Intravenous Lidocaine Does Not Improve Neurologic Outcomes after Cardiac Surgery: A Randomized Controlled Trial - Klinger, Rebecca Y.; Cooter, Mary; Bisanar, Tiffany; Terrando, Niccolò; Berger, Miles; Podgoreanu, Mihai V.; Stafford-Smith, Mark; Newman, Mark F.; Mathew, Joseph P.; Blumenthal, James A.; Karhausen, Jorn A.; Kertai, Miklos D.; et al. (Anesthesiology (Philadelphia), 2019)
Keywords: Administration, Intravenous; Aged; Anesthetics, Local - administration & dosage; Anesthetics, Local - adverse effects; Cardiac Surgical Procedures - adverse effects; Cardiac Surgical Procedures - trends; Double-Blind Method; Female; Follow-Up Studies; Humans; Lidocaine - administration & dosage; Lidocaine - adverse effects; Male; Mental Status and Dementia Tests; Middle Aged; Neurocognitive Disorders - chemically induced; Neurocognitive Disorders - diagnosis; Neurocognitive Disorders - etiology; Postoperative Cognitive Complications - chemically induced; Postoperative Cognitive Complications - diagnosis; Postoperative Cognitive Complications - etiology; Prospective Studies; Treatment Outcome