A simple chip free-flow electrophoresis for monosaccharide sensing via supermolecule interaction of boronic acid functionalized quencher and fluorescent dye

Here, a simple micro free‐flow electrophoresis (μFFE) was developed for fluorescence sensing of monosaccharide via supermolecule interaction of synthesized boronic acid functionalized benzyl viologen (ο‐BBV) and fluorescent dye. The μFFE contained two open electrode cavities and an ion‐exchange memb...

Full description

Saved in:

Bibliographic Details
Published in	Electrophoresis Vol. 34; no. 15; pp. 2185 - 2192
Main Authors	Yin, Xiao-Yang, Dong, Jing-Yu, Wang, Hou-Yu, Li, Si, Fan, Liu-Yin, Cao, Cheng-Xi
Format	Journal Article
Language	English
Published	Germany Blackwell Publishing Ltd 01.08.2013
Subjects	Benzyl Viologen - chemistry Boronic Acids - chemistry Chambers Detection Dyes Electrodes Electrophoresis Electrophoresis - instrumentation Electrophoresis - methods Fluorescent Dyes - chemistry Glycosuria - urine Humans Membranes Micro free-flow electrophoresis Microtechnology - instrumentation Monosaccharide Monosaccharides Monosaccharides - analysis Monosaccharides - chemistry Monosaccharides - urine Reusable Spectrometry, Fluorescence - methods Supermolecule interaction Micro free-flow electrophoresis Supermolecule interaction Monosaccharide
Online Access	Get full text

Cover

Loading…

Abstract	Here, a simple micro free‐flow electrophoresis (μFFE) was developed for fluorescence sensing of monosaccharide via supermolecule interaction of synthesized boronic acid functionalized benzyl viologen (ο‐BBV) and fluorescent dye. The μFFE contained two open electrode cavities and an ion‐exchange membrane was sandwiched between two polymethylmethacrylate plates. The experiments demonstrated the following merits of developed μFFE: (i) up to 90.5% of voltage efficiency due to high conductivity of ion‐exchange membrane; (ii) a strong ability against influence of bubble produced in two electrodes due to open design of electrode cavities; and (iii) reusable and washable separation chamber (45 mm × 17 mm × 100 μm, 77 μL) avoiding the discard of μFFE due to blockage of solute precipitation in chamber. Remarkably, the μFFE was first designed for the sensing of monosaccharide via the supermolecule interaction of synthesized ο‐BBV, fluorescent dye, and monosaccharide. Under the optimized conditions, the minimum concentration of monosaccharide that could be detected was 1 × 10−11 M. Finally, the developed device was used for the detection of 0.3 mM glucose spiked in human urine. All of the results demonstrated the feasibility of monosaccharide detection via the μFFE.
AbstractList	Here, a simple micro free‐flow electrophoresis (μFFE) was developed for fluorescence sensing of monosaccharide via supermolecule interaction of synthesized boronic acid functionalized benzyl viologen (ο‐BBV) and fluorescent dye. The μFFE contained two open electrode cavities and an ion‐exchange membrane was sandwiched between two polymethylmethacrylate plates. The experiments demonstrated the following merits of developed μFFE: (i) up to 90.5% of voltage efficiency due to high conductivity of ion‐exchange membrane; (ii) a strong ability against influence of bubble produced in two electrodes due to open design of electrode cavities; and (iii) reusable and washable separation chamber (45 mm × 17 mm × 100 μm, 77 μL) avoiding the discard of μFFE due to blockage of solute precipitation in chamber. Remarkably, the μFFE was first designed for the sensing of monosaccharide via the supermolecule interaction of synthesized ο‐BBV, fluorescent dye, and monosaccharide. Under the optimized conditions, the minimum concentration of monosaccharide that could be detected was 1 × 10−11 M. Finally, the developed device was used for the detection of 0.3 mM glucose spiked in human urine. All of the results demonstrated the feasibility of monosaccharide detection via the μFFE. Here, a simple micro free‐flow electrophoresis (μFFE) was developed for fluorescence sensing of monosaccharide via supermolecule interaction of synthesized boronic acid functionalized benzyl viologen ( ο ‐ BBV ) and fluorescent dye. The μ FFE contained two open electrode cavities and an ion‐exchange membrane was sandwiched between two polymethylmethacrylate plates. The experiments demonstrated the following merits of developed μ FFE : (i) up to 90.5% of voltage efficiency due to high conductivity of ion‐exchange