Meta‐analysis: Interleukin 6 gene ‐174G/C polymorphism associated with type 2 diabetes mellitus and interleukin 6 changes

• Published in: Journal of cellular and molecular medicine Vol. 25; no. 12; pp. 5628 - 5639
• Main Authors: Cheng, Hao, Zhu, Wenbin, Zhu, Mou, Sun, Yan, Sun, Xiaojie, Jia, Di, Yang, Chao, Yu, Haitao, Zhang, Chunjing
• Format: Journal Article
• Language: English
• Published: England John Wiley & Sons, Inc 01.06.2021; John Wiley and Sons Inc
• Subjects: Bias; Cholesterol; Cytokines; Diabetes; Diabetes mellitus (non-insulin dependent); Ethnicity; Gene polymorphism; Glucose; Health care; Hospitals; Interleukin 6; Meta-analysis; Original; Phenotypes; Polymorphism; risk; type 2 diabetes mellitus; Greece; Turkey; United States > US; China; Poland; Kuwait; India; type 2 diabetes mellitus; interleukin 6; polymorphism; risk
• ISSN: 1582-1838; 1582-4934; 1582-4934
• DOI: 10.1111/jcmm.16575

The gene coding interleukin 6 (IL‐6) is a promising candidate in predisposition to type 2 diabetes mellitus (T2DM). This study aimed to meta‐analytically examine the association of IL‐6 gene −174G/C polymorphism with T2DM and circulating IL‐6 changes across −174G/C genotypes. Odds ratio (OR) and sta...