The effect of paramagnetic contrast in choline peak in patients with glioblastoma multiforme might not be significant

• Published in: American journal of neuroradiology : AJNR Vol. 34; no. 1; pp. 80 - 84
• Main Authors: Lima, E C, Otaduy, M C G, Tsunemi, M, Pincerato, R, Cardoso, E F, Rosemberg, S, Aguiar, P H, Cerri, G G, Leite, C C
• Format: Journal Article
• Language: English
• Published: United States American Society of Neuroradiology 01.01.2013
• Subjects: Adult; Aged; Aged, 80 and over; Brain; Brain - drug effects; Brain - metabolism; Brain - pathology; Brain Neoplasms - diagnosis; Brain Neoplasms - metabolism; Choline - analysis; Contrast Media - administration & dosage; Electron Spin Resonance Spectroscopy - methods; Female; Gadolinium - administration & dosage; Glioblastoma - diagnosis; Glioblastoma - metabolism; Humans; Male; Middle Aged; Reproducibility of Results; Sensitivity and Specificity

(1)H-MR spectroscopy is a useful tool in brain tumor evaluation. A critical point in obtaining representative spectra is the correct voxel positioning, which can be more accurate after Gd administration. Some experimental data suggested that Gd could cause Cho signal loss. Our aim was to evaluate th...