membrane; (ii) a strong ability against influence of bubble produced in two electrodes due to open design of electrode cavities; and (iii) reusable and washable separation chamber (45 mm × 17 mm × 100 μm, 77 μL) avoiding the discard of μ FFE due to blockage of solute precipitation in chamber. Remarkably, the μ FFE was first designed for the sensing of monosaccharide via the supermolecule interaction of synthesized ο ‐ BBV , fluorescent dye, and monosaccharide. Under the optimized conditions, the minimum concentration of monosaccharide that could be detected was 1 × 10 −11 M. Finally, the developed device was used for the detection of 0.3 mM glucose spiked in human urine. All of the results demonstrated the feasibility of monosaccharide detection via the μ FFE . Here, a simple micro free-flow electrophoresis ( mu FFE) was developed for fluorescence sensing of monosaccharide via supermolecule interaction of synthesized boronic acid functionalized benzyl viologen ( omicron - BBV ) and fluorescent dye. The mu FFE contained two open electrode cavities and an ion-exchange membrane was sandwiched between two polymethylmethacrylate plates. The experiments demonstrated the following merits of developed mu FFE : (i) up to 90.5% of voltage efficiency due to high conductivity of ion-exchange membrane; (ii) a strong ability against influence of bubble produced in two electrodes due to open design of electrode cavities; and (iii) reusable and washable separation chamber (45 mm 17 mm 100 mu m, 77 mu L) avoiding the discard of mu FFE due to blockage of solute precipitation in chamber. Remarkably, the mu FFE was first designed for the sensing of monosaccharide via the supermolecule interaction of synthesized omicron - BBV , fluorescent dye, and monosaccharide. Under the optimized conditions, the minimum concentration of monosaccharide that could be detected was 1 10 super(-11) M. Finally, the developed device was used for the detection of 0.3 mM glucose spiked in human urine. All of the results demonstrated the feasibility of monosaccharide detection via the mu FFE . Here, a simple micro free-flow electrophoresis (μFFE) was developed for fluorescence sensing of monosaccharide via supermolecule interaction of synthesized boronic acid functionalized benzyl viologen (ο-BBV) and fluorescent dye. The μFFE contained two open electrode cavities and an ion-exchange membrane was sandwiched between two polymethylmethacrylate plates. The experiments demonstrated the following merits of developed μFFE: (i) up to 90.5% of voltage efficiency due to high conductivity of ion-exchange membrane; (ii) a strong ability against influence of bubble produced in two electrodes due to open design of electrode cavities; and (iii) reusable and washable separation chamber (45 mm × 17 mm × 100 μm, 77 μL) avoiding the discard of μFFE due to blockage of solute precipitation in chamber. Remarkably, the μFFE was first designed for the sensing of monosaccharide via the supermolecule interaction of synthesized ο-BBV, fluorescent dye, and monosaccharide. Under the optimized conditions, the minimum concentration of monosaccharide that could be detected was 1 × 10(-11) M. Finally, the developed device was used for the detection of 0.3 mM glucose spiked in human urine. All of the results demonstrated the feasibility of monosaccharide detection via the μFFE.Here, a simple micro free-flow electrophoresis (μFFE) was developed for fluorescence sensing of monosaccharide via supermolecule interaction of synthesized boronic acid functionalized benzyl viologen (ο-BBV) and fluorescent dye. The μFFE contained two open electrode cavities and an ion-exchange membrane was sandwiched between two polymethylmethacrylate plates. The experiments demonstrated the following merits of developed μFFE: (i) up to 90.5% of voltage efficiency due to high conductivity of ion-exchange membrane; (ii) a strong ability against influence of bubble produced in two electrodes due to open design of electrode cavities; and (iii) reusable and washable separation chamber (45 mm × 17 mm × 100 μm, 77 μL) avoiding the discard of μFFE due to blockage of solute precipitation in chamber. Remarkably, the μFFE was first designed for the sensing of monosaccharide via the supermolecule interaction of synthesized ο-BBV, fluorescent dye, and monosaccharide. Under the optimized conditions, the minimum concentration of monosaccharide that could be detected was 1 × 