Fetal heart rate responses in chronic hypoxaemia with superimposed repeated hypoxaemia consistent with early labour: a controlled study in fetal sheep

• Published in: BJOG : an international journal of obstetrics and gynaecology Vol. 130; no. 8; pp. 881 - 890
• Main Authors: Lear, C. A., Georgieva, A., Beacom, M. J., Wassink, G., Dhillon, S. K., Lear, B. A., Mills, O. J., Westgate, J. A., Bennet, L., Gunn, A. J.
• Format: Journal Article
• Language: English
• Published: England Wiley Subscription Services, Inc 01.07.2023
• Subjects: Acidosis - etiology; Animals; asphyxia; Blood pressure; cardiotocography; computerised fetal heart rate monitoring; deceleration area; deceleration capacity; Female; Fetus; Fetuses; Heart rate; Heart Rate, Fetal - physiology; Humans; Hypotension; Hypotension - complications; Hypoxia - complications; hypoxia‐ischaemia; mortality; peripheral chemoreflex; phase rectified signal averaging; Pregnancy; Prospective Studies; Risk factors; Sheep; stillbirth; Umbilical cord; Umbilical Cord - blood supply; hypotension; hypoxia-ischaemia; phase rectified signal averaging; peripheral chemoreflex; mortality; stillbirth; deceleration capacity; computerised fetal heart rate monitoring; asphyxia; cardiotocography; deceleration area

Objective Deceleration area (DA) and capacity (DC) of the fetal heart rate can help predict risk of intrapartum fetal compromise. However, their predictive value in higher risk pregnancies is unclear. We investigated whether they can predict the onset of hypotension during brief hypoxaemia repeated...