Trapping endoplasmic reticulum with amphiphilic AIE-active sensor via specific interaction of ATP-sensitive potassium (KATP)

• Published in: National science review Vol. 8; no. 6; p. nwaa198
• Main Authors: Zhu, Zhirong, Wang, Qi, Liao, Hongze, Liu, Ming, Liu, Zhenxing, Zhang, Youheng, Zhu, Wei-Hong
• Format: Journal Article
• Language: English
• Published: China Oxford University Press 01.06.2021
• Subjects: CHEMISTRY; aggregation-induced emission; targeting specificity; AIEgens; high-fidelity tracking; endoplasmic reticulum; amphiphilic AIEgens

Abstract The current aggregation-induced emission luminogens (AIEgens) sometimes suffer from poor targeting selectivity due to undesirable aggregation in the hydrophilic biosystem with ‘always-on’ fluorescence or unspecific aggregation in the lipophilic organelle with prematurely activated fluoresce...