10(-11) M. Finally, the developed device was used for the detection of 0.3 mM glucose spiked in human urine. All of the results demonstrated the feasibility of monosaccharide detection via the μFFE. Here, a simple micro free-flow electrophoresis (μFFE) was developed for fluorescence sensing of monosaccharide via supermolecule interaction of synthesized boronic acid functionalized benzyl viologen (ο-BBV) and fluorescent dye. The μFFE contained two open electrode cavities and an ion-exchange membrane was sandwiched between two polymethylmethacrylate plates. The experiments demonstrated the following merits of developed μFFE: (i) up to 90.5% of voltage efficiency due to high conductivity of ion-exchange membrane; (ii) a strong ability against influence of bubble produced in two electrodes due to open design of electrode cavities; and (iii) reusable and washable separation chamber (45 mm × 17 mm × 100 μm, 77 μL) avoiding the discard of μFFE due to blockage of solute precipitation in chamber. Remarkably, the μFFE was first designed for the sensing of monosaccharide via the supermolecule interaction of synthesized ο-BBV, fluorescent dye, and monosaccharide. Under the optimized conditions, the minimum concentration of monosaccharide that could be detected was 1 × 10(-11) M. Finally, the developed device was used for the detection of 0.3 mM glucose spiked in human urine. All of the results demonstrated the feasibility of monosaccharide detection via the μFFE.
Author	Wang, Hou-Yu Yin, Xiao-Yang Li, Si Cao, Cheng-Xi Fan, Liu-Yin Dong, Jing-Yu
Author_xml	– sequence: 1 givenname: Xiao-Yang surname: Yin fullname: Yin, Xiao-Yang organization: Laboratory of Bio-Separation and Analytical Biochemistry, State Key Laboratory of Microbial Metabolism and School of Life Science and Biotechnology, Shanghai Jiao Tong University, Shanghai, P. R. China – sequence: 2 givenname: Jing-Yu surname: Dong fullname: Dong, Jing-Yu organization: Laboratory of Bio-Separation and Analytical Biochemistry, State Key Laboratory of Microbial Metabolism and School of Life Science and Biotechnology, Shanghai Jiao Tong University, Shanghai, P. R. China – sequence: 3 givenname: Hou-Yu surname: Wang fullname: Wang, Hou-Yu organization: Laboratory of Bio-Separation and Analytical Biochemistry, State Key Laboratory of Microbial Metabolism and School of Life Science and Biotechnology, Shanghai Jiao Tong University, Shanghai, P. R. China – sequence: 4 givenname: Si surname: Li fullname: Li, Si organization: Laboratory of Bio-Separation and Analytical Biochemistry, State Key Laboratory of Microbial Metabolism and School of Life Science and Biotechnology, Shanghai Jiao Tong University, Shanghai, P. R. China – sequence: 5 givenname: Liu-Yin surname: Fan fullname: Fan, Liu-Yin email: lyfan@sjtu.edu.cncxcao@sjtu.edu.cn organization: Laboratory of Bio-Separation and Analytical Biochemistry, State Key Laboratory of Microbial Metabolism and School of Life Science and Biotechnology, Shanghai Jiao Tong University, Shanghai, P. R. China – sequence: 6 givenname: Cheng-Xi surname: Cao fullname: Cao, Cheng-Xi email: lyfan@sjtu.edu.cncxcao@sjtu.edu.cn organization: Laboratory of Bio-Separation and Analytical Biochemistry, State Key Laboratory of Microbial Metabolism and School of Life Science and Biotechnology, Shanghai Jiao Tong University, Shanghai, P. R. China
BackLink	https://www.ncbi.nlm.nih.gov/pubmed/23712879$$D View this record in MEDLINE/PubMed
BookMark	eNqNkT1vFDEQhi0URC6BlhK5pNnDn_tRRlEISBeIRAil5fWOOYPXXuxdwvFb-LHscuEKmlBNMc8zM5r3BB2FGACh55SsKSHsFfghrxmhnBBKxCO0opKxgpU1P0IrQitekJrLY3SS8xdCiGiEeIKOGa8oq6tmhX6d4ez6wQM2WzdgmwAK6-MdBg9mTHHYxgTZZWxjwn0MMWtjtjq5DnCGkF34jL87jfM0QOrjLE3zLBdGSNqMLgYcLW5jisEZrI3rsJ3Cn4b27id0-NsEwWwhYR3mnp-WdQbCiLsdPEWPrfYZnt3XU_Tx9cXN-Zti8_7y7fnZpjCCUlF0GmTZMSK6kgOxjZQWOKPWmsq02hojiCyrWtfNTDZEtrKGUjStZG1XCuD8FL3czx1SnO_Jo-rdfIT3OkCcsqKCN1UliaT_gdKaiprWYkZf3KNT20OnhuR6nXbq7_NnYL0HTIo5J7AHhBK1pKuWdNUh3VkQ_wjGjXp55pi08w9qd87D7oEl6mJz_UFUYtGKvebyCD8Omk5fVVnxSqpP7y7V7c3tVUmurhXnvwGROsxH
CitedBy_id	crossref_primary_10_1021_cr500562m crossref_primary_10_1007_s00604_014_1398_z crossref_primary_10_1021_ac501081b crossref_primary_10_1021_acs_analchem_6b02235 crossref_primary_10_1186_s13065_014_0060_5 crossref_primary_10_1002_elps_201500258 crossref_primary_10_1007_s00216_017_0697_8 crossref_primary_10_1002_ejoc_202000396
