Grading Clear Cell Renal Cell Carcinoma Grade Using Diffusion Relaxation Correlated MR Spectroscopic Imaging

• Published in: Journal of magnetic resonance imaging Vol. 59; no. 2; pp. 699 - 710
• Main Authors: Dai, Yongming, Hu, Wentao, Wu, Guangyu, Wu, Dongmei, Zhu, Mengying, Luo, Yuansheng, Wang, Jieying, Zhou, Yan, Hu, Peng
• Format: Journal Article
• Language: English
• Published: Hoboken, USA John Wiley & Sons, Inc 01.02.2024; Wiley Subscription Services, Inc
• Subjects: Aged; Biopsy; Carcinoma, Renal Cell - diagnostic imaging; Carcinoma, Renal Cell - pathology; clear cell renal cell carcinoma; Clear cell-type renal cell carcinoma; Correlation; Diffusion coefficient; Diffusion Magnetic Resonance Imaging - methods; diffusion weighted imaging; Field strength; Histopathology; Humans; Kidney cancer; Kidney Neoplasms - diagnostic imaging; Kidney Neoplasms - pathology; Magnetic Resonance Imaging; Male; Medical imaging; Middle Aged; multidimensional correlation MRI; Neoplasm Grading; Performance assessment; Prospective Studies; Regression analysis; Retrospective Studies; Segmentation; Solid tumors; Statistical analysis; Statistical tests; T2 relaxation time; tumor heterogeneity; Tumors; Variance analysis; clear cell renal cell carcinoma; diffusion weighted imaging; T2 relaxation time; multidimensional correlation MRI; tumor heterogeneity

Background Clear cell renal cell carcinoma (ccRCC) is the most common subtype of RCC, and accurate grading is crucial for prognosis and treatment selection. Biopsy is the reference standard for grading, but MRI methods can improve and complement the grading procedure. Purpose Assess the performance...