Dominant effects of the Huntington's disease HTT CAG repeat length are captured in gene-expression data sets by a continuous analysis mathematical modeling strategy - Lee, Jong-Min; Galkina, Ekaterina I.; Levantovsky, Rachel M.; Fossale, Elisa; Anne Anderson, Mary; Gillis, Tammy; Srinidhi Mysore, Jayalakshmi; Coser, Kathryn R.; Shioda, Toshi; Zhang, Bin; Furia, Matthew D.; Derry, Jonathan; et al. (Human molecular genetics, 2013)
Keywords: Age of Onset; Alleles; Cell Line; Cerebellum - metabolism; Female; Gene Expression; Gene Expression Regulation; Humans; Huntingtin Protein; Huntington Disease - diagnosis; Huntington Disease - genetics; Huntington Disease - metabolism; Male; Models, Genetic; Nerve Tissue Proteins - genetics; Polymorphism, Genetic; Reproducibility of Results; Transcriptome; Trinucleotide Repeats - genetics