Cites_doi	10.1002/elps.201100358 10.1002/jssc.201100293 10.1002/elps.1150100302 10.1016/j.chroma.2008.12.024 10.1074/mcp.T600018-MCP200 10.1002/elps.1150190712 10.1002/elps.200800609 10.1016/S0021-9673(97)01114-X 10.1093/clinchem/45.9.1596 10.1039/b514731j 10.1002/elps.201200169 10.1002/elps.1150110603 10.1002/elps.1150111111 10.1002/elps.200700725 10.1021/ac00030a001 10.1021/ja066567i 10.1016/j.chroma.2010.01.085 10.1002/elps.1150191021 10.1002/ange.200701888 10.1021/ac0345190 10.1021/ac050766n 10.1021/ac9025219 10.1002/elps.1150190704 10.1021/ac00090a011 10.1021/ac00074a001 10.1021/pr0600632 10.1002/jssc.201000162 10.1002/elps.200600137 10.1016/0022-2313(75)90003-4 10.1016/0378-4347(94)00042-5 10.1039/b308476k 10.1016/S0076-6879(89)71028-4
ContentType	Journal Article
Copyright	2013 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Copyright_xml	– notice: 2013 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim – notice: 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
DBID	BSCLL AAYXX CITATION CGR CUY CVF ECM EIF NPM 7X8 7U5 8FD L7M
DOI	10.1002/elps.201300104
DatabaseName	Istex CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed MEDLINE - Academic Solid State and Superconductivity Abstracts Technology Research Database Advanced Technologies Database with Aerospace
DatabaseTitle	CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) MEDLINE - Academic Technology Research Database Advanced Technologies Database with Aerospace Solid State and Superconductivity Abstracts
DatabaseTitleList	CrossRef Technology Research Database MEDLINE - Academic MEDLINE
Database_xml	– sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database
DeliveryMethod	fulltext_linktorsrc
Discipline	Chemistry
EISSN	1522-2683
EndPage	2192
ExternalDocumentID	23712879 10_1002_elps_201300104 ELPS4744 ark_67375_WNG_VTVM60MP_3
Genre	article Research Support, Non-U.S. Gov't Journal Article
GrantInformation_xml	– fundername: National Key Program of Scientific Instrument of China funderid: 2011YQ030139 – fundername: NSFC funderid: 21035004; 21275099
GroupedDBID	--- .3N .GA .GJ .Y3 05W 0R~ 10A 1L6 1OB 1OC 1ZS 31~ 33P 3SF 3WU 4.4 4ZD 50Y 50Z 51W 51X 52M 52N 52O 52P 52S 52T 52U 52W 52X 53G 5GY 5RE 5VS 66C 702 7PT 8-0 8-1 8-3 8-4 8-5 8UM 930 A03 AAESR AAEVG AAHBH AAHHS AANLZ AAONW AASGY AAXRX AAZKR ABCQN ABCUV ABEML ABIJN ABJNI ABPVW ACAHQ ACBWZ ACCFJ ACCZN ACFBH ACGFS ACPOU ACSCC ACXBN ACXQS ADBBV ADEOM ADIZJ ADKYN ADMGS ADOZA ADXAS ADZMN ADZOD AEEZP AEIGN AEIMD AENEX AEQDE AEUQT AEUYR AFBPY AFFNX AFFPM AFGKR AFPWT AFZJQ AHBTC AI. AITYG AIURR AIWBW AJBDE AJXKR ALAGY ALMA_UNASSIGNED_HOLDINGS ALUQN AMBMR AMYDB AQPKS ASPBG ATUGU AUFTA AVWKF AZBYB AZFZN AZVAB BAFTC BDRZF BFHJK BHBCM BMNLL BMXJE BNHUX BROTX BRXPI BSCLL BY8 CS3 D-E D-F DCZOG DPXWK DR1 DR2 DRFUL DRSTM DU5 EBD EBS EJD EMOBN F00 F01 F04 F5P FEDTE G-S G.N GNP GODZA H.T H.X HBH HF~ HGLYW HHY HHZ HVGLF HZ~ IX1 J0M JPC KQQ LATKE LAW LC2 LC3 LEEKS LH4 LH5 LITHE LOXES LP6 LP7 LUTES LW6 LYRES MEWTI MK4 MRFUL MRSTM MSFUL MSSTM MXFUL MXSTM N04 N05 N9A NF~ NNB O66 O9- OIG P2P P2W P2X P4D PALCI Q.N Q11 QB0 QRW R.K RIWAO RJQFR RNS ROL RWI RX1 RYL SAMSI SUPJJ SV3 UB1 V2E VH1 W8V W99 WBKPD WIB WIH WIK WJL WNSPC WOHZO WQJ WRC WRJ WXSBR WYISQ XG1 XPP XV2 Y6R ZGI ZXP ZZTAW ~IA ~KM ~WT AAHQN AAMNL AANHP AAYCA ACRPL ACYXJ ADNMO AFWVQ ALVPJ AAYXX AEYWJ AGHNM AGQPQ AGYGG CITATION AAMMB AEFGJ AGXDD AIDQK AIDYY CGR CUY CVF ECM EIF NPM 7X8 7U5 8FD L7M
ID	FETCH-LOGICAL-c4114-dae56d204d63e0f955fe321ffc7cbafcc405678a89dae905b58e649b52bd64e33
IEDL.DBID	DR2
ISSN	0173-0835 1522-2683
IngestDate	Fri Jul 11 03:38:19 EDT 2025 Fri Jul 11 01:41:33 EDT 2025 Mon Jul 21 06:01:50 EDT 2025 Thu Apr 24 22:55:20 EDT 2025 Tue Jul 01 04:02:58 EDT 2025 Wed Jan 22 16:50:00 EST 2025 Wed Oct 30 09:48:29 EDT 2024
IsPeerReviewed	true
IsScholarly	true
Issue	15
Keywords	Micro free-flow electrophoresis Supermolecule interaction Monosaccharide
Language	English
License	http://onlinelibrary.wiley.com/termsAndConditions#vor 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
LinkModel	DirectLink
MergedId	FETCHMERGED-LOGICAL-c4114-dae56d204d63e0f955fe321ffc7cbafcc405678a89dae905b58e649b52bd64e33
Notes	ark:/67375/WNG-VTVM60MP-3 istex:5EE6BA0B3DE89D51480A95ED1F35C1E8B1ED458D NSFC - No. 21035004; No. 21275099 National Key Program of Scientific Instrument of China - No. 2011YQ030139 ArticleID:ELPS4744 See the article online to view Figs. 1–5 in colour. These authors have contributed equally to the paper. Colour Online ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 ObjectType-Article-2 ObjectType-Feature-1
