Vitamin D derivatives induce apoptosis and downregulate ICAM-1 levels in peripheral blood mononuclear cells of inflammatory bowel disease patients - Martinesi, Maria; Treves, Cristina; d'Albasio, Giuseppe; Bagnoli, Siro; Bonanomi, Andrea G.; Stio, Maria (Inflammatory bowel diseases, 2008)
Keywords: 1,25‐dihydroxyvitamin D3; adhesion molecules; Adult; Aged; Apoptosis; Apoptosis - drug effects; Apoptosis - genetics; Blotting, Western; Calcitriol; Calcitriol - analogs & derivatives; Calcitriol - therapeutic use; Caspase-3; Cell adhesion molecules; Cell interactions; Cell Proliferation - drug effects; Cells, Cultured; DNA - genetics; DNA Fragmentation; Down-Regulation - genetics; Drug development; EB1089; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunosuppressive Agents - therapeutic use; Inflammatory bowel disease; Inflammatory bowel diseases; Inflammatory Bowel Diseases - blood; Inflammatory Bowel Diseases - drug therapy; Inflammatory Bowel Diseases - genetics; infliximab; intercellular adhesion molecule 1; Intercellular Adhesion Molecule-1 - biosynthesis; Intercellular Adhesion Molecule-1 - drug effects; Intercellular Adhesion Molecule-1 - genetics; Intestine; Leukocyte migration; Leukocytes, Mononuclear - metabolism; Lipopolysaccharides; Lymphocytes; Male; Middle Aged; Monoclonal antibodies; Peripheral blood mononuclear cells; Poly(ADP-ribose) polymerase; Prognosis; Tumor necrosis factor- alpha; Vitamin D; Vitamin D - administration & dosage; Vitamin D - agonists; Vitamin D - analogs & derivatives; Vitamin D - therapeutic use; Vitamins - therapeutic use; Western blotting; apoptosis; EB1089; 1,25-dihydroxyvitamin D; adhesion molecules; infliximab; inflammatory bowel disease