Tau accumulates in Crohn's disease gut

• Published in: The FASEB journal Vol. 34; no. 7; p. 9285
• Main Authors: Prigent, Alice, Chapelet, Guillaume, De Guilhem de Lataillade, Adrien, Oullier, Thibauld, Durieu, Emilie, Bourreille, Arnaud, Duchalais, Emilie, Hardonnière, Kévin, Neunlist, Michel, Noble, Wendy, Kerdine-Römer, Saadia, Derkinderen, Pascal, Rolli-Derkinderen, Malvyne
• Format: Journal Article
• Language: English
• Published: United States 01.07.2020
• Subjects: Animals; Case-Control Studies; Colitis, Ulcerative - metabolism; Colitis, Ulcerative - pathology; Crohn Disease - metabolism; Crohn Disease - pathology; Female; Gastrointestinal Tract - metabolism; Gastrointestinal Tract - pathology; Humans; Male; Mice; NF-E2-Related Factor 2 - metabolism; Nuclear Proteins - metabolism; tau Proteins - metabolism; Tau; Crohn's disease; enteric nervous system; alpha-synuclein; Nrf2

A sizeable body of evidence has recently emerged to suggest that gastrointestinal (GI) inflammation might be involved in the development of Parkinson's disease (PD). There is now strong epidemiological and genetical evidence linking PD to inflammatory bowel diseases and we recently demonstrated...