PMID	23712879
PQID	1418148184
PQPubID	23479
PageCount	8
ParticipantIDs	proquest_miscellaneous_1439775051 proquest_miscellaneous_1418148184 pubmed_primary_23712879 crossref_primary_10_1002_elps_201300104 crossref_citationtrail_10_1002_elps_201300104 wiley_primary_10_1002_elps_201300104_ELPS4744 istex_primary_ark_67375_WNG_VTVM60MP_3
ProviderPackageCode	CITATION AAYXX
PublicationCentury	2000
PublicationDate	August 2013
PublicationDateYYYYMMDD	2013-08-01
PublicationDate_xml	– month: 08 year: 2013 text: August 2013
PublicationDecade	2010
PublicationPlace	Germany
PublicationPlace_xml	– name: Germany
PublicationTitle	Electrophoresis
PublicationTitleAlternate	ELECTROPHORESIS
PublicationYear	2013
Publisher	Blackwell Publishing Ltd
Publisher_xml	– name: Blackwell Publishing Ltd
References	Xu, Y., Zhang, C. X., Janasek, D., Manz, A., Lab Chip 2003, 3, 224-227. Shao, J., Li, S., Zhang, W., Fan, L. Y., Cao, C. X., Sun, R., Dong, Y. C., J. Chromatogr. A 2010, 1217, 2182-2186. Kuhn, R., Wagner, H., Electrophoresis 1989, 10, 165-172. Schiller, A., Wessling, R. A., Singaram, B., Angew. Chem. 2007, 119, 6577-6579. Zhang, C. X., Manz, A., Anal. Chem. 2003, 75, 5759-5766. Dong, Y. C., Shao, J., Yin, X. Y., Fan, L. Y., Cao, C. X., J. Sep. Sci. 2011, 34, 1683-1691. Horká, M., Horký, J., Matoušková, H., Šlais, K., J. Chromatogr. A 2009, 1216, 1019-1024. Reach, G., Wilson, G. S., Anal. Chem. 1992, 64, 381A-386A. Kohlheyer, D., Besselink, G. A. J., Schlautmann, S., Schasfoort, R. B. M., Lab Chip 2006, 6, 374-380. Weber, G., Bocek, P., Electrophoresis 1998, 19, 1649-1653. Loseva, O. I., Gavryushkin, A. V., Osipov, V. V., Vanyakin, E. N., Electrophoresis 1998, 19, 1127-1134. Shao, J., Fan, L. Y., Cao, C. X., Huang, X. Q., Xu, Y. Q., Electrophoresis 2012, 33, 2065-2074. Kohlheyer, D., Eijkel, J. C. T., van den Berg, A., Schasfoort, R. B. M., Electrophoresis 2008, 29, 977-993. Song, Y. A., Chan, M., Celio, C., Tannenbaum, S. R., Wishnok, J. S., Han, J., Anal. Chem. 2010, 82, 2317-2325. Kuhn, R., Hoffstetter-Kuhn, S., Wagner, H., Electrophoresis 1990, 11, 942-947. Wang, P. L., Zhang, L. H., Shan, Y. C., Cong, Y. Z., Liang, Y., Han, B., Liang, Z., Zhang, Y. K., J. Sep. Sci. 2010, 33, 2039-2044. Heidrich, H. G., Hannig, K., Meth. Enzymol. 1989, 171, 513-531. Roman, M. C., Brown, P. R., Anal. Chem. 1994, 66, 86A-94A. Stein, G., Flad, H. D., Pabst, R., Trepel, F., Biomedicine 1973, 19, 388-391. Zischka, H., Braun, R. J., Marantidis, E. P., Buringer, D., Bornhovd, C., Hauck, S. M., Demmer, O., Gloeckner, C. J., Reichert, A. S., Madeo, F., Ueffing, M., Mol. Cell. Proteomics 2006, 5, 2185-2200. Fonslow, B. R., Bowser, M. T., Anal. Chem. 2005, 77, 5706-5710. de Jesus, D. P., Blanes, L., do Lago, C. L., Electrophoresis 2006, 27, 4935-4942. Krivankova, L., Bocek, P., Electrophoresis 1998, 19, 1064-1074. Geng, J. Z., Shao, J., Yang, J. H., Pang, B., Cao, C. X., Fan, L. Y., Electrophoresis 2011, 32, 3248-3256. Hoffstetter-Kuhn, S., Wagner, H., Electrophoresis 1990, 11, 451-456. Kasicka, V., Prusik, Z., Sazelova, P., Jiracek, J., Barth, T., J. Chromatogr. A 1998, 796, 211-220. Martin, M. M., Lindqvist, L., J. Lumin. 1975, 10, 381-390. Turner, A. P., Chen, B., Piletsky, S. A., Clin. Chem. 1999, 45, 1596-1601. Gamsey, S., Miller, A., Olmstead, M. M., Beavers, C. M., Hirayama, L. C., Pradhan, S., Wessling, R. A., Singaram, B., J. Am. Chem. Soc. 2007, 129, 1278-1286. Kasicka, V., Prusik, Z., Smekal, O., Hlavacek, J., Barth, T., Weber, G., Wagner, H., J. Chromatogr. B Biomed. Appl. 1994, 656, 99-106. Chen, S., Palmer, J. F., Zhang, W., Shao, J., Li, S., Fan, L. Y., Sun, R., Dong, Y. C., Cao, C. X., Electrophoresis 2009, 30, 1998-2007. Malmstrom, J., Lee, H., Nesvizhskii, A. I., Shteynberg, D., Mohanty, S., Brunner, E., Ye, M. L., Weber, G., Eckerskorn, C., Aebersold, R., J. Proteome. Res. 2006, 5, 2241-2249. Raymond, D. E., Manz, A., Widmer, H. M., Anal. Chem. 1994, 66, 2858-2865. 2010; 33 1990; 11 2007; 129 1994; 656 1973; 19 2010; 1217 1994; 66 1999; 45 2006; 5 2011; 32 2006; 6 2011; 34 1998; 796 1975; 10 2012; 33 2003; 75 2010; 82 2009; 1216 2009; 30 1998; 19 2007; 119 1989; 10 2008; 29 2006; 27 1989; 171 2003; 3 1992; 64 2005; 77 e_1_2_7_6_1 e_1_2_7_5_1 e_1_2_7_4_1 e_1_2_7_9_1 e_1_2_7_8_1 e_1_2_7_7_1 e_1_2_7_19_1 e_1_2_7_18_1 e_1_2_7_17_1 e_1_2_7_16_1 e_1_2_7_2_1 e_1_2_7_15_1 e_1_2_7_14_1 e_1_2_7_13_1 e_1_2_7_12_1 e_1_2_7_11_1 e_1_2_7_10_1 e_1_2_7_26_1 e_1_2_7_27_1 e_1_2_7_28_1 e_1_2_7_29_1 Stein G. (e_1_2_7_3_1) 1973; 19 e_1_2_7_30_1 e_1_2_7_25_1 e_1_2_7_31_1 e_1_2_7_24_1 e_1_2_7_32_1 e_1_2_7_23_1 e_1_2_7_33_1 e_1_2_7_22_1 e_1_2_7_34_1 e_1_2_7_21_1 e_1_2_7_20_1
