Bioequivalence revisited: influence of age and sex on CYP enzymes - Bebia, Zourab; Buch, Shama C; Wilson, John W; Frye, Reginald F; Romkes, Marjorie; Cecchetti, Alfred; Chaves-Gnecco, Diego; Branch, Robert A (Clinical pharmacology and therapeutics, 2004)
Keywords: Adolescent; Adult; Aged; Aged, 80 and over; Aging - metabolism; Algorithms; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System - genetics; Cytochrome P-450 Enzyme System - metabolism; Female; Genotype; Humans; Isoenzymes - genetics; Isoenzymes - metabolism; Male; Middle Aged; Models, Statistical; Phenotype; Sex Characteristics; Therapeutic Equivalency