High discordance rates between sub-areolar and peri-tumoural breast lymphoscintigraphy
Abstract Objective To test the hypothesis that sub-areolar (SA) lymphoscintigraphy (LSG) identifies the same sentinel node as peri-tumoural (PT) injections. Background It is commonly believed that all LSG techniques will identify the same sentinel lymph nodes (SLN) draining the breast. Hybrid imagin...
Saved in:
Published in | European journal of surgical oncology Vol. 39; no. 10; pp. 1053 - 1060 |
---|---|
Main Authors | , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
England
Elsevier Ltd
01.10.2013
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | Abstract Objective To test the hypothesis that sub-areolar (SA) lymphoscintigraphy (LSG) identifies the same sentinel node as peri-tumoural (PT) injections. Background It is commonly believed that all LSG techniques will identify the same sentinel lymph nodes (SLN) draining the breast. Hybrid imaging technology (SPECT/CT) allows accurate identification of the exact location of SLNs. Using SPECT/CT SA and PT LSG techniques were compared. Method In a multi-centre trial 39 patients sequentially underwent LSG (SA followed by PT) separated by 2–7 days. Patients were referred by 4 surgeons to 3 LSG centres, with standardization of isotope (99mTc-antimony sulfide colloid), LSG and SPECT/CT evaluation techniques. LSG were evaluated for SLN concordance and degree of discordance in the axilla and internal mammary nodes (IMN). Results 39 eligible patients, median age 62 years, were recruited. Successful axillary SLN mapping for SA and PT injection techniques was 87% and 95% respectively. Successful internal mammary SLN mapping occurred with SA and PT LSG in 5% and 36% respectively. Discordance was identified in the IMN (39%) and axilla (21%), with an overall rate of discordance between SA and PT LSG of 56%. Conclusions There is a high level of discordance in the localization of SLN by these commonly used LSG injection techniques. This discordance has implications for accuracy of axillary and extra-axillary staging and could impact on patient outcome. |
---|---|
AbstractList | To test the hypothesis that sub-areolar (SA) lymphoscintigraphy (LSG) identifies the same sentinel node as peri-tumoural (PT) injections.
It is commonly believed that all LSG techniques will identify the same sentinel lymph nodes (SLN) draining the breast. Hybrid imaging technology (SPECT/CT) allows accurate identification of the exact location of SLNs. Using SPECT/CT SA and PT LSG techniques were compared.
In a multi-centre trial 39 patients sequentially underwent LSG (SA followed by PT) separated by 2-7 days. Patients were referred by 4 surgeons to 3 LSG centres, with standardization of isotope (99mTc-antimony sulfide colloid), LSG and SPECT/CT evaluation techniques. LSG were evaluated for SLN concordance and degree of discordance in the axilla and internal mammary nodes (IMN).
39 eligible patients, median age 62 years, were recruited. Successful axillary SLN mapping for SA and PT injection techniques was 87% and 95% respectively. Successful internal mammary SLN mapping occurred with SA and PT LSG in 5% and 36% respectively. Discordance was identified in the IMN (39%) and axilla (21%), with an overall rate of discordance between SA and PT LSG of 56%.
There is a high level of discordance in the localization of SLN by these commonly used LSG injection techniques. This discordance has implications for accuracy of axillary and extra-axillary staging and could impact on patient outcome. OBJECTIVETo test the hypothesis that sub-areolar (SA) lymphoscintigraphy (LSG) identifies the same sentinel node as peri-tumoural (PT) injections.BACKGROUNDIt is commonly believed that all LSG techniques will identify the same sentinel lymph nodes (SLN) draining the breast. Hybrid imaging technology (SPECT/CT) allows accurate identification of the exact location of SLNs. Using SPECT/CT SA and PT LSG techniques were compared.METHODIn a multi-centre trial 39 patients sequentially underwent LSG (SA followed by PT) separated by 2-7 days. Patients were referred by 4 surgeons to 3 LSG centres, with standardization of isotope (99mTc-antimony sulfide colloid), LSG and SPECT/CT evaluation techniques. LSG were evaluated for SLN concordance and degree of discordance in the axilla and internal mammary nodes (IMN).RESULTS39 eligible patients, median age 62 years, were recruited. Successful axillary SLN mapping for SA and PT injection techniques was 87% and 95% respectively. Successful internal mammary SLN mapping occurred with SA and PT LSG in 5% and 36% respectively. Discordance was identified in the IMN (39%) and axilla (21%), with an overall rate of discordance between SA and PT LSG of 56%.CONCLUSIONSThere is a high level