References_xml	– reference: Kuhn, R., Hoffstetter-Kuhn, S., Wagner, H., Electrophoresis 1990, 11, 942-947. – reference: Chen, S., Palmer, J. F., Zhang, W., Shao, J., Li, S., Fan, L. Y., Sun, R., Dong, Y. C., Cao, C. X., Electrophoresis 2009, 30, 1998-2007. – reference: Malmstrom, J., Lee, H., Nesvizhskii, A. I., Shteynberg, D., Mohanty, S., Brunner, E., Ye, M. L., Weber, G., Eckerskorn, C., Aebersold, R., J. Proteome. Res. 2006, 5, 2241-2249. – reference: Xu, Y., Zhang, C. X., Janasek, D., Manz, A., Lab Chip 2003, 3, 224-227. – reference: Horká, M., Horký, J., Matoušková, H., Šlais, K., J. Chromatogr. A 2009, 1216, 1019-1024. – reference: Roman, M. C., Brown, P. R., Anal. Chem. 1994, 66, 86A-94A. – reference: Shao, J., Li, S., Zhang, W., Fan, L. Y., Cao, C. X., Sun, R., Dong, Y. C., J. Chromatogr. A 2010, 1217, 2182-2186. – reference: Martin, M. M., Lindqvist, L., J. Lumin. 1975, 10, 381-390. – reference: Kuhn, R., Wagner, H., Electrophoresis 1989, 10, 165-172. – reference: Schiller, A., Wessling, R. A., Singaram, B., Angew. Chem. 2007, 119, 6577-6579. – reference: Gamsey, S., Miller, A., Olmstead, M. M., Beavers, C. M., Hirayama, L. C., Pradhan, S., Wessling, R. A., Singaram, B., J. Am. Chem. Soc. 2007, 129, 1278-1286. – reference: Hoffstetter-Kuhn, S., Wagner, H., Electrophoresis 1990, 11, 451-456. – reference: Turner, A. P., Chen, B., Piletsky, S. A., Clin. Chem. 1999, 45, 1596-1601. – reference: Stein, G., Flad, H. D., Pabst, R., Trepel, F., Biomedicine 1973, 19, 388-391. – reference: Kohlheyer, D., Besselink, G. A. J., Schlautmann, S., Schasfoort, R. B. M., Lab Chip 2006, 6, 374-380. – reference: Song, Y. A., Chan, M., Celio, C., Tannenbaum, S. R., Wishnok, J. S., Han, J., Anal. Chem. 2010, 82, 2317-2325. – reference: Fonslow, B. R., Bowser, M. T., Anal. Chem. 2005, 77, 5706-5710. – reference: Heidrich, H. G., Hannig, K., Meth. Enzymol. 1989, 171, 513-531. – reference: Geng, J. Z., Shao, J., Yang, J. H., Pang, B., Cao, C. X., Fan, L. Y., Electrophoresis 2011, 32, 3248-3256. – reference: Zischka, H., Braun, R. J., Marantidis, E. P., Buringer, D., Bornhovd, C., Hauck, S. M., Demmer, O., Gloeckner, C. J., Reichert, A. S., Madeo, F., Ueffing, M., Mol. Cell. Proteomics 2006, 5, 2185-2200. – reference: Loseva, O. I., Gavryushkin, A. V., Osipov, V. V., Vanyakin, E. N., Electrophoresis 1998, 19, 1127-1134. – reference: Raymond, D. E., Manz, A., Widmer, H. M., Anal. Chem. 1994, 66, 2858-2865. – reference: de Jesus, D. P., Blanes, L., do Lago, C. L., Electrophoresis 2006, 27, 4935-4942. – reference: Kohlheyer, D., Eijkel, J. C. T., van den Berg, A., Schasfoort, R. B. M., Electrophoresis 2008, 29, 977-993. – reference: Zhang, C. X., Manz, A., Anal. Chem. 2003, 75, 5759-5766. – reference: Weber, G., Bocek, P., Electrophoresis 1998, 19, 1649-1653. – reference: Kasicka, V., Prusik, Z., Smekal, O., Hlavacek, J., Barth, T., Weber, G., Wagner, H., J. Chromatogr. B Biomed. Appl. 1994, 656, 99-106. – reference: Shao, J., Fan, L. Y., Cao, C. X., Huang, X. Q., Xu, Y. Q., Electrophoresis 2012, 33, 2065-2074. – reference: Krivankova, L., Bocek, P., Electrophoresis 1998, 19, 1064-1074. – reference: Dong, Y. C., Shao, J., Yin, X. Y., Fan, L. Y., Cao, C. X., J. Sep. Sci. 2011, 34, 1683-1691. – reference: Reach, G., Wilson, G. S., Anal. Chem. 1992, 64, 381A-386A. – reference: Kasicka, V., Prusik, Z., Sazelova, P., Jiracek, J., Barth, T., J. Chromatogr. A 1998, 796, 211-220. – reference: Wang, P. L., Zhang, L. H., Shan, Y. C., Cong, Y. Z., Liang, Y., Han, B., Liang, Z., Zhang, Y. K., J. Sep. Sci. 2010, 33, 2039-2044. – volume: 29 start-page: 977 year: 2008 end-page: 993 publication-title: Electrophoresis – volume: 6 start-page: 374 year: 2006 end-page: 380 publication-title: Lab Chip – volume: 10 start-page: 381 year: 1975 end-page: 390 publication-title: J. Lumin. – volume: 5 start-page: 2185 year: 2006 end-page: 2200 publication-title: Mol. Cell. Proteomics – volume: 119 start-page: 6577 year: 2007 end-page: 6579 publication-title: Angew. Chem. – volume: 3 start-page: 224 year: 2003 end-page: 227 publication-title: Lab Chip – volume: 5 start-page: 2241 year: 2006 end-page: 2249 publication-title: J. Proteome. Res. – volume: 82 start-page: 2317 year: 2010 end-page: 2325 publication-title: Anal. Chem. – volume: 33 start-page: 2065 