Postoperative irrigation with bisphosphonates may reduce the recurrence of giant cell tumor of bone

• Published in: Medical hypotheses Vol. 81; no. 5; pp. 851 - 852
• Main Authors: Yang, Tao, Zheng, Xiao-Fei, Lin, Xi, Yin, Qing-Shui
• Format: Journal Article
• Language: English
• Published: United States Elsevier Ltd 01.11.2013
• Subjects: Diphosphonates - administration & dosage; Diphosphonates - therapeutic use; Giant Cell Tumor of Bone - prevention & control; Giant Cell Tumor of Bone - surgery; Humans; Internal Medicine; Models, Biological; Neoplasm Recurrence, Local - prevention & control; Postoperative Care - methods; Therapeutic Irrigation - methods

Abstract Giant cell tumor of bone (GCTB) is a common benign bone tumor characterized by local osteolysis and high proclivity for recurrence. Surgical excision is the preferred treatment. However, simple wide resection may cause functional and cosmetic deformities of the skeleton. Currently, intrales...