Prevalence and risk factors for depression and anxiety in adult patients with epilepsy: Caregivers’ anxiety and place of residence do mater
•Adult patients with epilepsy are at a high risk of suffering from anxiety and depression.•Caregivers’ anxiety and place of residence where adult patients with epilepsy live are definite independent predictors for anxiety and depression among adult patients with epilepsy.•Clinicians should be carefu...
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| Published in | Epilepsy & behavior Vol. 129; p. 108628 |
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| Main Authors | , , , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
Elsevier Inc
01.04.2022
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| Subjects | |
| Online Access | Get full text |
| ISSN | 1525-5050 1525-5069 1525-5069 |
| DOI | 10.1016/j.yebeh.2022.108628 |
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| Abstract | •Adult patients with epilepsy are at a high risk of suffering from anxiety and depression.•Caregivers’ anxiety and place of residence where adult patients with epilepsy live are definite independent predictors for anxiety and depression among adult patients with epilepsy.•Clinicians should be careful in closely monitoring the psychological status of adult patients with epilepsy and their caregivers, especially among adult patients with epilepsy who live in rural areas and whose caregivers are suffering from anxiety.
This study was aimed to assess the prevalence of anxiety and depression and the possible contributions of the caregiver’s anxiety and depression, disease status, and socio-demographic characteristics to psychopathological comorbidities among adult patients with epilepsy.
A total of 262 participants (131 adult patient-caregiver pairs) were enrolled in this study. The Hamilton Rating Scale for Depression (HAM-D) and the Hamilton Rating Scale for Anxiety (HAM-A) were applied to evaluate the depression and anxiety status among adult patients with epilepsy and their caregivers, respectively. We collected caregivers’ anxiety and depression, patients’ sociodemographic characteristic data, and disease status as independent variables using stepwise multiple linear regression analysis that were correlated to the degree of anxiety and depression among these adult patients with epilepsy.
Among adult patients with epilepsy, 46 (35.11%) subjects showed anxiety symptoms (HAM-A scores > 6), and 48 (36.64%) had depression symptoms (HAM-D scores > 6). Caregivers’ anxiety levels and place of residence were significant independent predictors of both anxiety and depression levels among adult patients with epilepsy.
Adult patients with epilepsy are at a high risk of suffering from anxiety and depression. Caregivers’ anxiety and place of residence are definite independent predictors for anxiety and depression severity among adult patients with epilepsy. Therefore, clinicians should be careful in closely monitoring the psychological status of adult patients with epilepsy and their caregivers. Furthermore, the government and medical institutions should increase educational awareness about epilepsy and its cure, especially among adult patients with epilepsy who live in rural areas and consider offering a multidisciplinary management program to improve these patients' psychological status. |
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| AbstractList | •Adult patients with epilepsy are at a high risk of suffering from anxiety and depression.•Caregivers’ anxiety and place of residence where adult patients with epilepsy live are definite independent predictors for anxiety and depression among adult patients with epilepsy.•Clinicians should be careful in closely monitoring the psychological status of adult patients with epilepsy and their caregivers, especially among adult patients with epilepsy who live in rural areas and whose caregivers are suffering from anxiety.
This study was aimed to assess the prevalence of anxiety and depression and the possible contributions of the caregiver’s anxiety and depression, disease status, and socio-demographic characteristics to psychopathological comorbidities among adult patients with epilepsy.
A total of 262 participants (131 adult patient-caregiver pairs) were enrolled in this study. The Hamilton Rating Scale for Depression (HAM-D) and the Hamilton Rating Scale for Anxiety (HAM-A) were applied to evaluate the depression and anxiety status among adult patients with epilepsy and their caregivers, respectively. We collected caregivers’ anxiety and depression, patients’ sociodemographic characteristic data, and disease status as independent variables using stepwise multiple linear regression analysis that were correlated to the degree of anxiety and depression among these adult patients with epilepsy.
Among adult patients with epilepsy, 46 (35.11%) subjects showed anxiety symptoms (HAM-A scores > 6), and 48 (36.64%) had depression symptoms (HAM-D scores > 6). Caregivers’ anxiety levels and place of residence were significant independent predictors of both anxiety and depression levels among adult patients with epilepsy.
