Safety and feasibility of volumetric laser endomicroscopy in patients with Barrett’s esophagus (with videos)

• Published in: Gastrointestinal endoscopy Vol. 82; no. 4; pp. 631 - 640
• Main Authors: Wolfsen, Herbert C., MD, Sharma, Prateek, MD, Wallace, Michael B., MD, MPH, Leggett, Cadman, MD, Tearney, Guillermo, MD, PhD, Wang, Kenneth K., MD
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.10.2015
• Subjects: Adult; Aged; Aged, 80 and over; Barrett Esophagus - pathology; Barrett Esophagus - surgery; Biopsy; Esophagoscopy - instrumentation; Esophagoscopy - methods; Esophagus - pathology; Esophagus - surgery; Feasibility Studies; Female; Gastroenterology and Hepatology; Humans; Male; Middle Aged; Mucous Membrane - pathology; Mucous Membrane - surgery; Patient Safety; Prospective Studies; Tomography, Optical Coherence - instrumentation; Tomography, Optical Coherence - methods; OCT; volumetric laser endomicroscopy; BE; optical coherence tomography; Barrett's esophagus; confocal laser endomicroscopy; OFDI; CLE; optical frequency domain imaging; VLE

Background Volumetric laser endomicroscopy (VLE) produces high-resolution, cross-sectional surface, and subsurface images for detecting neoplasia, targeting biopsies, and guiding real-time treatment. Objective To evaluate the safety and feasibility of the Nvision VLE system. Design Prospective, mult...