of discordance in the localization of SLN by these commonly used LSG injection techniques. This discordance has implications for accuracy of axillary and extra-axillary staging and could impact on patient outcome. Abstract Objective To test the hypothesis that sub-areolar (SA) lymphoscintigraphy (LSG) identifies the same sentinel node as peri-tumoural (PT) injections. Background It is commonly believed that all LSG techniques will identify the same sentinel lymph nodes (SLN) draining the breast. Hybrid imaging technology (SPECT/CT) allows accurate identification of the exact location of SLNs. Using SPECT/CT SA and PT LSG techniques were compared. Method In a multi-centre trial 39 patients sequentially underwent LSG (SA followed by PT) separated by 2–7 days. Patients were referred by 4 surgeons to 3 LSG centres, with standardization of isotope (99mTc-antimony sulfide colloid), LSG and SPECT/CT evaluation techniques. LSG were evaluated for SLN concordance and degree of discordance in the axilla and internal mammary nodes (IMN). Results 39 eligible patients, median age 62 years, were recruited. Successful axillary SLN mapping for SA and PT injection techniques was 87% and 95% respectively. Successful internal mammary SLN mapping occurred with SA and PT LSG in 5% and 36% respectively. Discordance was identified in the IMN (39%) and axilla (21%), with an overall rate of discordance between SA and PT LSG of 56%. Conclusions There is a high level of discordance in the localization of SLN by these commonly used LSG injection techniques. This discordance has implications for accuracy of axillary and extra-axillary staging and could impact on patient outcome. To test the hypothesis that sub-areolar (SA) lymphoscintigraphy (LSG) identifies the same sentinel node as peri-tumoural (PT) injections. It is commonly believed that all LSG techniques will identify the same sentinel lymph nodes (SLN) draining the breast. Hybrid imaging technology (SPECT/CT) allows accurate identification of the exact location of SLNs. Using SPECT/CT SA and PT LSG techniques were compared. In a multi-centre trial 39 patients sequentially underwent LSG (SA followed by PT) separated by 2–7 days. Patients were referred by 4 surgeons to 3 LSG centres, with standardization of isotope (99mTc-antimony sulfide colloid), LSG and SPECT/CT evaluation techniques. LSG were evaluated for SLN concordance and degree of discordance in the axilla and internal mammary nodes (IMN). 39 eligible patients, median age 62 years, were recruited. Successful axillary SLN mapping for SA and PT injection techniques was 87% and 95% respectively. Successful internal mammary SLN mapping occurred with SA and PT LSG in 5% and 36% respectively. Discordance was identified in the IMN (39%) and axilla (21%), with an overall rate of discordance between SA and PT LSG of 56%. There is a high level of discordance in the localization of SLN by these commonly used LSG injection techniques. This discordance has implications for accuracy of axillary and extra-axillary staging and could impact on patient outcome. |
Author | Gebski, V Allwright, S Spillane, A.J Uren, R.F Cooper, R Pearce, A.M Gillet, D Snook, K.L Noushi, F |
Author_xml | – sequence: 1 fullname: Noushi, F – sequence: 2 fullname: Spillane, A.J – sequence: 3 fullname: Uren, R.F – sequence: 4 fullname: Cooper, R – sequence: 5 fullname: Allwright, S – sequence: 6 fullname: Snook, K.L – sequence: 7 fullname: Gillet, D – sequence: 8 fullname: Pearce, A.M – sequence: 9 fullname: Gebski, V |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/23871572$$D View this record in MEDLINE/PubMed |
BookMark | eNp9kU1v1DAURS1URKeFP9AFypJNgj-S2JYQEhoVilSJBbRby3ZeOk4TO9gJ1fx7HE1hwYLV25x7pXveBTrzwQNCVwRXBJP2_VDBkEJFMWEVbiuM2xdoRxpGS0oafoZ2mNei5FKwc3SR0oAxlozLV-icMsEzQnfo_sY9HIrOJRtip72FIuoFUmFgeQLwRVpNqSOEUcdC-66YIbpyWaewRj0WJoJOSzEep_kQknV-cQ9Rz4fja_Sy12OCN8_3Et19vv6xvylvv335uv90W9qakKWUQjYdpjURVkPbMAG87yUxjQUmOyMaZpjVFhshjdVGEs6pqaWlvK1ln6deonen3jmGnyukRU15Coyj9hDWpEjNeMM5ZyKj9ITaGFKK0Ks5uknHoyJYbT7VoDafavOpcKuyzxx6-9y_mgm6v5E_AjPw4QRAXvnLQVRZA2SPnYtgF9UF9__-j__E7ei8s3p8hCOkIWv22Z8iKlGF1ffto9tDCcO4Ji1lvwGP4Z6K |
CitedBy_id | crossref_primary_10_1016_j_ejso_2013_11_004 crossref_primary_10_1111_ans_16402 crossref_primary_10_1002_jmrs_97 crossref_primary_10_1007_s40336_023_00587_z crossref_primary_10_23736_S1824_4785_21_03286_6 crossref_primary_10_1111_ans_12527 crossref_primary_10_4103_2454_6798_173283 crossref_primary_10_1016_j_addr_2023_114902 crossref_primary_10_1148_rg_2017160166 crossref_primary_10_4236_abcr_2014_34019 crossref_primary_10_1259_bjr_20150634 crossref_primary_10_1007_s10549_014_2866_1 crossref_primary_10_1016_j_breastdis_2013_10_013 crossref_primary_10_1111_ans_18079 crossref_primary_10_1002_jmrs_94 crossref_primary_10_1016_j_breast_2016_08_006 crossref_primary_10_1002_jso_23915 |