Adult patients with epilepsy are at a high risk of suffering from anxiety and depression. Caregivers’ anxiety and place of residence are definite independent predictors for anxiety and depression severity among adult patients with epilepsy. Therefore, clinicians should be careful in closely monitoring the psychological status of adult patients with epilepsy and their caregivers. Furthermore, the government and medical institutions should increase educational awareness about epilepsy and its cure, especially among adult patients with epilepsy who live in rural areas and consider offering a multidisciplinary management program to improve these patients' psychological status. This study was aimed to assess the prevalence of anxiety and depression and the possible contributions of the caregiver's anxiety and depression, disease status, and socio-demographic characteristics to psychopathological comorbidities among adult patients with epilepsy.OBJECTIVESThis study was aimed to assess the prevalence of anxiety and depression and the possible contributions of the caregiver's anxiety and depression, disease status, and socio-demographic characteristics to psychopathological comorbidities among adult patients with epilepsy.A total of 262 participants (131 adult patient-caregiver pairs) were enrolled in this study. The Hamilton Rating Scale for Depression (HAM-D) and the Hamilton Rating Scale for Anxiety (HAM-A) were applied to evaluate the depression and anxiety status among adult patients with epilepsy and their caregivers, respectively. We collected caregivers' anxiety and depression, patients' sociodemographic characteristic data, and disease status as independent variables using stepwise multiple linear regression analysis that were correlated to the degree of anxiety and depression among these adult patients with epilepsy.METHODSA total of 262 participants (131 adult patient-caregiver pairs) were enrolled in this study. The Hamilton Rating Scale for Depression (HAM-D) and the Hamilton Rating Scale for Anxiety (HAM-A) were applied to evaluate the depression and anxiety status among adult patients with epilepsy and their caregivers, respectively. We collected caregivers' anxiety and depression, patients' sociodemographic characteristic data, and disease status as independent variables using stepwise multiple linear regression analysis that were correlated to the degree of anxiety and depression among these adult patients with epilepsy.Among adult patients with epilepsy, 46 (35.11%) subjects showed anxiety symptoms (HAM-A scores > 6), and 48 (36.64%) had depression symptoms (HAM-D scores > 6). Caregivers' anxiety levels and place of residence were significant independent predictors of both anxiety and depression levels among adult patients with epilepsy.RESULTSAmong adult patients with epilepsy, 46 (35.11%) subjects showed anxiety symptoms (HAM-A scores > 6), and 48 (36.64%) had depression symptoms (HAM-D scores > 6). Caregivers' anxiety levels and place of residence were significant independent predictors of both anxiety and depression levels among adult patients with epilepsy.Adult patients with epilepsy are at a high risk of suffering from anxiety and depression. Caregivers' anxiety and place of residence are definite independent predictors for anxiety and depression severity among adult patients with epilepsy. Therefore, clinicians should be careful in closely monitoring the psychological status of adult patients with epilepsy and their caregivers. Furthermore, the government and medical institutions should increase educational awareness about epilepsy and its cure, especially among adult patients with epilepsy who live in rural areas and consider offering a multidisciplinary management program to improve these patients' psychological status.CONCLUSIONSAdult patients with epilepsy are at a high risk of suffering from anxiety and depression. Caregivers' anxiety and place of residence are definite independent predictors for anxiety and depression severity among adult patients with epilepsy. Therefore, clinicians should be careful in closely monitoring the psychological status of adult patients with epilepsy and their caregivers. Furthermore, the government and medical institutions should increase educational awareness about epilepsy and its cure, especially among adult patients with epilepsy who live in rural areas and consider offering a multidisciplinary management program to improve these patients' psychological status. This study was aimed to assess the prevalence of anxiety and