Interruption of β-Catenin Signaling Reduces Neurogenesis in Alzheimer's Disease - He, Ping; Shen, Yong (The Journal of neuroscience, 2009)
Keywords: Adult Stem Cells - physiology; Age Factors; Aged, 80 and over; Alzheimer Disease - pathology; Alzheimer Disease - physiopathology; Amyloid beta-Peptides - metabolism; Amyloid beta-Peptides - pharmacology; Amyloid beta-Protein Precursor - genetics; Animals; Apoptosis - drug effects; beta Catenin - metabolism; Cells, Cultured; Cerebral Cortex - pathology; Cerebral Cortex - physiopathology; Chondroitin Sulfate Proteoglycans - metabolism; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay - methods; Female; Gene Expression Regulation - physiology; Glycogen Synthase Kinase 3 - genetics; Glycogen Synthase Kinase 3 - metabolism; Glycogen Synthase Kinase 3 beta; Humans; In Situ Nick-End Labeling - methods; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutant Proteins - genetics; Nerve Tissue Proteins - metabolism; Neural Cell Adhesion Molecule L1 - metabolism; Neurogenesis - physiology; Neuroglia - drug effects; Neuroglia - metabolism; Neuroglia - pathology; O Antigens - metabolism; Peptide Fragments - metabolism; Peptide Fragments - pharmacology; RNA, Small Interfering - metabolism; Sialic Acids - metabolism; Signal Transduction - physiology; Transfection - methods