Hemodynamic Effects of Combination Therapy With Inhaled Nitric Oxide and Iloprost in Patients With Pulmonary Hypertension and Right Ventricular Dysfunction After High-Risk Cardiac Surgery

• Published in: Journal of cardiothoracic and vascular anesthesia Vol. 27; no. 3; pp. 459 - 466
• Main Authors: Antoniou, Theofani, MD, PhD, Koletsis, Efstratios N., MD, PhD, Prokakis, Christos, MD, PhD, Rellia, Panagiota, MD, Thanopoulos, Apostolos, MD, Theodoraki, Kassiani, MD, PhD, Zarkalis, Dimitrios, MD, Sfyrakis, Petros, MD
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.06.2013
• Subjects: Aerosols; Aged; Anesthesia & Perioperative Care; Arterial Pressure - physiology; Cardiac Surgical Procedures - methods; Critical Care; Electrocardiography; Extracorporeal Circulation; Female; Heart Valves - surgery; Hemodynamics - drug effects; Humans; Hypertension, Pulmonary - drug therapy; Hypertension, Pulmonary - physiopathology; iloprost; Iloprost - administration & dosage; Iloprost - therapeutic use; inhaled nitric oxide; Male; Middle Aged; Nitric Oxide - administration & dosage; Nitric Oxide - therapeutic use; pulmonary hypertension; right ventricular dysfunction; Risk; Treatment Outcome; tricuspid annular plane systolic excursion; tricuspid annular velocity; Vascular Resistance - physiology; Vasodilator Agents - administration & dosage; Vasodilator Agents - therapeutic use; Ventricular Dysfunction, Right - drug therapy; Ventricular Dysfunction, Right - physiopathology; tricuspid annular velocity; tricuspid annular plane systolic excursion; right ventricular dysfunction; inhaled nitric oxide; iloprost; pulmonary hypertension

Objective The purpose of this study was to evaluate the hemodynamic effects of inhaled nitric oxide (NO) plus aerosolized iloprost in patients with pulmonary hypertension/right ventricular dysfunction after cardiac surgery. Design A retrospective study. Setting A single center. Participants Eight co...