depression and the possible contributions of the caregiver's anxiety and depression, disease status, and socio-demographic characteristics to psychopathological comorbidities among adult patients with epilepsy. A total of 262 participants (131 adult patient-caregiver pairs) were enrolled in this study. The Hamilton Rating Scale for Depression (HAM-D) and the Hamilton Rating Scale for Anxiety (HAM-A) were applied to evaluate the depression and anxiety status among adult patients with epilepsy and their caregivers, respectively. We collected caregivers' anxiety and depression, patients' sociodemographic characteristic data, and disease status as independent variables using stepwise multiple linear regression analysis that were correlated to the degree of anxiety and depression among these adult patients with epilepsy. Among adult patients with epilepsy, 46 (35.11%) subjects showed anxiety symptoms (HAM-A scores > 6), and 48 (36.64%) had depression symptoms (HAM-D scores > 6). Caregivers' anxiety levels and place of residence were significant independent predictors of both anxiety and depression levels among adult patients with epilepsy. Adult patients with epilepsy are at a high risk of suffering from anxiety and depression. Caregivers' anxiety and place of residence are definite independent predictors for anxiety and depression severity among adult patients with epilepsy. Therefore, clinicians should be careful in closely monitoring the psychological status of adult patients with epilepsy and their caregivers. Furthermore, the government and medical institutions should increase educational awareness about epilepsy and its cure, especially among adult patients with epilepsy who live in rural areas and consider offering a multidisciplinary management program to improve these patients' psychological status. |
| ArticleNumber | 108628 |
| Author | Zhu, Xue-rui Wang, Li-xia Zhao, Ting Han, Xiong Zhu, Zhi-rui |
| Author_xml | – sequence: 1 givenname: Xue-rui surname: Zhu fullname: Zhu, Xue-rui organization: Department of Neuroelectrophysiology, Zhengzhou Seventh People's Hospital, Henan Province, Zhengzhou 450003, China – sequence: 2 givenname: Zhi-rui surname: Zhu fullname: Zhu, Zhi-rui organization: Department of Cardiology, Zhengzhou Seventh People's Hospital, Henan Province, Zhengzhou 450003, China – sequence: 3 givenname: Li-xia surname: Wang fullname: Wang, Li-xia organization: Department of Neuroelectrophysiology, Zhengzhou Seventh People's Hospital, Henan Province, Zhengzhou 450003, China – sequence: 4 givenname: Ting surname: Zhao fullname: Zhao, Ting organization: Department of Neurology, Henan Provincial People’s Hospital, Zhengzhou University People’s Hospital, Zhengzhou 450003, China – sequence: 5 givenname: Xiong surname: Han fullname: Han, Xiong email: hanxiong7589@126.com organization: Department of Neurology, Henan Provincial People’s Hospital, Zhengzhou University People’s Hospital, Zhengzhou 450003, China |
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| CitedBy_id | crossref_primary_10_1016_j_brainres_2023_148662 crossref_primary_10_1360_SSV_2022_0194 crossref_primary_10_1007_s15016_022_9560_z crossref_primary_10_47793_hp_1349300 crossref_primary_10_3389_fpsyt_2023_1283983 crossref_primary_10_1016_j_seizure_2023_01_002 crossref_primary_10_1007_s00415_023_11792_1 crossref_primary_10_7759_cureus_56401 crossref_primary_10_1016_j_eplepsyres_2023_107146 crossref_primary_10_3390_ijerph19148636 crossref_primary_10_17826_cumj_1138971 crossref_primary_10_1523_ENEURO_0162_24_2024 |
| Cites_doi | 10.1111/epi.13769 10.1016/j.nbd.2014.10.021 10.1111/epi.13807 10.1016/S0140-6736(14)60456-6 10.1016/j.yebeh.2016.12.011 10.1186/s12991-018-0197-z 10.1016/S0140-6736(19)31425-4 10.1111/epi.16688 10.1002/jnr.23800 10.3389/fneur.2021.744377 10.1192/bjp.152.5.660 10.1038/ncomms14536 10.1016/j.seizure.2020.09.015 10.1097/MD.0000000000020647 10.1016/S0140-6736(12)61646-8 10.1016/S1474-4422(16)30400-8 10.1016/j.yebeh.2020.107256 10.1016/j.seizure.2020.05.026 10.1016/j.seizure.2019.02.014 10.1016/j.yebeh.2019.106653 10.1016/j.yebeh.2014.08.029 10.1136/jnnp.23.1.56 10.1111/j.2044-8341.1959.tb00467.x 10.1016/S1474-4422(19)30269-8 10.1016/j.yebeh.2018.11.015 10.1111/epi.12550 10.1038/s41583-019-0126-4 10.1016/S1474-4422(19)30042-0 10.1176/jnp.17.2.172 10.1016/j.seizure.2018.03.012 10.1016/S0140-6736(12)61381-6 10.1111/j.1528-1167.2009.02481.x 10.1038/ng.2727 10.1016/j.coph.2015.11.002 10.1016/j.yebeh.2021.108060 10.1016/j.yebeh.2011.01.013 10.1111/j.1528-1167.2011.03121.x 10.1111/epi.13817 10.1016/j.yebeh.2019.07.001 |
