A prospective longitudinal study evaluating a T-cell-based assay for latent tuberculosis infection in health-care workers in a general hospital in Beijing

• Published in: Chinese medical journal Vol. 126; no. 11; pp. 2039 - 2044
• Main Authors: ZHANG, Li-fan, LIU, Xiao-qing, ZHANG, Yao, DENG, Guo-hua, Pareek, Manish, Lalvani, Ajit
• Format: Journal Article
• Language: English
• Published: China Clinical Epidemiology Unit,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences & Peking Union Medical College,Beijing 100730,China%Department of Infectious Diseases ,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences & Peking Union Medical College,Beijing 100730,China%Tuberculosis Research Unit,Department of Respiratory Medicine,National Heart and Lung Institute,Imperial College London,St Mary's Campus,Norfolk Place,London,W21PG,United Kingdom 05.06.2013; Department of Infectious Diseases ,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences & Peking Union Medical College,Beijing 100730,China
• Subjects: Adult; Female; Health Personnel; Hospitals, General; Humans; Latent Tuberculosis - diagnosis; Latent Tuberculosis - etiology; Latent Tuberculosis - immunology; Longitudinal Studies; Male; Pilot Projects; Prospective Studies; Risk Factors; Tuberculin Test; latent tuberculosis infection; T-SPOT.TB; exposure; tuberculin skin test; follow-up study

The health-care workers (HCWs) are at high risk of acquiring infection with Mycobacterium tuberculosis. The objectives of this study were to compare the performance of the T-SPOT.TB and tuberculin skin test (TST) for latent tuberculosis infection (LTBI), evaluate diagnostic concordance and risk fact...