IL15 Enhances CAR-T Cell Antitumor Activity by Reducing mTORC1 Activity and Preserving Their Stem Cell Memory Phenotype - Alizadeh, Darya; Wong, Robyn A; Yang, Xin; Wang, Dongrui; Pecoraro, Joseph R; Kuo, Cheng-Fu; Aguilar, Brenda; Qi, Yue; Ann, David K; Starr, Renate; Urak, Ryan; Wang, Xiuli; et al. (Cancer immunology research, 2019)
Keywords: Animals; Cell Line, Tumor; Humans; Immunologic Memory; Immunotherapy, Adoptive; Interleukin-15 - immunology; Mechanistic Target of Rapamycin Complex 1 - immunology; Mice; Neoplasms - immunology; Neoplasms - therapy; Phenotype; Stem Cells - immunology; T-Lymphocytes - immunology; T-Lymphocytes - transplantation