year: 2012 end-page: 2074 publication-title: Electrophoresis – volume: 19 start-page: 1127 year: 1998 end-page: 1134 publication-title: Electrophoresis – volume: 33 start-page: 2039 year: 2010 end-page: 2044 publication-title: J. Sep. Sci. – volume: 75 start-page: 5759 year: 2003 end-page: 5766 publication-title: Anal. Chem. – volume: 34 start-page: 1683 year: 2011 end-page: 1691 publication-title: J. Sep. Sci. – volume: 77 start-page: 5706 year: 2005 end-page: 5710 publication-title: Anal. Chem. – volume: 19 start-page: 388 year: 1973 end-page: 391 publication-title: Biomedicine – volume: 11 start-page: 942 year: 1990 end-page: 947 publication-title: Electrophoresis – volume: 64 start-page: 381A year: 1992 end-page: 386A publication-title: Anal. Chem. – volume: 27 start-page: 4935 year: 2006 end-page: 4942 publication-title: Electrophoresis – volume: 129 start-page: 1278 year: 2007 end-page: 1286 publication-title: J. Am. Chem. Soc. – volume: 796 start-page: 211 year: 1998 end-page: 220 publication-title: J. Chromatogr. A – volume: 19 start-page: 1064 year: 1998 end-page: 1074 publication-title: Electrophoresis – volume: 1217 start-page: 2182 year: 2010 end-page: 2186 publication-title: J. Chromatogr. A – volume: 45 start-page: 1596 year: 1999 end-page: 1601 publication-title: Clin. Chem. – volume: 66 start-page: 2858 year: 1994 end-page: 2865 publication-title: Anal. Chem. – volume: 1216 start-page: 1019 year: 2009 end-page: 1024 publication-title: J. Chromatogr. A – volume: 656 start-page: 99 year: 1994 end-page: 106 publication-title: J. Chromatogr. B Biomed. Appl. – volume: 19 start-page: 1649 year: 1998 end-page: 1653 publication-title: Electrophoresis – volume: 171 start-page: 513 year: 1989 end-page: 531 publication-title: Meth. Enzymol. – volume: 32 start-page: 3248 year: 2011 end-page: 3256 publication-title: Electrophoresis – volume: 66 start-page: 86A year: 1994 end-page: 94A publication-title: Anal. Chem. – volume: 30 start-page: 1998 year: 2009 end-page: 2007 publication-title: Electrophoresis – volume: 10 start-page: 165 year: 1989 end-page: 172 publication-title: Electrophoresis – volume: 11 start-page: 451 year: 1990 end-page: 456 publication-title: Electrophoresis – ident: e_1_2_7_7_1 doi: 10.1002/elps.201100358 – ident: e_1_2_7_4_1 doi: 10.1002/jssc.201100293 – ident: e_1_2_7_8_1 doi: 10.1002/elps.1150100302 – ident: e_1_2_7_5_1 doi: 10.1016/j.chroma.2008.12.024 – ident: e_1_2_7_6_1 doi: 10.1074/mcp.T600018-MCP200 – ident: e_1_2_7_11_1 doi: 10.1002/elps.1150190712 – ident: e_1_2_7_26_1 doi: 10.1002/elps.200800609 – ident: e_1_2_7_15_1 doi: 10.1016/S0021-9673(97)01114-X – ident: e_1_2_7_28_1 doi: 10.1093/clinchem/45.9.1596 – ident: e_1_2_7_34_1 doi: 10.1039/b514731j – ident: e_1_2_7_27_1 doi: 10.1002/elps.201200169 – ident: e_1_2_7_9_1 doi: 10.1002/elps.1150110603 – ident: e_1_2_7_14_1 doi: 10.1002/elps.1150111111 – ident: e_1_2_7_20_1 doi: 10.1002/elps.200700725 – ident: e_1_2_7_29_1 doi: 10.1021/ac00030a001 – ident: e_1_2_7_31_1 doi: 10.1021/ja066567i – ident: e_1_2_7_32_1 doi: 10.1016/j.chroma.2010.01.085 – ident: e_1_2_7_19_1 doi: 10.1002/elps.1150191021 – ident: e_1_2_7_30_1 doi: 10.1002/ange.200701888 – ident: e_1_2_7_22_1 doi: 10.1021/ac0345190 – ident: e_1_2_7_24_1 doi: 10.1021/ac050766n – ident: e_1_2_7_10_1 doi: 10.1021/ac9025219 – ident: e_1_2_7_18_1 doi: 10.1002/elps.1150190704 – volume: 19 start-page: 388 year: 1973 ident: e_1_2_7_3_1 publication-title: Biomedicine – ident: e_1_2_7_21_1 doi: 10.1021/ac00090a011 – ident: e_1_2_7_17_1 doi: 10.1021/ac00074a001 – ident: e_1_2_7_12_1 doi: 10.1021/pr0600632 – ident: e_1_2_7_16_1 doi: 10.1002/jssc.201000162 – ident: e_1_2_7_25_1 doi: 10.1002/elps.200600137 – ident: e_1_2_7_33_1 doi: 10.1016/0022-2313(75)90003-4 – ident: e_1_2_7_13_1 doi: 10.1016/0378-4347(94)00042-5 – ident: e_1_2_7_23_1 doi: 10.1039/b308476k – ident: e_1_2_7_2_1 doi: 10.1016/S0076-6879(89)71028-4
SSID	ssj0004944
Score	2.1243994
Snippet	Here, a simple micro free‐flow electrophoresis (μFFE) was developed for fluorescence sensing of monosaccharide via supermolecule interaction of synthesized... Here, a simple micro free-flow electrophoresis (μFFE) was developed for fluorescence sensing of monosaccharide via supermolecule interaction of synthesized... Here, a simple micro free-flow electrophoresis ( mu FFE) was developed for fluorescence sensing of monosaccharide via supermolecule interaction of synthesized...
SourceID	proquest pubmed crossref wiley istex
