016/S2352-4642(24)00233-5_bib31 article-title: Consensus-based evaluation of outcome measures in pediatric stroke care: a toolkit publication-title: Pediatr Neurol doi: 10.1016/j.pediatrneurol.2023.01.009 – volume: 402 start-page: 965 year: 2023 ident: 10.1016/S2352-4642(24)00233-5_bib29 article-title: Value of intravenous thrombolysis in endovascular treatment for large-vessel anterior circulation stroke: individual participant data meta-analysis of six randomised trials publication-title: Lancet doi: 10.1016/S0140-6736(23)01142-X – volume: 77 start-page: 25 year: 2020 ident: 10.1016/S2352-4642(24)00233-5_bib8 article-title: Feasibility, safety, and outcome of endovascular recanalization in childhood stroke: the Save ChildS study publication-title: JAMA Neurol doi: 10.1001/jamaneurol.2019.3403 – volume: 9 start-page: 126 year: 2024 ident: 10.1016/S2352-4642(24)00233-5_bib30 article-title: Thrombus migration in patients with acute ischaemic stroke undergoing endovascular thrombectomy publication-title: Stroke Vasc Neurol doi: 10.1136/svn-2022-002257 – volume: 216 start-page: 136 year: 2020 ident: 10.1016/S2352-4642(24)00233-5_bib17 article-title: A stroke alert protocol decreases the time to diagnosis of brain attack symptoms in a pediatric emergency department publication-title: J Pediatr doi: 10.1016/j.jpeds.2019.09.027 – reference: 39401506 - Lancet Child Adolesc Health. 2024 Dec;8(12):844-845. doi: 10.1016/S2352-4642(24)00257-8. |
| SSID | ssj0001881704 |
| Score | 2.3266494 |
| Snippet | Emerging evidence suggests that endovascular thrombectomy is beneficial for treatment of childhood stroke, but the safety and effectiveness of endovascular... |
| SourceID | proquest pubmed crossref elsevier |
| SourceType | Aggregation Database Index Database Enrichment Source Publisher |
| StartPage | 882 |
| SubjectTerms | Adolescent Child Child, Preschool Endovascular Procedures - methods Female Humans Infant Infant, Newborn Ischemic Stroke - surgery Ischemic Stroke - therapy Male Prospective Studies Registries Stroke - surgery Stroke - therapy Thrombectomy - methods Treatment Outcome |
| Title | Endovascular thrombectomy for childhood stroke (Save ChildS Pro): an international, multicentre, prospective registry study |
| URI | https://dx.doi.org/10.1016/S2352-4642(24)00233-5 https://www.ncbi.nlm.nih.gov/pubmed/39401507 https://www.proquest.com/docview/3116675508 |
| Volume | 8 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Jb9QwFLaGqYS4IHbKJiOB1IqmTBxn4zagooqqHJhB9GZ5i6BLgmYyl-E38R95thM7BapCL9Eo8hL5fWN_7_ktCL3IEymooJOI5DEoKJrmkYhLFQE1kECQC02sonj4Mdv_TD8cpUej0c-B19KqFbty_de4kqtIFd6BXE2U7H9I1g8KL-A3yBeeIGF4_pOM92oVXElNwYMzYYzwZ84JU_qsxct20ZxYMjkzxYZsOuOZiRF4SUob7VzbtBHeMmjW3XoaWtdNa_KEjbYPynxlijmYGnGD3LTHAXSnNqrazW6BFZJGdVGX4ca-WTgab72EQwHot1_hQ_pYtfabDyaaisVqvbbG3XmjVLj-EsvOwLDkQzMGob-5hPj4muDMBFsgAXoY0Yye26-LISzJYPMtXBmj_hx3ZUj_OCKctWLmh4a1JxSW27CXJErDuei9FW1b09T420Kj9BraIKCVkDHamB58-nIQjHqFyXdIbUHDbvgQNfY6zLlF6HY330V86CJ9x_Ke-S10s1NY8NSh7zYa6foOun7YuWTcRT-GIMRDEGIAIfYgxA6EeMtAEDsIYoDg9hvMa3wOfjt4AL4dPIAe7qGHLfTuofn7vfm7_air6BFJGpM2iiudVlmZJERQXRW5VIIIk0IuF1yUqcomfCJjrkrQG7jOTK2znE8q4NRA5WSe3Efjuqn1Q4RjSbQQUossK6iStKSq4lRyntBK5UW6iWi_rEx22e5N0ZVT5t0ajTSYkQYjlFlpMOi267t9d-leLutQ9DJjHWd1XJQB3i7r-ryXMYM93VzU8Vo3qyVL4jgDRR50p030wAnff01SUmOkzB9dfeLH6Eb4Bz5B43ax0k-BWrfiWQfoX6MRymc |
| linkProvider | Library Specific Holdings |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Endovascular+thrombectomy+for+childhood+stroke+%28Save+ChildS+Pro%29%3A+an+international%2C+multicentre%2C+prospective+registry+study&rft.jtitle=The+lancet+child+%26+adolescent+health&rft.au=Sporns%2C+Peter+B&rft.au=Bhatia%2C+Kartik&rft.au=Abruzzo%2C+Todd&rft.au=Pabst%2C+Lisa&rft.date=2024-12-01&rft.pub=Elsevier+Ltd&rft.issn=2352-4642&rft.volume=8&rft.issue=12&rft.spage=882&rft.epage=890&rft_id=info:doi/10.1016%2FS2352-4642%2824%2900233-5&rft.externalDocID=S2352464224002335 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=2352-4642&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=2352-4642&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=2352-4642&client=summon |