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| References | Carvill, Regan, Yendle, O'Roak, Lozovaya, Bruneau (b0075) 2013; 45 Ellis, Petrovski, Berkovic (b0065) 2020; 19 Braga, Mifsud, D’Souza, Clarke, Honein, Tovuudorj (b0110) 2020; 103 Jennum, Debes, Ibsen, Kjellberg (b0105) 2021; 114 Iori, Frigerio, Vezzani (b0030) 2016; 26 Tantik Pak, Sengul, Sengul, Mail Gurkan (b0125) 2021; 121 Mukhtar (b0025) 2020; 82 Hamilton (b0145) 1959; 32 Chaka, Awoke, Yohannis, Ayano, Tareke, Abate (b0185) 2018; 17 Pham, Sauro, Patten, Wiebe, Fiest, Bulloch (b0190) 2017; 58 Thurman, Beghi, Begley, Berg, Buchhalter, Ding (b0020) 2011; 52 Kuehn (b0095) 2019; 322 Kim, Kim, Jeon, Kim, Lee (b0130) 2020; 80 Jones, Hermann, Barry, Gilliam, Kanner, Meador (b0170) 2005; 17 Li, Chen, Zhu, Wang, Xu, Tan (b0175) 2019; 66 Yang, Hao, Mao, Xu, Zhao, Zhang (b0210) 2020; 99 Scott, Sharpe, Hunt, Gandy (b0165) 2017; 58 Asadi-Pooya, Kanemoto, Kwon, Taniguchi, Dong, Chinvarun (b0180) 2018; 57 Ngugi, Bottomley, Kleinschmidt, Sander, Newton (b0015) 2010; 51 Eugen, Patrick, Byungin, Amitabh (b0090) 2018 Hamilton (b0150) 1960; 23 Langenbruch, Bleß, Schulte‐Mecklenbeck, Sundermann, Brix, Elger (b0035) 2020; 61 Koeleman (b0070) 2017; 16 Fisher, Acevedo, Arzimanoglou, Bogacz, Cross, Elger (b0140) 2014; 55 Zheng, Zhao, Phillips, Liu, Cai, Sun (b0155) 1988; 152 Zhou, Ding, Deel, Ferrick, Emeson, Gallagher (b0050) 2015; 73 Uchida, Lossin, Ihara, Deshimaru, Yanagawa, Koyama (b0045) 2017; 58 Mula, Iudice, La Neve, Mazza, Mazza, Cantello (b0160) 2014; 41 Moshé, Perucca, Ryvlin, Tomson (b0080) 2015; 385 Epilepsy prevention: an urgent global unmet need. Lancet. 2019, 393 (10191): 2564. Bedner, Steinhäuser (b0060) 2016; 94 Puka, Widjaja, Smith (b0200) 2017; 67 Zhu, Zhao, Gu, Gao, Wang, Zhao (b0205) 2019; 90 Puka, Widjaja, Smith (b0135) 2017; 67 Elliott, Charyton, Sprangers, Lu, Moore (b0115) 2011; 20 Forthoffer, Tarrada, Brissart, Maillard, Hingray (b0120) 2021; 12 Wanted: a global campaign against epilepsy. Lancet. 2012, 380 (9848):1121. Zapata, Moretto, Hannan, Murru, Longatti, Mazza (b0040) 2017; 8 Newton, Garcia (b0085) 2012; 380 Zheng, Ding, Guo, Chen, Wang, Zheng (b0195) 2019; 100 Hauser (b0100) 2019; 18 Patel, Tewari, Chaunsali, Sontheimer (b0055) 2019; 20 Koeleman (10.1016/j.yebeh.2022.108628_b0070) 2017; 16 Kim (10.1016/j.yebeh.2022.108628_b0130) 2020; 80 Jennum (10.1016/j.yebeh.2022.108628_b0105) 2021; 114 Zhou (10.1016/j.yebeh.2022.108628_b0050) 2015; 73 Zapata (10.1016/j.yebeh.2022.108628_b0040) 2017; 8 Langenbruch (10.1016/j.yebeh.2022.108628_b0035) 2020; 61 Bedner (10.1016/j.yebeh.2022.108628_b0060) 2016; 94 Eugen (10.1016/j.yebeh.2022.108628_b0090) 2018 Hauser (10.1016/j.yebeh.2022.108628_b0100) 2019; 18 Uchida (10.1016/j.yebeh.2022.108628_b0045) 2017; 58 Thurman (10.1016/j.yebeh.2022.108628_b0020) 2011; 52 Fisher (10.1016/j.yebeh.2022.108628_b0140) 2014; 55 Carvill (10.1016/j.yebeh.2022.108628_b0075) 2013; 45 Braga (10.1016/j.yebeh.2022.108628_b0110) 2020; 103 Li (10.1016/j.yebeh.2022.108628_b0175) 2019; 66 Zheng (10.1016/j.yebeh.2022.108628_b0195) 2019; 100 Elliott (10.1016/j.yebeh.2022.108628_b0115) 2011; 20 Puka (10.1016/j.yebeh.2022.108628_b0135) 2017; 67 10.1016/j.yebeh.2022.108628_b0010 Patel (10.1016/j.yebeh.2022.108628_b0055) 2019; 20 Chaka (10.1016/j.yebeh.2022.108628_b0185) 2018; 17 Yang (10.1016/j.yebeh.2022.108628_b0210) 2020; 99 Forthoffer (10.1016/j.yebeh.2022.108628_b0120) 2021; 12 Iori (10.1016/j.yebeh.2022.108628_b0030) 2016; 26 Asadi-Pooya (10.1016/j.yebeh.2022.108628_b0180) 2018; 57 Pham (10.1016/j.yebeh.2022.108628_b0190) 2017; 58 Jones (10.1016/j.yebeh.2022.108628_b0170) 2005; 17 Zheng (10.1016/j.yebeh.2022.108628_b0155) 1988; 152 Puka (10.1016/j.yebeh.2022.108628_b0200) 2017; 67 Newton (10.1016/j.yebeh.2022.108628_b0085) 2012; 380 Tantik Pak (10.1016/j.yebeh.2022.108628_b0125) 2021; 121 10.1016/j.yebeh.2022.108628_b0005 Mukhtar (10.1016/j.yebeh.2022.108628_b0025) 2020; 82 Scott (10.1016/j.yebeh.2022.108628_b0165) 2017; 58 Mula (10.1016/j.yebeh.2022.108628_b0160) 2014; 41 Kuehn (10.1016/j.yebeh.2022.108628_b0095) 2019; 322 Hamilton (10.1016/j.yebeh.2022.108628_b0145) 1959; 32 Zhu (10.1016/j.yebeh.2022.108628_b0205) 2019; 90 Hamilton (10.1016/j.yebeh.2022.108628_b0150) 1960; 23 Ngugi (10.1016/j.yebeh.2022.108628_b0015) 2010; 51 Ellis (10.1016/j.yebeh.2022.108628_b0065) 2020; 19 Moshé (10.1016/j.yebeh.2022.108628_b0080) 2015; 385 |
