Meta-GDBP: a high-level stacked regression model to improve anticancer drug response prediction

• Published in: Briefings in bioinformatics Vol. 21; no. 3; pp. 996 - 1005
• Main Authors: Su, Ran, Liu, Xinyi, Xiao, Guobao, Wei, Leyi
• Format: Journal Article
• Language: English
• Published: England Oxford University Press 21.05.2020; Oxford Publishing Limited (England)
• Subjects: Biological properties; Cancer; Chemical properties; Context; Encyclopedias; Optimization; Precision medicine; Predictions; Regression models; genetic; Meta-GDBP; biological context; chemical; anticancer drug response

Abstract Anticancer drug response prediction plays an important role in personalized medicine. In particular, precisely predicting drug response in specific cancer types and patients is still a challenge problem. Here we propose Meta-GDBP, a novel anticancer drug-response model, which involves two l...