Cites_doi | 10.1200/JCO.2000.18.15.2828 10.1093/annonc/mdn725 10.1097/01.sla.0000128304.13522.00 10.1200/JCO.2003.12.047 10.1016/j.ijrobp.2011.09.016 10.1245/s10434-007-9709-9 10.1016/S0959-8049(99)00133-1 10.1214/ss/1009213286 10.1097/00000658-199906000-00013 10.1016/S1072-7515(00)00776-6 10.1016/0960-7404(93)90064-6 10.1053/ejso.2002.1269 10.1001/jama.2011.90 10.1016/j.breast.2011.11.007 10.2967/jnumed.107.043372 10.1001/archsurg.139.6.614 10.1016/j.amjsurg.2007.08.024 10.1200/JCO.2005.06.052 10.1016/j.breast.2010.12.008 10.1002/1097-0142(197601)37:1<206::AID-CNCR2820370130>3.0.CO;2-M 10.1016/S1470-2045(13)70035-4 10.1016/j.ijrobp.2007.08.064 10.1245/s10434-006-9231-5 10.1200/JCO.1998.16.4.1363 10.1097/SLA.0b013e3181f08f32 10.1148/radiol.2282020651 10.2307/2531892 10.1093/annonc/mdn183 10.1016/j.ejso.2009.09.006 10.1093/jnci/djk064 10.1016/S0140-6736(11)61629-2 |
ContentType | Journal Article |
Copyright | Elsevier Ltd 2013 Elsevier Ltd Copyright © 2013 Elsevier Ltd. All rights reserved. |
Copyright_xml | – notice: Elsevier Ltd – notice: 2013 Elsevier Ltd – notice: Copyright © 2013 Elsevier Ltd. All rights reserved. |
DBID | CGR CUY CVF ECM EIF NPM AAYXX CITATION 7X8 |
DOI | 10.1016/j.ejso.2013.06.006 |
DatabaseName | Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed CrossRef MEDLINE - Academic |
DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) CrossRef MEDLINE - Academic |
DatabaseTitleList | MEDLINE MEDLINE - Academic |
Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Medicine |
EISSN | 1532-2157 |
EndPage | 1060 |
ExternalDocumentID | 10_1016_j_ejso_2013_06_006 23871572 S0748798313004162 1_s2_0_S0748798313004162 |
Genre | Research Support, Non-U.S. Gov't Multicenter Study Journal Article |
GroupedDBID | --- --K --M .1- .55 .FO .GJ .~1 0R~ 1B1 1P~ 1~. 1~5 4.4 457 4G. 53G 5GY 5RE 5VS 7-5 71M 8P~ AABNK AACTN AAEDT AAEDW AAIKJ AAKOC AALRI AAOAW AAQFI AAQXK AAXKI AAXUO ABBQC ABFNM ABMAC ABMZM ABXDB ACDAQ ACRLP ADBBV ADEZE ADMUD AEBSH AEKER AENEX AEVXI AFCTW AFJKZ AFKWA AFRHN AFTJW AFXIZ AGHFR AGUBO AGYEJ AIEXJ AIKHN AITUG AJOXV AJRQY AJUYK AKRWK ALMA_UNASSIGNED_HOLDINGS AMFUW AMRAJ ANZVX ASPBG AVWKF AXJTR AZFZN BKOJK BLXMC BNPGV CAG COF CS3 DU5 EBS EFJIC EJD EO8 EO9 EP2 EP3 F5P FDB FEDTE FGOYB FIRID FNPLU FYGXN G-Q GBLVA HVGLF HZ~ IHE J1W J5H K-O KOM L7B M41 MO0 N9A O-L O9- OAUVE OK- OW- OZT P-8 P-9 P2P PC. Q38 R2- RIG ROL RPZ SDF SDG SEL SES SEW SPCBC SSH SSZ T5K UDS UHS UV1 X7M Z5R ZGI ZXP ~G- AAIAV ABLVK ABYKQ AHPSJ AJBFU EFLBG LCYCR CGR CUY CVF ECM EIF NPM AAYXX CITATION 7X8 |
ID | FETCH-LOGICAL-c411t-9895d02418cae6538e7ff91b5ce39db853b3cac0b89bcab91772b49c27649f153 |
IEDL.DBID | AIKHN |
ISSN | 0748-7983 |
IngestDate | Sat Oct 05 05:02:26 EDT 2024 Thu Sep 26 18:04:49 EDT 2024 Sat Sep 28 07:54:06 EDT 2024 Fri Feb 23 02:21:17 EST 2024 Tue Oct 15 22:56:44 EDT 2024 |
IsPeerReviewed | true |
IsScholarly | true |
Issue | 10 |
Keywords | Axilla Internal mammary Breast cancer SPECT/CT lymphoscintigraphy Sentinel lymph node |
Language | English |
License | Copyright © 2013 Elsevier Ltd. All rights reserved. |
LinkModel | DirectLink |
MergedId | FETCHMERGED-LOGICAL-c411t-9895d02418cae6538e7ff91b5ce39db853b3cac0b89bcab91772b49c27649f153 |
Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
PMID | 23871572 |
PQID | 1437577738 |
PQPubID | 23479 |
PageCount | 8 |
ParticipantIDs | proquest_miscellaneous_1437577738 crossref_primary_10_1016_j_ejso_2013_06_006 pubmed_primary_23871572 elsevier_sciencedirect_doi_10_1016_j_ejso_2013_06_006 elsevier_clinicalkeyesjournals_1_s2_0_S0748798313004162 |
PublicationCentury | 2000 |
PublicationDate | 2013-10-01 |
PublicationDateYYYYMMDD | 2013-10-01 |
PublicationDate_xml | – month: 10 year: 2013 text: 2013-10-01 day: 01 |
PublicationDecade | 2010 |
PublicationPlace | England |
PublicationPlace_xml | – name: England |
PublicationTitle | European journal of surgical oncology |
PublicationTitleAlternate | Eur J Surg Oncol |
PublicationYear | 2013 |
Publisher | Elsevier Ltd |
Publisher_xml | – name: Elsevier Ltd |