SourceType	Aggregation Database Index Database Enrichment Source Publisher
StartPage	2185
SubjectTerms	Benzyl Viologen - chemistry Boronic Acids - chemistry Chambers Detection Dyes Electrodes Electrophoresis Electrophoresis - instrumentation Electrophoresis - methods Fluorescent Dyes - chemistry Glycosuria - urine Humans Membranes Micro free-flow electrophoresis Microtechnology - instrumentation Monosaccharide Monosaccharides Monosaccharides - analysis Monosaccharides - chemistry Monosaccharides - urine Reusable Spectrometry, Fluorescence - methods Supermolecule interaction
Title	A simple chip free-flow electrophoresis for monosaccharide sensing via supermolecule interaction of boronic acid functionalized quencher and fluorescent dye
URI	https://api.istex.fr/ark:/67375/WNG-VTVM60MP-3/fulltext.pdf https://onlinelibrary.wiley.com/doi/abs/10.1002%2Felps.201300104 https://www.ncbi.nlm.nih.gov/pubmed/23712879 https://www.proquest.com/docview/1418148184 https://www.proquest.com/docview/1439775051
Volume	34
hasFullText	1
inHoldings	1
isFullTextHit
isPrint
link	http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV3JbtRAEG2hcIAL-zJsaiQEJye2u9seH6MoIUJMFEEScrN6qU6sjGxrPGbJiU_gC_g4voQqezxhEIsQZ5fV22vXa3fVK8aeeSlCQKYReGt9gKAIg3Hm40BIp2IvqPo2ZSNP9pLdQ_nqWB3_kMXf60Msf7jRzui-17TBtWk2LkRDYVqT3DZdx0SdICgFbBErenOhHyUz2Yt7p4JkmNWg2hjGG6uvr3ilyzTBH39FOVcZbOeCdq4zPXS-jzw5W2_nZt2e_6Tr-D-ju8GuLfgp3-wBdZNdgvIWu7I1lIW7zb5u8qYgSWFuT4ua-xnAt89f_LT6wBclderTCs_wRcORD3NEedVoS8ldhQPeULx8ecLfF5o3bY1uoS_PC5x0K2Z9lgWvPDdVJ9rLtS0cJ-fb_7MszsHxLvgbscZ1ic-mLTVHQabcfYI77HBn-2BrN1gUeQisxLNY4DSoxMWhdImA0GdKeRBx5L1NrdGIIGSU6FD1OEPLLFRGjSGRmVGxcYkEIe6ytbIq4T7jBjJttYsSQzKLIjQQxpACFbLIIuXtiAXDIud2oYBOhTimea_dHOc06_ly1kfsxdK-7rU_fmv5vMPM0kzPzihiLlX5u72X-dHB0SQJJ_u5GLGnA6hyXDe6nNElVG2DRzDkWhLpk_yTDdF15KzRiN3rEblsMRYpUo00w0F2uPpLj_Pt1_tvZSrlg3-0f8iuxl1FEIqBfMTW5rMWHiMvm5sn3d77DhApNRk
linkProvider	Wiley-Blackwell
linkToHtml	http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV3LbtQwFLVQuygb3tDhaSQEq7SZ2E4my6pqGWBmVMG0sIts55pGHSWjyYRHV3wCX8DH8SXcm0xSDeIhxDo38es499i-PpexJ04KH5BpeM5a5yEofG8Qu8ATMlWBE5R9m24jjyfh8Fi-fKfaaEK6C9PoQ3QbbjQz6v81TXDakN69UA2F2Zz0tuk8pk-KoJv04XpV9fpCQUrGspH3jgQJMatWt9EPdtffX_NLm9TFn35FOtc5bO2EDq8y01a_iT0526mWZsee_6Ts-F_tu8aurCgq32swdZ1dgvwG29pvM8PdZN_2eJmRqjC3p9mcuwXA9y9f3az4yFdZdeanBS7js5IjJeYI9KLUlu53ZSnwkkLm8_f8Q6Z5Wc3RMzQZeoGTdMWiuWjBC8dNUev2cm2zlJP_bbYts3NIeR3_jXDjOsdns4qKozhTnn6GW-z48GC6P_RWeR48K3E55qUaVJgGvkxDAb6LlXIggr5zNrJGI4iQVKJP1YMYLWNfGTWAUMZGBSYNJQhxm23kRQ7bjBuItdVpPzSktCh8A34AEVAui7ivnO0xrx3lxK5E0CkXxyxp5JuDhHo96Xq9x5519vNG_uO3lk9r0HRmenFGQXORSt5Onicn05Nx6I-PEtFjj1tUJThudD6jcyiqEldhSLckMij5Jxti7Ehb-z12p4FkV2IgImQbUYyNrIH1lxonB6OjNzKS8u4_2j9iW8PpeJSMXkxe3WOXgzpBCIVE3mcby0UFD5CmLc3DeiL-ADT8OTQ
linkToPdf	http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwpV3bbtNAEF2hVgJeuFPCdZEQPLm1vbt2_Fi1DQWaKIK29M1a785Sq5FtxQmXPvEJfEE_rl_CjJ2kBHER4tlj7e2s56x35gxjz5wUPiDT8JwxzkNQ-F43caEnpFWhE1R9m7KR-4No90C-PlJHP2Txt_oQix9utDOa7zVt8Mq6jQvRUBhVJLdN1zEBCYKuysjvEq63314ISMlEturesSAdZjWXbfTDjeX3l9zSKs3w519xzmUK2_ig3nWm571vQ09O1qeTbN2c_iTs-D_Du8GuzQgq32wRdZNdguIWu7I1rwt3m51t8jonTWFujvOKuzHA-ddvblR-4rOaOtVxiYf4vOZIiDnCvKy1oeyu3AKvKWC--MA_5prX0wr9QlufFzgJV4zbNAteOp6VjWov1ya3nLxv-9MyPwXLm-hvBBvXBT4bTak5ijLl9gvcYQe9nf2tXW9W5cEzEg9jntWgIhv60kYCfJco5UCEgXMmNplGCCGlRI-quwlaJr7KVBcimWQqzGwkQYi7bKUoC7jHeAaJNtoGUUY6i8LPwA8hBqpkkQTKmQ7z5oucmpkEOlXiGKWteHOY0qyni1nvsBcL-6oV__it5fMGMwszPT6hkLlYpe8HL9PD_cN-5PeHqeiwp3NQpbhudDujCyinNZ7BkGxJ5E_yTzbE15G0Bh221iJy0WIoYuQacYKDbHD1lx6nO3vDdzKW8v4_2j9hl4fbvXTv1eDNA3Y1bKqDUDzkQ7YyGU_hEXK0Sfa42YbfAYaeN-w
openUrl	ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=A+simple+chip+free%E2%80%90flow+electrophoresis+for+monosaccharide+sensing+via+supermolecule+interaction+of+boronic+acid+functionalized+quencher+and+fluorescent+dye&rft.jtitle=Electrophoresis&rft.au=Yin%2C+Xiao%E2%80%90Yang&rft.au=Dong%2C+Jing%E2%80%90Yu&rft.au=Wang%2C+Hou%E2%80%90Yu&rft.au=Li%2C+Si&rft.date=2013-08-01&rft.issn=0173-0835&rft.eissn=1522-2683&rft.volume=34&rft.issue=15&rft.spage=2185&rft.epage=2192&rft_id=info:doi/10.1002%2Felps.201300104&rft.externalDBID=10.1002%252Felps.201300104&rft.externalDocID=ELPS4744
thumbnail_l	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0173-0835&client=summon
thumbnail_m	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0173-0835&client=summon
thumbnail_s	http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0173-0835&client=summon