TOMM40 Genetic Variants Cause Neuroinflammation in Alzheimer’s Disease - Chen, Yi-Chun; Chang, Shih-Cheng; Lee, Yun-Shien; Ho, Wei-Min; Huang, Yu-Hua; Wu, Yah-Yuan; Chu, Yi-Chuan; Wu, Kuan-Hsuan; Wei, Li-Shan; Wang, Hung-Li; Chiu, Ching-Chi (International journal of molecular sciences, 2023)
Keywords: Alzheimer Disease - genetics; Alzheimer Disease - pathology; Alzheimer's disease; Apoptosis; Biobanks; Cytokines; Genes; Genetic Variation; Genomes; Humans; Hypotheses; Inflammasomes - metabolism; Interleukin-6 - metabolism; Kinases; Microglia - metabolism; Mitochondria; Mitochondrial Precursor Protein Import Complex Proteins - genetics; Mutation; Neuroinflammatory Diseases - genetics; NLR Family, Pyrin Domain-Containing 3 Protein - metabolism; Oxidative stress; Pathogenesis; Protein expression; Proteins; Tumor necrosis factor-TNF; Taiwan; NF-κB; TOMM40; Alzheimer’s disease; SNP; neuroinflammation; NLRP3; microglia; hippocampal neurons