References | Galimberti, Cole, Zurrida (bib33) 2013; 14 Klimberg, Rubio, Henry (bib1) 1999; 229 Tanis, Nieweg, Valdes Olmos, Kroon (bib7) 2001; 192 Noushi, Spillane, Uren, Gebski (bib14) 2010; 36 Uren, Howman-Giles, Chung (bib4) 2012; 21 Brown, Cai, DasGupta (bib11) 2001; 16 Giuliano, Hunt, Ballman (bib16) 2011; 305 Veronesi, Marubini, Mariani, Valagussa, Zucali (bib23) 1999; 35 Suami, Pan, Mann, Taylor (bib6) 2008; 15 Colleoni, Zahrieh, Gelber (bib24) 2005; 23 Layeeque, Kepple, Henry-Tillman (bib13) 2004; 239 Spillane, Noushi, Cooper, Gebski, Uren (bib5) 2009; 20 Rabinovitch, Ballonoff, Newman, Finlayson (bib15) 2008; 70 Bevilacqua, Gucciardo, Cody (bib21) 2002; 28 Hooning, Botma, Aleman (bib29) 2007; 99 Tanis, Valdes Olmos, Muller, Nieweg (bib9) 2003; 228 Lohrisch, Jackson, Jones, Mates, Olivotto (bib26) 2000; 18 Krag, Weaver, Alex (bib12) 1993; 2 Gaffney, Tsodikov, Wiggins (bib25) 2003; 21 Zucali, Mariani, Marubini (bib28) 1998; 16 Veronesi, Arnone, Veronesi (bib32) 2008; 19 Pelosi, Bello, Giors (bib2) 2004; 45 Hindie, Groheux, Hennequin (bib30) 2012; 83 Lacour, Bucalossi, Cacers (bib22) 1976; 37 Giuliano, McCall, Beitsch (bib17) 2010; 252 Chagpar, Carlson, Laidley (bib19) 2007; 194 Noushi, Spillane, Uren, Gebski (bib31) 2011; 20 Darby, McGale, Correa (bib18) 2011; 378 van der Ploeg, Valdes Olmos, Nieweg (bib8) 2007; 48 Sarp, Fioretta, Verkooijen (bib27) 2007; 14 Rice (bib10) 1988; 44 Chagpar, Martin, Chao (bib3) 2004; 139 Eur J Surg Oncol. 2014 Feb;40(2):246 Lacour (10.1016/j.ejso.2013.06.006_bib22) 1976; 37 van der Ploeg (10.1016/j.ejso.2013.06.006_bib8) 2007; 48 Noushi (10.1016/j.ejso.2013.06.006_bib14) 2010; 36 Rice (10.1016/j.ejso.2013.06.006_bib10) 1988; 44 Chagpar (10.1016/j.ejso.2013.06.006_bib19) 2007; 194 Veronesi (10.1016/j.ejso.2013.06.006_bib32) 2008; 19 Krag (10.1016/j.ejso.2013.06.006_bib12) 1993; 2 Gaffney (10.1016/j.ejso.2013.06.006_bib25) 2003; 21 Lohrisch (10.1016/j.ejso.2013.06.006_bib26) 2000; 18 Galimberti (10.1016/j.ejso.2013.06.006_bib33) 2013; 14 Pelosi (10.1016/j.ejso.2013.06.006_bib2) 2004; 45 Chagpar (10.1016/j.ejso.2013.06.006_bib3) 2004; 139 Zucali (10.1016/j.ejso.2013.06.006_bib28) 1998; 16 Giuliano (10.1016/j.ejso.2013.06.006_bib17) 2010; 252 Darby (10.1016/j.ejso.2013.06.006_bib18) 2011; 378 Layeeque (10.1016/j.ejso.2013.06.006_bib13) 2004; 239 Veronesi (10.1016/j.ejso.2013.06.006_bib23) 1999; 35 Hooning (10.1016/j.ejso.2013.06.006_bib29) 2007; 99 Hindie (10.1016/j.ejso.2013.06.006_bib30) 2012; 83 Rabinovitch (10.1016/j.ejso.2013.06.006_bib15) 2008; 70 Sarp (10.1016/j.ejso.2013.06.006_bib27) 2007; 14 Klimberg (10.1016/j.ejso.2013.06.006_bib1) 1999; 229 Giuliano (10.1016/j.ejso.2013.06.006_bib16) 2011; 305 Suami (10.1016/j.ejso.2013.06.006_bib6) 2008; 15 Bevilacqua (10.1016/j.ejso.2013.06.006_bib21) 2002; 28 Tanis (10.1016/j.ejso.2013.06.006_bib9) 2003; 228 Colleoni (10.1016/j.ejso.2013.06.006_bib24) 2005; 23 Brown (10.1016/j.ejso.2013.06.006_bib11) 2001; 16 Tanis (10.1016/j.ejso.2013.06.006_bib7) 2001; 192 Spillane (10.1016/j.ejso.2013.06.006_bib5) 2009; 20 Uren (10.1016/j.ejso.2013.06.006_bib4) 2012; 21 Noushi (10.1016/j.ejso.2013.06.006_bib31) 2011; 20 |
References_xml | – volume: 99 start-page: 365 year: 2007 end-page: 375 ident: bib29 article-title: Long-term risk of cardiovascular disease in 10-year survivors of breast cancer publication-title: J Natl Cancer Inst contributor: fullname: Aleman – volume: 20 start-page: 977 year: 2009 end-page: 984 ident: bib5 article-title: High-resolution lymphoscintigraphy is essential for recognition of the significance of internal mammary nodes in breast cancer publication-title: Ann Oncol contributor: fullname: Uren – volume: 16 start-page: 1363 year: 1998 end-page: 1366 ident: bib28 article-title: Early breast cancer: evaluation of the prognostic role of the site of the primary tumour publication-title: J Clin Oncol contributor: fullname: Marubini – volume: 378 start-page: 1707 year: 2011 end-page: 1716 ident: bib18 article-title: Effect of radiotherapy after breast-conserving surgery on 10-year recurrence and 15-year breast cancer death: meta-analysis of individual patient data for 10,801 women in 17 randomised trials publication-title: Lancet contributor: fullname: Correa – volume: 14 start-page: 297 year: 2013 end-page: 305 ident: bib33 article-title: Axillary dissection versus no axillary dissection in patients with sentinel-node micrometastases (IBCSG 23-01): a phase 3 randomised controlled trial publication-title: Lancet Oncol contributor: fullname: Zurrida – volume: 16 start-page: 101 year: 2001 end-page: 133 ident: bib11 article-title: Interval estimation for a binomial proportion publication-title: Stat Sci contributor: fullname: DasGupta – volume: 14 start-page: 1031 year: 2007 end-page: 1039 ident: bib27 article-title: Tumour location of the lower-inner quadrant is associated with an impaired survival for women with early-stage breast cancer publication-title: Ann Surg Oncol contributor: fullname: Verkooijen – volume: 21 start-page: 467 year: 2003 end-page: 472 ident: bib25 article-title: Diminished survival in patients with inner versus outer quadrant breast cancers publication-title: J Clin Oncol contributor: fullname: Wiggins – volume: 44 start-page: 1 year: 1988 end-page: 22 ident: bib10 article-title: A new probability model for determining exact P-values for 2 × 2 tables when comparing binomial proportions publication-title: Biometrics contributor: fullname: Rice – volume: 70 start-page: 1468 year: 2008 end-page: 1471 ident: bib15 article-title: Evaluation of breast sentinel lymph node coverage by standard radiation therapy fields publication-title: Int J Radiat Oncol Biol Phys contributor: fullname: Finlayson – volume: 2 start-page: 335 year: 1993 end-page: 340 ident: bib12 article-title: Surgical resection and radiolocalization of the sentinel lymph node in breast cancer using gamma probe publication-title: Surg Oncol contributor: fullname: Alex – volume: 45 start-page: 220 year: 2004 end-page: 225 ident: bib2 article-title: Sentinel lymph node detection in patients with early-stage breast cancer: comparison of periareolar and subdermal/peritumoural injection techniques publication-title: J Nucl Med contributor: fullname: Giors – volume: 21 start-page: 480 year: 2012 end-page: 486 ident: bib4 article-title: SPECT/CT scans allow precise anatomical location of sentinel lymph nodes in breast cancer and redefine lymphatic drainage from the breast to the axilla publication-title: Breast contributor: fullname: Chung – volume: 18 start-page: 2828 year: 2000 end-page: 2835 ident: bib26 article-title: Relationship between tumour location and relapse in 6,781 women with early invasive breast cancer publication-title: J Clin Oncol contributor: fullname: Olivotto – volume: 229 start-page: 860 year: 1999 end-page: 864 ident: bib1 article-title: Subareolar versus peritumoural injection for location of the sentinel lymph node publication-title: Ann Surg contributor: fullname: Henry – volume: 228 start-page: 546 year: 2003 end-page: 551 ident: bib9 article-title: Lymphatic mapping in patients with breast carcinoma: reproducibility of lymphoscintigraphic results publication-title: Radiology contributor: fullname: Nieweg – volume: 23 start-page: 1390 year: 2005 end-page: 1400 ident: bib24 article-title: Site of primary tumour has a prognostic role in operable breast cancer: the international breast cancer study group experience publication-title: J Clin Oncol contributor: fullname: Gelber – volume: 15 start-page: 863 year: 2008 end-page: 871 ident: bib6 article-title: The lymphatic anatomy of the breast and its implications for sentinel lymph node biopsy: a human cadaver study publication-title: Ann Surg Oncol contributor: fullname: Taylor – volume: 139 start-page: 614 year: 2004 end-page: 618 ident: bib3 article-title: Validation of subareolar and periareolar injection techniques for breast sentinel lymph node biopsy publication-title: Arch Surg contributor: fullname: Chao – volume: 305 start-page: 569 year: 2011 end-page: 575 ident: bib16 article-title: Axillary dissection vs no axillary dissection in women with invasive breast cancer and sentinel node metastasis: a randomized clinical trial publication-title: J Am Med Assoc contributor: fullname: Ballman – volume: 252 start-page: 426 year: 2010 end-page: 432 ident: bib17 article-title: Locoregional recurrence after sentinel lymph node dissection with or without axillary dissection in patients with sentinel lymph node metastases: the American College of Surgeons Oncology Group Z0011 randomized trial publication-title: Ann Surg contributor: fullname: Beitsch – volume: 28 start-page: 603 year: 2002 end-page: 614 ident: bib21 article-title: A selection algorithm for internal mammary sentinel lymph node biopsy in breast cancer publication-title: Eur J Surg Oncol contributor: fullname: Cody – volume: 194 start-page: 860 year: 2007 end-page: 864 ident: bib19 article-title: Factors influencing the number of sentinel lymph nodes identified in patients with breast cancer publication-title: Am J Surg contributor: fullname: Laidley – volume: 37 start-page: 206 year: 1976 end-page: 214 ident: bib22 article-title: Radical mastectomy versus radical mastectomy plus internal mammary dissection. Five-year results of an international cooperative study publication-title: Cancer contributor: fullname: Cacers – volume: 35 start-page: 1320 year: 1999 end-page: 1325 ident: bib23 article-title: The dissection of internal mammary nodes does not improve the survival of breast cancer patients. 