| References_xml | – volume: 16 start-page: 101 year: 2017 end-page: 102 ident: b0070 article-title: Genetics of common forms of epilepsy publication-title: Lancet Neurol – volume: 20 start-page: 533 year: 2011 end-page: 538 ident: b0115 article-title: The impact of marriage and social support on persons with active epilepsy publication-title: Epilepsy Behav – volume: 17 year: 2018 ident: b0185 article-title: Determinants of depression among people with epilepsy in Central Ethiopia publication-title: Ann Gen Psychiatry – volume: 32 start-page: 50 year: 1959 end-page: 55 ident: b0145 article-title: The assessment of anxiety states by rating publication-title: Br J Med Psychol – volume: 152 start-page: 660 year: 1988 end-page: 664 ident: b0155 article-title: Validity and reliability of the Chinese Hamilton Depression Rating Scale publication-title: Br J Psychiatry – volume: 67 start-page: 45 year: 2017 end-page: 50 ident: b0135 article-title: The influence of patient, caregiver, and family factors on symptoms of anxiety and depression in children and adolescents with intractable epilepsy publication-title: Epilepsy Behav – volume: 23 start-page: 56 year: 1960 end-page: 62 ident: b0150 article-title: A rating scale for depression publication-title: J Neurol Neurosurg Psychiatry – volume: 114 start-page: 107256 year: 2021 ident: b0105 article-title: Long-term employment, education, and healthcare costs of childhood and adolescent onset of epilepsy publication-title: Epilepsy Behav – volume: 12 start-page: 744377 year: 2021 ident: b0120 article-title: Anxiety and depression in newly diagnosed epilepsy a matter of psychological history? publication-title: Front Neurol – volume: 82 start-page: 65 year: 2020 end-page: 79 ident: b0025 article-title: Inflammatory and immune mechanisms underlying epileptogenesis and epilepsy: from pathogenesis to treatment publication-title: Seizure – volume: 66 start-page: 86 year: 2019 end-page: 92 ident: b0175 article-title: Depression in people with epilepsy in West China: status, risk factors and treatment gap publication-title: Seizure – volume: 58 start-page: 1430 year: 2017 end-page: 1439 ident: b0045 article-title: Abnormal γ-aminobutyric acid neurotransmission in a Kcnq2 model of early onset epilepsy publication-title: Epilepsia – volume: 73 start-page: 407 year: 2015 end-page: 417 ident: b0050 article-title: Altered intrathalamic GABAA neurotransmission in a mouse model of a human genetic absence epilepsy syndrome publication-title: Neurobiol Dis – volume: 90 start-page: 132 year: 2019 end-page: 136 ident: b0205 article-title: High risk of anxiety and depression in caregivers of adult patients with epilepsy and its negative impact on patients' quality of life publication-title: Epilepsy Behav – volume: 17 start-page: 172 year: 2005 end-page: 179 ident: b0170 article-title: Clinical assessment of Axis I psychiatric morbidity in chronic epilepsy: a multicenter investigation publication-title: Neuropsychiatry Clin Neurosci – volume: 100 start-page: 106400 year: 2019 ident: b0195 article-title: Multidisciplinary management improves anxiety, depression, medication adherence, and quality of life among patients with epilepsy in eastern China: a prospective study publication-title: Epilepsy Behav – volume: 57 start-page: 45 year: 2018 end-page: 49 ident: b0180 article-title: Depression in people with epilepsy: How much do Asian colleagues acknowledge it? publication-title: Seizure – volume: 26 start-page: 118 year: 2016 end-page: 123 ident: b0030 article-title: Modulation of neuronal excitability by immune mediators in epilepsy publication-title: Curr Opin Pharmacol – volume: 94 start-page: 779 year: 2016 end-page: 780 ident: b0060 article-title: Neuron-glia interaction in epilepsy publication-title: J Neurosci Res – volume: 45 start-page: 1073 year: 2013 end-page: 1076 ident: b0075 article-title: GRIN2A mutations cause epilepsy-aphasia spectrum disorders publication-title: Nat Genet – volume: 61 start-page: e153 year: 2020 end-page: e158 ident: b0035 article-title: Blood and cerebrospinal fluid immune cell profiles in patients with temporal lobe epilepsy of different etiologies publication-title: Epilepsia – volume: 380 start-page: 1193 year: 2012 end-page: 1201 ident: b0085 article-title: Epilepsy in poor regions of the world publication-title: Lancet – volume: 41 start-page: 122 year: 2014 end-page: 125 ident: b0160 article-title: Validation of the Hamilton Rating Scale for Depression in adults with epilepsy publication-title: Epilepsy Behav – reference: Epilepsy prevention: an urgent global unmet need. Lancet. 