The Role of Integrin α6 (CD49f) in Stem Cells: More than a Conserved Biomarker

• Published in: Stem cells and development Vol. 26; no. 15; p. 1090
• Main Authors: Krebsbach, Paul H, Villa-Diaz, Luis G
• Format: Journal Article
• Language: English
• Published: United States 01.08.2017
• Subjects: Animals; Biomarkers - metabolism; Cell Self Renewal; Germ Cells - metabolism; Humans; Integrin alpha6 - metabolism; Protein Binding; Stem Cells - metabolism; stem cells; niche; differentiation; self-renewal; integrin α6; CD49f

Stem cells have the capacity for self-renewal and differentiation into specialized cells that form and repopulated all tissues and organs, from conception to adult life. Depending on their capacity for differentiation, stem cells are classified as totipotent (ie, zygote), pluripotent (ie, embryonic...