30-year results of a randomised trial publication-title: Eur J Cancer contributor: fullname: Zucali – volume: 36 start-page: 16 year: 2010 end-page: 22 ident: bib14 article-title: Internal mammary node metastasis in breast cancer: predictive models to determine status & management algorithms publication-title: Eur J Surg Oncol contributor: fullname: Gebski – volume: 192 start-page: 399 year: 2001 end-page: 409 ident: bib7 article-title: Anatomy and physiology of lymphatic drainage of the breast from the perspective of sentinel node biopsy publication-title: J Am Coll Surg contributor: fullname: Kroon – volume: 239 start-page: 841 year: 2004 end-page: 845 ident: bib13 article-title: Intraoperative subareolar radioisotope injection for immediate sentinel lymph node biopsy publication-title: Ann Surg contributor: fullname: Henry-Tillman – volume: 48 start-page: 1756 year: 2007 end-page: 1760 ident: bib8 article-title: The additional value of SPECT/CT in lymphatic mapping in breast cancer and melanoma publication-title: J Nucl Med contributor: fullname: Nieweg – volume: 83 start-page: 1081 year: 2012 end-page: 1088 ident: bib30 article-title: Lymphoscintigraphy can select breast cancer patients for internal mammary chain radiotherapy publication-title: Int J Radiat Oncol Biol Phys contributor: fullname: Hennequin – volume: 20 start-page: 278 year: 2011 end-page: 283 ident: bib31 article-title: Internal mammary lymph node metastasis in breast cancer: predictive models to assist with prognostic influence publication-title: Breast contributor: fullname: Gebski – volume: 19 start-page: 1553 year: 2008 end-page: 1560 ident: bib32 article-title: The value of radiotherapy on metastatic internal mammary nodes in breast cancer. Results on a large series publication-title: Ann Oncol contributor: fullname: Veronesi – volume: 18 start-page: 2828 year: 2000 ident: 10.1016/j.ejso.2013.06.006_bib26 article-title: Relationship between tumour location and relapse in 6,781 women with early invasive breast cancer publication-title: J Clin Oncol doi: 10.1200/JCO.2000.18.15.2828 contributor: fullname: Lohrisch – volume: 45 start-page: 220 year: 2004 ident: 10.1016/j.ejso.2013.06.006_bib2 article-title: Sentinel lymph node detection in patients with early-stage breast cancer: comparison of periareolar and subdermal/peritumoural injection techniques publication-title: J Nucl Med contributor: fullname: Pelosi – volume: 20 start-page: 977 year: 2009 ident: 10.1016/j.ejso.2013.06.006_bib5 article-title: High-resolution lymphoscintigraphy is essential for recognition of the significance of internal mammary nodes in breast cancer publication-title: Ann Oncol doi: 10.1093/annonc/mdn725 contributor: fullname: Spillane – volume: 239 start-page: 841 year: 2004 ident: 10.1016/j.ejso.2013.06.006_bib13 article-title: Intraoperative subareolar radioisotope injection for immediate sentinel lymph node biopsy publication-title: Ann Surg doi: 10.1097/01.sla.0000128304.13522.00 contributor: fullname: Layeeque – volume: 21 start-page: 467 year: 2003 ident: 10.1016/j.ejso.2013.06.006_bib25 article-title: Diminished survival in patients with inner versus outer quadrant breast cancers publication-title: J Clin Oncol doi: 10.1200/JCO.2003.12.047 contributor: fullname: Gaffney – volume: 83 start-page: 1081 year: 2012 ident: 10.1016/j.ejso.2013.06.006_bib30 article-title: Lymphoscintigraphy can select breast cancer patients for internal mammary chain radiotherapy publication-title: Int J Radiat Oncol Biol Phys doi: 10.1016/j.ijrobp.2011.09.016 contributor: fullname: Hindie – volume: 15 start-page: 863 year: 2008 ident: 10.1016/j.ejso.2013.06.006_bib6 article-title: The lymphatic anatomy of the breast and its implications for sentinel lymph node biopsy: a human cadaver study publication-title: Ann Surg Oncol doi: 10.1245/s10434-007-9709-9 contributor: fullname: Suami – volume: 35 start-page: 1320 year: 1999 ident: 10.1016/j.ejso.2013.06.006_bib23 article-title: The dissection of internal mammary nodes does not improve the survival of breast cancer patients. 30-year results of a randomised trial publication-title: Eur J Cancer doi: 10.1016/S0959-8049(99)00133-1 contributor: fullname: Veronesi – volume: 16 start-page: 101 year: 2001 ident: 10.1016/j.ejso.2013.06.006_bib11 article-title: Interval estimation for a binomial proportion publication-title: Stat Sci doi: 10.1214/ss/1009213286 contributor: fullname: Brown – volume: 229 start-page: 860 year: 1999 ident: 10.1016/j.ejso.2013.06.006_bib1 article-title: Subareolar versus peritumoural injection for location of the sentinel lymph node publication-title: Ann Surg doi: 10.1097/00000658-199906000-00013 contributor: fullname: Klimberg – volume: 192 start-page: 399 year: 2001 ident: 10.1016/j.ejso.2013.06.006_bib7 article-title: Anatomy and physiology of lymphatic drainage of the breast from the perspective of sentinel node biopsy publication-title: J Am Coll Surg doi: 10.1016/S1072-7515(00)00776-6 contributor: fullname: Tanis – volume: 2 start-page: 335 year: 1993 ident: 10.1016/j.ejso.2013.06.006_bib12 article-title: Surgical resection and radiolocalization of the sentinel lymph node in breast cancer using gamma probe publication-title: Surg Oncol doi: 10.1016/0960-7404(93)90064-6 contributor: fullname: Krag – volume: 28 start-page: 603 year: 2002 ident: 10.1016/j.ejso.2013.06.006_bib21 article-title: A selection algorithm for internal mammary