2019, 393 (10191): 2564. – volume: 58 start-page: 107 year: 2017 end-page: 110 ident: b0190 article-title: The prevalence of anxiety and associated factors in persons with epilepsy publication-title: Epilepsia – volume: 99 start-page: 20647 year: 2020 ident: b0210 article-title: Depression in children with epilepsy from western China: a cross-sectional survey publication-title: Medicine (Baltimore) – volume: 58 start-page: 973 year: 2017 end-page: 982 ident: b0165 article-title: Anxiety and depressive disorders in people with epilepsy: a meta-analysis publication-title: Epilepsia – volume: 8 start-page: 14536 year: 2017 ident: b0040 article-title: Epilepsy and intellectual disability linked protein Shrm4 interaction with GABABRs shapes inhibitory neurotransmission publication-title: Nat Commun – volume: 20 start-page: 282 year: 2019 end-page: 297 ident: b0055 article-title: Neuron-glia interactions in the pathophysiology of epilepsy publication-title: Nat Rev Neurosci – volume: 52 start-page: 2 year: 2011 end-page: 26 ident: b0020 article-title: Standards for epidemiologic studies and surveillance of epilepsy publication-title: Epilepsia – volume: 80 start-page: 86 year: 2020 end-page: 91 ident: b0130 article-title: Clinical factors associated with suicide risk independent of depression in persons with epilepsy publication-title: Seizure – volume: 103 start-page: 106653 year: 2020 ident: b0110 article-title: Education and epilepsy: examples of good practice and cooperation. Report of the IBE Commission on Education publication-title: Epilepsy Behav – year: 2018 ident: b0090 article-title: Epilepsy in Asia: disease burden, management barriers, and challenges publication-title: Epilepsia – volume: 19 start-page: 93 year: 2020 end-page: 100 ident: b0065 article-title: Epilepsy genetics: clinical impacts and biological insights publication-title: Lancet Neurol – volume: 18 start-page: 322 year: 2019 end-page: 324 ident: b0100 article-title: An unparalleled assessment of the global burden of epilepsy publication-title: Lancet Neurol – volume: 385 start-page: 884 year: 2015 end-page: 898 ident: b0080 article-title: Epilepsy: new advances publication-title: Lancet – reference: Wanted: a global campaign against epilepsy. Lancet. 2012, 380 (9848):1121. – volume: 51 start-page: 883 year: 2010 end-page: 890 ident: b0015 article-title: Estimation of the burden of active and life-time epilepsy: a meta-analytic approach publication-title: Epilepsia – volume: 322 start-page: 603 year: 2019 ident: b0095 article-title: Fighting epilepsy stigma publication-title: JAMA – volume: 67 start-page: 45 year: 2017 end-page: 50 ident: b0200 article-title: The influence of patient, caregiver, and family factors on symptoms of anxiety and depression in children and adolescents with intractable epilepsy publication-title: Epilepsy Behav – volume: 121 start-page: 108060 year: 2021 ident: b0125 article-title: Social phobia and its relationship with perceived epilepsy-associated stigma in patients with epilepsy publication-title: Epilepsy Behav – volume: 55 start-page: 475 year: 2014 end-page: 482 ident: b0140 article-title: ILAE official report: a practical clinical definition of epilepsy publication-title: Epilepsia – volume: 58 start-page: 973 issue: 6 year: 2017 ident: 10.1016/j.yebeh.2022.108628_b0165 article-title: Anxiety and depressive disorders in people with epilepsy: a meta-analysis publication-title: Epilepsia doi: 10.1111/epi.13769 – volume: 73 start-page: 407 year: 2015 ident: 10.1016/j.yebeh.2022.108628_b0050 article-title: Altered intrathalamic GABAA neurotransmission in a mouse model of a human genetic absence epilepsy syndrome publication-title: Neurobiol Dis doi: 10.1016/j.nbd.2014.10.021 – volume: 58 start-page: 1430 issue: 8 year: 2017 ident: 10.1016/j.yebeh.2022.108628_b0045 article-title: Abnormal γ-aminobutyric acid neurotransmission in a Kcnq2 model of early onset epilepsy publication-title: Epilepsia doi: 10.1111/epi.13807 – volume: 385 start-page: 884 issue: 9971 year: 2015 ident: 10.1016/j.yebeh.2022.108628_b0080 article-title: Epilepsy: new advances publication-title: Lancet doi: 10.1016/S0140-6736(14)60456-6 – volume: 67 start-page: 45 year: 2017 ident: 10.1016/j.yebeh.2022.108628_b0135 article-title: The influence of patient, caregiver, and family factors on symptoms of anxiety and depression in children and adolescents with intractable epilepsy publication-title: Epilepsy Behav doi: 10.1016/j.yebeh.2016.12.011 – volume: 17 year: 2018 ident: 10.1016/j.yebeh.2022.108628_b0185 article-title: Determinants of depression among people with epilepsy in Central