Inferring recombination patterns in African populations

• Published in: Human molecular genetics Vol. 30; no. R1; pp. R11 - R16
• Main Authors: van Eeden, Gerald, Uren, Caitlin, Möller, Marlo, Henn, Brenna M
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 26.04.2021
• Subjects: Africa; Blacks - genetics; Decision Trees; Evolution, Molecular; Genome-Wide Association Study; Genomics - methods; Haplotypes; Humans; Invited Review; Polymorphism, Single Nucleotide; Recombination, Genetic; Africa

Abstract Although several high-resolution recombination maps exist for European-descent populations, the recombination landscape of African populations remains relatively understudied. Given that there is high genetic divergence among groups in Africa, it is possible that recombination hotspots also...