sentinel lymph node biopsy in breast cancer publication-title: Eur J Surg Oncol doi: 10.1053/ejso.2002.1269 contributor: fullname: Bevilacqua – volume: 305 start-page: 569 year: 2011 ident: 10.1016/j.ejso.2013.06.006_bib16 article-title: Axillary dissection vs no axillary dissection in women with invasive breast cancer and sentinel node metastasis: a randomized clinical trial publication-title: J Am Med Assoc doi: 10.1001/jama.2011.90 contributor: fullname: Giuliano – volume: 21 start-page: 480 year: 2012 ident: 10.1016/j.ejso.2013.06.006_bib4 article-title: SPECT/CT scans allow precise anatomical location of sentinel lymph nodes in breast cancer and redefine lymphatic drainage from the breast to the axilla publication-title: Breast doi: 10.1016/j.breast.2011.11.007 contributor: fullname: Uren – volume: 48 start-page: 1756 year: 2007 ident: 10.1016/j.ejso.2013.06.006_bib8 article-title: The additional value of SPECT/CT in lymphatic mapping in breast cancer and melanoma publication-title: J Nucl Med doi: 10.2967/jnumed.107.043372 contributor: fullname: van der Ploeg – volume: 139 start-page: 614 year: 2004 ident: 10.1016/j.ejso.2013.06.006_bib3 article-title: Validation of subareolar and periareolar injection techniques for breast sentinel lymph node biopsy publication-title: Arch Surg doi: 10.1001/archsurg.139.6.614 contributor: fullname: Chagpar – volume: 194 start-page: 860 year: 2007 ident: 10.1016/j.ejso.2013.06.006_bib19 article-title: Factors influencing the number of sentinel lymph nodes identified in patients with breast cancer publication-title: Am J Surg doi: 10.1016/j.amjsurg.2007.08.024 contributor: fullname: Chagpar – volume: 23 start-page: 1390 year: 2005 ident: 10.1016/j.ejso.2013.06.006_bib24 article-title: Site of primary tumour has a prognostic role in operable breast cancer: the international breast cancer study group experience publication-title: J Clin Oncol doi: 10.1200/JCO.2005.06.052 contributor: fullname: Colleoni – volume: 20 start-page: 278 year: 2011 ident: 10.1016/j.ejso.2013.06.006_bib31 article-title: Internal mammary lymph node metastasis in breast cancer: predictive models to assist with prognostic influence publication-title: Breast doi: 10.1016/j.breast.2010.12.008 contributor: fullname: Noushi – volume: 37 start-page: 206 year: 1976 ident: 10.1016/j.ejso.2013.06.006_bib22 article-title: Radical mastectomy versus radical mastectomy plus internal mammary dissection. Five-year results of an international cooperative study publication-title: Cancer doi: 10.1002/1097-0142(197601)37:1<206::AID-CNCR2820370130>3.0.CO;2-M contributor: fullname: Lacour – volume: 14 start-page: 297 year: 2013 ident: 10.1016/j.ejso.2013.06.006_bib33 article-title: Axillary dissection versus no axillary dissection in patients with sentinel-node micrometastases (IBCSG 23-01): a phase 3 randomised controlled trial publication-title: Lancet Oncol doi: 10.1016/S1470-2045(13)70035-4 contributor: fullname: Galimberti – volume: 70 start-page: 1468 year: 2008 ident: 10.1016/j.ejso.2013.06.006_bib15 article-title: Evaluation of breast sentinel lymph node coverage by standard radiation therapy fields publication-title: Int J Radiat Oncol Biol Phys doi: 10.1016/j.ijrobp.2007.08.064 contributor: fullname: Rabinovitch – volume: 14 start-page: 1031 year: 2007 ident: 10.1016/j.ejso.2013.06.006_bib27 article-title: Tumour location of the lower-inner quadrant is associated with an impaired survival for women with early-stage breast cancer publication-title: Ann Surg Oncol doi: 10.1245/s10434-006-9231-5 contributor: fullname: Sarp – volume: 16 start-page: 1363 year: 1998 ident: 10.1016/j.ejso.2013.06.006_bib28 article-title: Early breast cancer: evaluation of the prognostic role of the site of the primary tumour publication-title: J Clin Oncol doi: 10.1200/JCO.1998.16.4.1363 contributor: fullname: Zucali – volume: 252 start-page: 426 year: 2010 ident: 10.1016/j.ejso.2013.06.006_bib17 article-title: Locoregional recurrence after sentinel lymph node dissection with or without axillary dissection in patients with sentinel lymph node metastases: the American College of Surgeons Oncology Group Z0011 randomized trial publication-title: Ann Surg doi: 10.1097/SLA.0b013e3181f08f32 contributor: fullname: Giuliano – volume: 228 start-page: 546 year: 2003 ident: 10.1016/j.ejso.2013.06.006_bib9 article-title: Lymphatic mapping in patients with breast carcinoma: reproducibility of lymphoscintigraphic results publication-title: Radiology doi: 10.1148/radiol.2282020651 contributor: fullname: Tanis – volume: 44 start-page: 1 year: 1988 ident: 10.1016/j.ejso.2013.06.006_bib10 article-title: A new probability model for determining exact P-values for 2 × 2 tables when comparing binomial proportions publication-title: Biometrics