Ethiopia publication-title: Ann Gen Psychiatry doi: 10.1186/s12991-018-0197-z – ident: 10.1016/j.yebeh.2022.108628_b0005 doi: 10.1016/S0140-6736(19)31425-4 – volume: 61 start-page: e153 issue: 10 year: 2020 ident: 10.1016/j.yebeh.2022.108628_b0035 article-title: Blood and cerebrospinal fluid immune cell profiles in patients with temporal lobe epilepsy of different etiologies publication-title: Epilepsia doi: 10.1111/epi.16688 – volume: 94 start-page: 779 issue: 9 year: 2016 ident: 10.1016/j.yebeh.2022.108628_b0060 article-title: Neuron-glia interaction in epilepsy publication-title: J Neurosci Res doi: 10.1002/jnr.23800 – volume: 12 start-page: 744377 year: 2021 ident: 10.1016/j.yebeh.2022.108628_b0120 article-title: Anxiety and depression in newly diagnosed epilepsy a matter of psychological history? publication-title: Front Neurol doi: 10.3389/fneur.2021.744377 – volume: 152 start-page: 660 issue: 5 year: 1988 ident: 10.1016/j.yebeh.2022.108628_b0155 article-title: Validity and reliability of the Chinese Hamilton Depression Rating Scale publication-title: Br J Psychiatry doi: 10.1192/bjp.152.5.660 – volume: 8 start-page: 14536 year: 2017 ident: 10.1016/j.yebeh.2022.108628_b0040 article-title: Epilepsy and intellectual disability linked protein Shrm4 interaction with GABABRs shapes inhibitory neurotransmission publication-title: Nat Commun doi: 10.1038/ncomms14536 – volume: 82 start-page: 65 year: 2020 ident: 10.1016/j.yebeh.2022.108628_b0025 article-title: Inflammatory and immune mechanisms underlying epileptogenesis and epilepsy: from pathogenesis to treatment publication-title: Seizure doi: 10.1016/j.seizure.2020.09.015 – volume: 99 start-page: 20647 issue: 24 year: 2020 ident: 10.1016/j.yebeh.2022.108628_b0210 article-title: Depression in children with epilepsy from western China: a cross-sectional survey publication-title: Medicine (Baltimore) doi: 10.1097/MD.0000000000020647 – ident: 10.1016/j.yebeh.2022.108628_b0010 doi: 10.1016/S0140-6736(12)61646-8 – volume: 16 start-page: 101 issue: 2 year: 2017 ident: 10.1016/j.yebeh.2022.108628_b0070 article-title: Genetics of common forms of epilepsy publication-title: Lancet Neurol doi: 10.1016/S1474-4422(16)30400-8 – volume: 114 start-page: 107256 issue: Pt A year: 2021 ident: 10.1016/j.yebeh.2022.108628_b0105 article-title: Long-term employment, education, and healthcare costs of childhood and adolescent onset of epilepsy publication-title: Epilepsy Behav doi: 10.1016/j.yebeh.2020.107256 – volume: 80 start-page: 86 year: 2020 ident: 10.1016/j.yebeh.2022.108628_b0130 article-title: Clinical factors associated with suicide risk independent of depression in persons with epilepsy publication-title: Seizure doi: 10.1016/j.seizure.2020.05.026 – volume: 66 start-page: 86 year: 2019 ident: 10.1016/j.yebeh.2022.108628_b0175 article-title: Depression in people with epilepsy in West China: status, risk factors and treatment gap publication-title: Seizure doi: 10.1016/j.seizure.2019.02.014 – volume: 103 start-page: 106653 year: 2020 ident: 10.1016/j.yebeh.2022.108628_b0110 article-title: Education and epilepsy: examples of good practice and cooperation. Report of the IBE Commission on Education publication-title: Epilepsy Behav doi: 10.1016/j.yebeh.2019.106653 – volume: 41 start-page: 122 year: 2014 ident: 10.1016/j.yebeh.2022.108628_b0160 article-title: Validation of the Hamilton Rating Scale for Depression in adults with epilepsy publication-title: Epilepsy Behav doi: 10.1016/j.yebeh.2014.08.029 – volume: 23 start-page: 56 issue: 1 year: 1960 ident: 10.1016/j.yebeh.2022.108628_b0150 article-title: A rating scale for depression publication-title: J Neurol Neurosurg Psychiatry doi: 10.1136/jnnp.23.1.56 – year: 2018 ident: 10.1016/j.yebeh.2022.108628_b0090 article-title: Epilepsy in Asia: disease burden, management barriers, and challenges publication-title: Epilepsia – volume: 32 start-page: 50 issue: 1 year: 1959 ident: 10.1016/j.yebeh.2022.108628_b0145 article-title: The assessment of anxiety states by rating publication-title: Br J Med Psychol doi: 10.1111/j.2044-8341.1959.tb00467.x – volume: 19 start-page: 93 issue: 1 year: 2020 ident: 10.1016/j.yebeh.2022.108628_b0065 article-title: Epilepsy genetics: clinical impacts and biological insights publication-title: Lancet Neurol doi: 10.1016/S1474-4422(19)30269-8 – volume: 322 start-page: 603 issue: 7 year: 2019 ident: 10.1016/j.yebeh.2022.108628_b0095 article-title: Fighting epilepsy stigma publication-title: JAMA – volume: 90 start-page: 132 year: 2019 ident: 10.1016/j.yebeh.2022.108628_b0205 