Targeting PIM1-Mediated Metabolism in Myeloid Suppressor Cells to Treat Cancer - Xin, Gang; Chen, Yao; Topchyan, Paytsar; Kasmani, Moujtaba Y; Burns, Robert; Volberding, Peter J; Wu, Xiaopeng; Cohn, Alexandra; Chen, Yiliang; Lin, Chien-Wei; Ho, Ping-Chih; Silverstein, Roy; et al. (Cancer immunology research, 2021)
Keywords: Animals; B7-H1 Antigen - drug effects; B7-H1 Antigen - immunology; B7-H1 Antigen - metabolism; Biphenyl Compounds - pharmacology; CD8-Positive T-Lymphocytes - immunology; Cell Line, Tumor; Drug Resistance, Neoplasm; Female; Humans; Immune Checkpoint Inhibitors - pharmacology; Immunotherapy - methods; Male; Mice; Mice, Inbred C57BL; Myeloid-Derived Suppressor Cells - immunology; Myeloid-Derived Suppressor Cells - metabolism; Neoplasms, Experimental - metabolism; Proto-Oncogene Proteins c-pim-1 - genetics; Proto-Oncogene Proteins c-pim-1 - metabolism; Thiazolidines - pharmacology; Tumor Microenvironment - immunology