doi: 10.2307/2531892 contributor: fullname: Rice – volume: 19 start-page: 1553 year: 2008 ident: 10.1016/j.ejso.2013.06.006_bib32 article-title: The value of radiotherapy on metastatic internal mammary nodes in breast cancer. Results on a large series publication-title: Ann Oncol doi: 10.1093/annonc/mdn183 contributor: fullname: Veronesi – volume: 36 start-page: 16 year: 2010 ident: 10.1016/j.ejso.2013.06.006_bib14 article-title: Internal mammary node metastasis in breast cancer: predictive models to determine status & management algorithms publication-title: Eur J Surg Oncol doi: 10.1016/j.ejso.2009.09.006 contributor: fullname: Noushi – volume: 99 start-page: 365 year: 2007 ident: 10.1016/j.ejso.2013.06.006_bib29 article-title: Long-term risk of cardiovascular disease in 10-year survivors of breast cancer publication-title: J Natl Cancer Inst doi: 10.1093/jnci/djk064 contributor: fullname: Hooning – volume: 378 start-page: 1707 year: 2011 ident: 10.1016/j.ejso.2013.06.006_bib18 article-title: Effect of radiotherapy after breast-conserving surgery on 10-year recurrence and 15-year breast cancer death: meta-analysis of individual patient data for 10,801 women in 17 randomised trials publication-title: Lancet doi: 10.1016/S0140-6736(11)61629-2 contributor: fullname: Darby |
SSID | ssj0009379 |
Score | 2.1974845 |
Snippet | Abstract Objective To test the hypothesis that sub-areolar (SA) lymphoscintigraphy (LSG) identifies the same sentinel node as peri-tumoural (PT) injections.... To test the hypothesis that sub-areolar (SA) lymphoscintigraphy (LSG) identifies the same sentinel node as peri-tumoural (PT) injections. It is commonly... OBJECTIVETo test the hypothesis that sub-areolar (SA) lymphoscintigraphy (LSG) identifies the same sentinel node as peri-tumoural (PT) injections.BACKGROUNDIt... |
SourceID | proquest crossref pubmed elsevier |
SourceType | Aggregation Database Index Database Publisher |
StartPage | 1053 |
SubjectTerms | Adult Aged Axilla Breast cancer Breast Neoplasms - diagnostic imaging Breast Neoplasms - pathology Female Hematology, Oncology and Palliative Medicine Humans Internal mammary Lymphoscintigraphy Middle Aged Radiopharmaceuticals Sentinel lymph node Sentinel Lymph Node Biopsy SPECT/CT lymphoscintigraphy Surgery Technetium Tc 99m Sulfur Colloid Tomography, Emission-Computed, Single-Photon |
Title | High discordance rates between sub-areolar and peri-tumoural breast lymphoscintigraphy |
URI | https://www.clinicalkey.es/playcontent/1-s2.0-S0748798313004162 https://dx.doi.org/10.1016/j.ejso.2013.06.006 https://www.ncbi.nlm.nih.gov/pubmed/23871572 https://search.proquest.com/docview/1437577738 |
Volume | 39 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Lb9QwEB6VrYS4IN5sgZWRuCGz67UTO8dqRbU8WiGgqDfLdmxpK8hWTfbQC7-dmcQpQjwOHBMlcTJjfzOjfPMZ4IUzQZSmLrkuk-KqdjWvlFtwRzQbo6tQ1tTvfHxSrk_V27PibA9WYy8M0Soz9g-Y3qN1PjPP1pxfbDbzTxj88GFGil40inB4H8ORUhPYP3zzbn3yU3s3S-7h9ZxuyL0zA80rnrfUAyhkL-NJGx_9OT79Lf_s49DRHbidE0h2OLzjXdiLzT24eZx_kd-HL8TcYNRsi2UluZSRGETLMiGLtTvP3WWkipa5pmakdMy73bct6W8wTxz1jn29QieTzGXTbQZJ6wdwevT682rN8-YJPCghOl6ZqqgxAAsTXCwR1qJOqRK-CFFWtcco7WVwYeFN5YPzWLXppVdVWOpSVQlx8CFMmm0THwNLffup1DJhLuBdMC4VPiSJtYbE-jJN4eVoMnsxaGTYkTx2bsnAlgxsewZdOQU9WtWO3Z-IV7HNi6e1wrZLu7C_OXgKxfWdv8wRi_D_zxGfj86zuHjoj4hr4naHIympC621NFN4NHj1-gswl9Gi0MuD_xz1Cdyio4H49xQm3eUuPsMEpvMzuPHqu5jhNF19fP9hlqfrDzRY8Jo |
link.rule.ids | 315,786,790,4521,24144,27955,27956,45618,45712 |
linkProvider | Elsevier |
linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Lb9QwEB5VRSpcKiiPLq8aiRsyu14nsX1EFdX2sb3Qot4s27Glraq02mQPXPjtzCROEeJx4JqHnczE38zI33wBeO90EJWuK66qVPCidjU3hZtxRzQbrUyoaup3Xp5Xi8vi5Kq82oLDsReGaJUZ-wdM79E6H5lma07vVqvpFwx-OJiWoheNIhx-QNkA8bo-fv_J8zBZcA-v5nR57pwZSF7xuqUOQCF7EU_67dGfo9Pfss8-Ch09ht2cPrJPwxM-ga3Y7MHOMm-QP4WvxNtg1GqLRSU5lJEURMsyHYu1G8_dOlI9y1xTM9I55t0G6_81DuuJod6xm2_oYhK5bLrVIGj9DC6PPl8cLnj-dQIPhRAdN9qUNYZfoYOLFYJaVCkZ4csQpak9xmgvgwszr40PzmPNpua-MGGuqsIkRMHnsN3cNnEfWOqbT6WSCTMB74J2qfQhSaw0JFaXaQIfRpPZu0Ehw47UsWtLBrZkYNvz56oJqNGqduz9RLSKbV46rRW2nduZ_c29Eyjv7_zlC7EI_v-c8d3oPItLh_ZDXBNvNzhTIVWplJJ6Ai8Gr96_AWYySpRq_vI_Zz2Ah4uL5Zk9Oz4_fQWP6MxAAXwN2916E99gKtP5t_2n-gPVPu_a |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=High+discordance+rates+between+sub-areolar+and+peri-tumoural+breast+lymphoscintigraphy&rft.jtitle=European+journal+of+surgical+oncology&rft.au=Noushi%2C+F&rft.au=Spillane%2C+A+J&rft.au=Uren%2C+R+F&rft.au=Cooper%2C+R&rft.date=2013-10-01&rft.eissn=1532-2157&rft.volume=39&rft.issue=10&rft.spage=1053&rft_id=info:doi/10.1016%2Fj.ejso.2013.06.006&rft_id=info%3Apmid%2F23871572&rft.externalDocID=23871572 |
thumbnail_m | http://utb.summon.serialssolutions.com/2.0.0/image/custom?url=https%3A%2F%2Fcdn.clinicalkey.com%2Fck-thumbnails%2F07487983%2FS0748798313X00101%2Fcov150h.gif |