article-title: High risk of anxiety and depression in caregivers of adult patients with epilepsy and its negative impact on patients' quality of life publication-title: Epilepsy Behav doi: 10.1016/j.yebeh.2018.11.015 – volume: 55 start-page: 475 issue: 4 year: 2014 ident: 10.1016/j.yebeh.2022.108628_b0140 article-title: ILAE official report: a practical clinical definition of epilepsy publication-title: Epilepsia doi: 10.1111/epi.12550 – volume: 20 start-page: 282 issue: 5 year: 2019 ident: 10.1016/j.yebeh.2022.108628_b0055 article-title: Neuron-glia interactions in the pathophysiology of epilepsy publication-title: Nat Rev Neurosci doi: 10.1038/s41583-019-0126-4 – volume: 18 start-page: 322 issue: 4 year: 2019 ident: 10.1016/j.yebeh.2022.108628_b0100 article-title: An unparalleled assessment of the global burden of epilepsy publication-title: Lancet Neurol doi: 10.1016/S1474-4422(19)30042-0 – volume: 17 start-page: 172 year: 2005 ident: 10.1016/j.yebeh.2022.108628_b0170 article-title: Clinical assessment of Axis I psychiatric morbidity in chronic epilepsy: a multicenter investigation publication-title: Neuropsychiatry Clin Neurosci doi: 10.1176/jnp.17.2.172 – volume: 57 start-page: 45 year: 2018 ident: 10.1016/j.yebeh.2022.108628_b0180 article-title: Depression in people with epilepsy: How much do Asian colleagues acknowledge it? publication-title: Seizure doi: 10.1016/j.seizure.2018.03.012 – volume: 380 start-page: 1193 issue: 9848 year: 2012 ident: 10.1016/j.yebeh.2022.108628_b0085 article-title: Epilepsy in poor regions of the world publication-title: Lancet doi: 10.1016/S0140-6736(12)61381-6 – volume: 51 start-page: 883 year: 2010 ident: 10.1016/j.yebeh.2022.108628_b0015 article-title: Estimation of the burden of active and life-time epilepsy: a meta-analytic approach publication-title: Epilepsia doi: 10.1111/j.1528-1167.2009.02481.x – volume: 45 start-page: 1073 issue: 9 year: 2013 ident: 10.1016/j.yebeh.2022.108628_b0075 article-title: GRIN2A mutations cause epilepsy-aphasia spectrum disorders publication-title: Nat Genet doi: 10.1038/ng.2727 – volume: 67 start-page: 45 year: 2017 ident: 10.1016/j.yebeh.2022.108628_b0200 article-title: The influence of patient, caregiver, and family factors on symptoms of anxiety and depression in children and adolescents with intractable epilepsy publication-title: Epilepsy Behav doi: 10.1016/j.yebeh.2016.12.011 – volume: 26 start-page: 118 year: 2016 ident: 10.1016/j.yebeh.2022.108628_b0030 article-title: Modulation of neuronal excitability by immune mediators in epilepsy publication-title: Curr Opin Pharmacol doi: 10.1016/j.coph.2015.11.002 – volume: 121 start-page: 108060 issue: Pt A year: 2021 ident: 10.1016/j.yebeh.2022.108628_b0125 article-title: Social phobia and its relationship with perceived epilepsy-associated stigma in patients with epilepsy publication-title: Epilepsy Behav doi: 10.1016/j.yebeh.2021.108060 – volume: 20 start-page: 533 year: 2011 ident: 10.1016/j.yebeh.2022.108628_b0115 article-title: The impact of marriage and social support on persons with active epilepsy publication-title: Epilepsy Behav doi: 10.1016/j.yebeh.2011.01.013 – volume: 52 start-page: 2 issue: suppl 7 year: 2011 ident: 10.1016/j.yebeh.2022.108628_b0020 article-title: Standards for epidemiologic studies and surveillance of epilepsy publication-title: Epilepsia doi: 10.1111/j.1528-1167.2011.03121.x – volume: 58 start-page: 107 issue: 8 year: 2017 ident: 10.1016/j.yebeh.2022.108628_b0190 article-title: The prevalence of anxiety and associated factors in persons with epilepsy publication-title: Epilepsia doi: 10.1111/epi.13817 – volume: 100 start-page: 106400 year: 2019 ident: 10.1016/j.yebeh.2022.108628_b0195 article-title: Multidisciplinary management improves anxiety, depression, medication adherence, and quality of life among patients with epilepsy in eastern China: a prospective study publication-title: Epilepsy Behav doi: 10.1016/j.yebeh.2019.07.001 |
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| SubjectTerms | Adult Anxiety Anxiety - epidemiology Anxiety - etiology Anxiety - psychology Caregivers Caregivers - psychology Cross-Sectional Studies Depression Depression - epidemiology Depression - etiology Depression - psychology Epilepsy Epilepsy - complications Epilepsy - epidemiology Humans Place of residence Prevalence Risk Factors |
| Title | Prevalence and risk factors for depression and anxiety in adult patients with epilepsy: Caregivers’ anxiety and place of residence do mater |
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