Pharmacokinetic–Pharmacodynamic Cutoff Values for Doxycycline in Pigs to Support the Establishment of Clinical Breakpoints for Antimicrobial Susceptibility Testing - Toutain, Pierre‐Louis; Bousquet‐Melou, Alain; Ferran, Aude A.; Roques, Béatrice B.; Castillo, Jérôme R. E.; Lees, Peter; Croubels, Siska; Bousquet, Eric; Pelligand, Ludovic (Journal of veterinary pharmacology and therapeutics, 2025)
Keywords: Animals; Anti-Bacterial Agents - administration & dosage; Anti-Bacterial Agents - blood; Anti-Bacterial Agents - pharmacokinetics; Anti-Bacterial Agents - pharmacology; Antimicrobial susceptibility testing; Biological Availability; doxycycline; Doxycycline - administration & dosage; Doxycycline - blood; Doxycycline - pharmacokinetics; Doxycycline - pharmacology; Half-Life; Life Sciences; Microbial Sensitivity Tests - veterinary; Models, Biological; Original; Pharmaceutical sciences; pharmacokinetics; Pharmacology; pigs; PK/PD cutoff; Swine - blood; Swine - metabolism; Antimicrobial susceptibility testing; pharmacokinetics; pigs; doxycycline; PK/PD cutoff