Synthesis and anti-inflammatory activities of novel dihydropyranoaurone derivatives - Wang, Zheng; Bae, Eun Ju; Han, Young Taek (Archives of pharmacal research, 2017)
Keywords: aldehydes; Animals; anti-inflammatory activity; anti-inflammatory agents; Anti-Inflammatory Agents, Non-Steroidal - chemical synthesis; Anti-Inflammatory Agents, Non-Steroidal - chemistry; Anti-Inflammatory Agents, Non-Steroidal - pharmacology; aurones; Benzofurans - chemical synthesis; Benzofurans - chemistry; Benzofurans - pharmacology; Cell Survival - drug effects; derivatization; Dose-Response Relationship, Drug; Enzyme Inhibitors - chemical synthesis; Enzyme Inhibitors - chemistry; Enzyme Inhibitors - pharmacology; Humans; inducible nitric oxide synthase; Lipopolysaccharides - antagonists & inhibitors; Lipopolysaccharides - pharmacology; Macrophages - drug effects; Macrophages - metabolism; Medicine; Mice; Molecular Structure; Nitric Oxide Synthase Type II - antagonists & inhibitors; Nitric Oxide Synthase Type II - metabolism; nitrites; Nitrites - antagonists & inhibitors; Nitrites - metabolism; Pharmacology/Toxicology; Pharmacy; RAW 264.7 Cells; Research Article; Structure-Activity Relationship; structure-activity relationships; 약학; Late-stage derivatization; Aldol reaction; Synthesis; Dihydropyranoaurone; Nitric oxide; Anti-inflammation